scholarly journals Correlation of 25-Hydroxyvitamin D and Serum Lipid Levels Among Patients With Type 2 Diabetes

Cureus ◽  
2021 ◽  
Author(s):  
Ahmed Elshebiny ◽  
Mohmmed A AlHewishel ◽  
Hussain A Al Ghadeer ◽  
Noor Alosaif ◽  
Bashayer F Al Furaikh ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Hydroxyvitamin D ◽  
Serum Lipid Levels ◽  
25 Hydroxyvitamin D

Effects of sitagliptin on serum lipid levels in patients with type 2 diabetes

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Li-Da Wu ◽  
Nan Zhou ◽  
Jin-yu Sun ◽  
Hao Yu ◽  
Ru-Xing Wang
Keyword(s):  
Type 2 Diabetes ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels

Association between DPP4 gene polymorphism and serum lipid levels in Chinese type 2 diabetes individuals

Neuropeptides ◽  
2016 ◽  
Vol 60 ◽  
pp. 1-6 ◽  
Author(s):  
Xiaomin Xing ◽  
Yi Han ◽  
Xiaojun Zhou ◽  
Bo Zhang ◽  
Yan Li ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gene Polymorphism ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels

scholarly journals Effect of Temocapril Hydrochloride on Serum Lipid Levels in Patients with Hypertensive Type 2 Diabetes Mellitus

2001 ◽  
Vol 8 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Yoh Miyashita ◽  
Yoshiaki Ito ◽  
Shoichiro Hasiguchi ◽  
Mitsuya Totsuka ◽  
Akiko Aoki ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels

Association of serum lipid levels with retinal hard exudate area in African Americans with type 2 diabetes

2016 ◽  
Vol 255 (3) ◽  
pp. 509-517 ◽  
Author(s):  
Evangelia Papavasileiou ◽  
Samaneh Davoudi ◽  
Ramak Roohipoor ◽  
Heeyoon Cho ◽  
Shreyas Kudrimoti ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
African Americans ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Hard Exudate ◽  
Serum Lipid Levels

Association of APOA5 −1131T>C Polymorphism and Serum Lipid Levels in Patients with Type 2 Diabetes

2013 ◽  
Vol 32 (10) ◽  
pp. 589-593 ◽  
Author(s):  
Ivana Celap ◽  
Ana-Maria Simundic ◽  
Nora Nikolac ◽  
Sanja Kackov ◽  
Darko Katalinic
Keyword(s):  
Type 2 Diabetes ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels

scholarly journals Association of serum 25-hydroxyvitamin D with metabolic syndrome and type 2 diabetes: a one sample Mendelian randomization study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jing Xiao ◽  
Jingyi Lv ◽  
Shiyu Wang ◽  
Yang Zhou ◽  
Lunwen Chen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Mendelian Randomization ◽  
Middle Aged ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Randomization Analysis

Abstract Background Vitamin D deficiency has been associated with type 2 diabetes (T2D) and metabolic syndrome (MS) and its components. However, it is unclear whether a low concentration of vitamin D is the cause or consequence of these health conditions. Thus, this study aimed to evaluate the association of vitamin D concentrations and its genetic risk scores (GRSs) with MS and its component diseases, such as T2D, in middle-aged and elderly participants from rural eastern China. Methods A subset of 2393 middle-aged and elderly individuals were selected from 70,458 participants of the Nantong Chronic Diseases Study of 2017–2018 in China. We used two 25-hydroxyvitamin D (25[OH]D) synthesis single-nucleotide polymorphisms (SNPs) (DHCR7-rs12785878 and CYP2R1-rs10741657) and two 25(OH) D metabolism SNPs (GC-rs2282679 and CYP24A1-rs6013897) for creating GRSs, which were used as instrumental variables to assess the effect of genetically lowered 25(OH) D concentrations on MS and T2D based on the Wald ratio. F statistics were used to validate that the four SNPs genetically determined 25(OH) D concentrations. Results Compared to vitamin D sufficient individuals, individuals with vitamin D insufficiency had an odds ratio (OR [95% confidence interval {CI}]) of MS of 1.30 (1.06–1.61) and of T2D of 1.32 (1.08–1.64), individuals with vitamin D deficiency had an ORs (95% CI) of MS of 1.50 (1.24–1.79) and of T2D of 1.47 (1.12–1.80), and those with vitamin D severe deficiency had an ORs (95% CI) of MS of 1.52 (1.29–1.85) and of T2D of 1.54 (1.27–1.85). Mendelian randomization analysis showed a 25-nmol/L decrease in genetically instrumented serum 25(OH) D concentrations using the two synthesis SNPs (DHCR7 and CYP2R1 genes) associated with the risk of T2D and abnormal diastolic blood pressure (DBP) with ORs of 1.10 (95%CI: 1.02–1.45) for T2D and 1.14 (95%CI: 1.03–1.43) for DBP. Conclusions This one sample Mendelian randomization analysis shows genetic evidence for a causal role of lower 25(OH) D concentrations in promoting of T2D and abnormal DBP in middle-aged and elderly participants from rural China.

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