scholarly journals Fatal Case of Liver and Brain Abscesses Due to Fusobacterium nucleatum

Cureus ◽  
2021 ◽  
Author(s):  
Nadia Toumeh ◽  
Megha Mudireddy ◽  
Bradley Smith ◽  
Dubert M Guerrero
Keyword(s):  
Fatal Case ◽  
Fusobacterium Nucleatum ◽  
Brain Abscesses

scholarly journals 1636 Diverticulitis Complicated by Fusobacterium Nucleatum Brain Abscesses

2019 ◽  
Vol 114 (1) ◽  
pp. S915-S915
Author(s):  
Bashar Sharma ◽  
Mili Shah ◽  
Marsha Antoine ◽  
Enad Dawod ◽  
Divey Manocha
Keyword(s):  
Fusobacterium Nucleatum ◽  
Brain Abscesses

scholarly journals Fonsecaea pugnacius, a Novel Agent of Disseminated Chromoblastomycosis

2015 ◽  
Vol 53 (8) ◽  
pp. 2674-2685 ◽  
Author(s):  
Conceição M. P. S. de Azevedo ◽  
Renata R. Gomes ◽  
Vania A. Vicente ◽  
Daniel W. C. L. Santos ◽  
Sirlei G. Marques ◽  
...  
Keyword(s):  
Internal Transcribed Spacer ◽  
Novel Species ◽  
Large Subunit ◽  
Fatal Case ◽  
Content Type ◽  
History Of ◽  
Brain Abscesses ◽  
The Right ◽  
The Brain ◽  
Novel Agent

We report a fatal case of a chromoblastomycosis-like infection caused by a novel species ofFonsecaeain a 52-year-old immunocompetent Caucasian male from an area of chromoblastomycosis endemicity in Brazil. The patient had a 30-year history of slowly evolving, verrucous lesions on the right upper arm which gradually affected the entire arm, the left hemifacial area, and the nose. Subsequent dissemination to the brain was observed, which led to death of the patient. The internal transcribed spacer (ITS) and partial large subunit (LSU),BT2, andCDC42genes of the isolates recovered from skin and brain were sequenced, confirming the novelty of the species. The species is clinically unique in causing brain abscesses secondary to chromoblastomycosis lesions despite the apparent intact immunity of the patient. Histopathologic appearances were very different, showing muriform cells in skin and hyphae in brain.

scholarly journals Multiple brain abscesses of gynecologic origin caused by Fusobacterium nucleatum

Réanimation ◽  
2014 ◽  
Vol 23 (3) ◽  
pp. 327-328
Author(s):  
K. Rachdi ◽  
V. Legros ◽  
S. Mestrallet ◽  
B. Just ◽  
P. Mateu
Keyword(s):  
Fusobacterium Nucleatum ◽  
Brain Abscesses

scholarly journals Brain Abscess Associated with Polymicrobial Infection after Intraoral Laceration: A Pediatric Case Report

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Fumihiro Ochi ◽  
Hisamichi Tauchi ◽  
Toyohisa Miyata ◽  
Tomozo Moritani ◽  
Toshiyuki Chisaka ◽  
...  
Keyword(s):  
Brain Abscess ◽  
Antimicrobial Therapy ◽  
Fusobacterium Nucleatum ◽  
Brain Parenchyma ◽  
Pediatric Case ◽  
Parvimonas Micra ◽  
Increased Risk ◽  
Brain Abscesses ◽  
Congenital Cyanotic Heart Disease ◽  
The Brain

Brain abscesses, infections within the brain parenchyma, can arise as complications of various conditions including infections, trauma, and surgery. However, brain abscesses due to polymicrobial organisms have rarely been reported in children. We herein report a case of a 9-year-old girl with unresolved congenital cyanotic heart disease (CCHD) presenting with right hemiplegia who was diagnosed with brain abscess caused by Streptococcus intermedius, Parvimonas micra, and Fusobacterium nucleatum after oropharyngeal injury. She was treated with intravenous antimicrobial therapy, drainage under craniotomy, and antiedema therapy with glycerol and goreisan, which led to the improvement of right hemiplegia to baseline; she was discharged following eight weeks of intravenous antimicrobial therapy. The clinical diagnosis of the brain abscess was difficult due to the nonspecific presentation, highlighting the importance of cranial imaging without haste in patients at increased risk for brain abscesses such as those with CCHD, presenting with fever in the absence of localizing symptoms or fever, accompanied with abnormal neurological findings.

An immunocompetent patient with culture-negative multiple brain abscesses caused by Fusobacterium nucleatum

Anaerobe ◽  
2020 ◽  
Vol 65 ◽  
pp. 102261
Author(s):  
Ariel Kenig ◽  
Asa Kessler ◽  
Shaheen Alaa ◽  
Wadia Hazu ◽  
Ayelet Michael-Gaygo ◽  
...  
Keyword(s):  
Fusobacterium Nucleatum ◽  
Immunocompetent Patient ◽  
Brain Abscesses ◽  
Culture Negative

scholarly journals Multiple Brain Abscesses Caused by Fusobacterium nucleatum Treated Conservatively

2003 ◽  
Vol 30 (3) ◽  
pp. 266-268 ◽  
Author(s):  
Josef G. Heckmann ◽  
Christoph J.G. Lang ◽  
Heinz Hartl ◽  
Bernd Tomandl
Keyword(s):  
Cerebrospinal Fluid ◽  
Fusobacterium Nucleatum ◽  
Signs And Symptoms ◽  
Brain Dysfunction ◽  
Neck Stiffness ◽  
Fluid Analysis ◽  
Brain Abscesses ◽  
Brain Ct Scan ◽  
Diffuse Brain

Background:Multiple brain abscesses are serious neurological problems with high mortality and disabling morbidity. The frequency is rising as a result of AIDS and the increasing number of immunocompromised patients.Case study:A 59-year-old woman developed signs and symptoms of diffuse brain dysfunction including fever and neck stiffness. A brain CT scan demonstrated nine contrast-enhancing ring-shaped lesions. Analysis of the cerebrospinal fluid using PCR-technique revealed DNA of Fusobacterium nucleatum. Conservative treatment with antibiotics was successful. The patient recovered with only mild cognitive deficits.Results:The experience of our patient and the review of the literature indicate that multiple brain abscesses due to Fusobacterium nucleatum are rare. The most probable source is oral infection.Conclusion:Multiple brain abscesses may be caused by Fusobacterium nucleatum. Cerebrospinal fluid analysis using PCR technique is helpful with diagnosis. Conservative management can be successful.

Diagnosis and therapy of brain abscesses

1999 ◽  
Vol 56 (11) ◽  
pp. 659-663 ◽  
Author(s):  
Nau ◽  
Behnke-Mursch
Keyword(s):  
Operative Verfahren ◽  
Diagnosis And Therapy ◽  
Brain Abscesses

Die verursachenden Erreger von Hirnabszessen variieren in Abhängigkeit von der Grunderkrankung. Typisch sind Mischinfektionen aus Aerobiern und Anaerobiern. Hirnabszesse entwickeln sich meist subakut. Sensibelster Entzündungsparameter im Blut ist das C-reaktive Protein (bei 80–90% der Patien-ten erhöht). Die entscheidende diagnostische Maßnahme ist das kraniale CT ohne und mit Kontrastmittel (KM). Die rasche Kultur von Abszeßinhalt durch Punktion, Drainage oder Abszeßexzision ist entscheidend für die Erregeridentifikation. Eine alleinige Chemotherapie zur Abszeßbehandlung wird nur angewandt, wenn 1. multiple, tief gelegene und/oder sehr kleine Abszesse vorliegen oder 2. sich der Patient in einem so schlechten Allgemeinzustand befindet, daß ihm ein invasiver Eingriff nicht zugemutet werden kann oder 3. eine Hirnphlegmone und kein abgekapselter Abszeß vorliegt. Gebräuchliche operative Verfahren sind die Abszeßaspiration (meist nach stereotaktischer Abszeßpunktion), die offene Kraniotomie mit Abszeßexzision und die offene Abszeßevakuation ohne Kapselentfernung. Für die ungezielte Chemotherapie vor Erregernachweis bevorzugen wir die Kombination von Cefotaxim (3×2–4 g/d i.v.) mit Metronidazol (3–4×0,5 g/d i.v.). Kortikosteroide sind indiziert, wenn der Prozeß raumfordernd ist und eine Herniation droht oder multiple Abszesse vorliegen, die nur teilweise operativ angehbar sind, oder Hirnregionen mit besonderer Ödemneigung betroffen sind.

CME-Antworten: «Fusobacterium nucleatum/naviforme – eine seltene, aber nicht zu unterschätzende Ursache für pyogene Leberabszesse» aus Praxis Nr. 19

Praxis ◽  
2018 ◽  
Vol 107 (20) ◽  
pp. 1109-1109
Author(s):  
Mario Rifaat ◽  
Carsten Depmeier ◽  
Victor Jeger ◽  
Markus Schneemann ◽  
Alexia Anagnostopoulos
Keyword(s):  
Fusobacterium Nucleatum
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