scholarly journals An Atypical Pleomorphic Lipomatous Tumor Presenting As Groin Mass

Cureus ◽  
2021 ◽  
Author(s):  
Egon Rodrigues ◽  
Florinda Cardoso ◽  
Horácio Scigliano ◽  
Mário Nora
Keyword(s):  
Lipomatous Tumor

A Case of Atypical Lipomatous Tumor of the Lower Leg

2016 ◽  
Vol 78 (4) ◽  
pp. 379-381 ◽  
Author(s):  
Tatsuya OGAWA ◽  
Shijima TAGUCHI ◽  
Yoshio NAKAYAMA
Keyword(s):  
Lower Leg ◽  
Atypical Lipomatous Tumor ◽  
Lipomatous Tumor

scholarly journals MDM2 Amplified Sarcomas: A Literature Review

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 496
Author(s):  
Raf Sciot
Keyword(s):  
Suppressor Gene ◽  
Negative Regulator ◽  
Low Grade ◽  
P53 Mutations ◽  
Lipomatous Tumor ◽  
Double Minute ◽  
Genetic Features ◽  
Murine Double Minute ◽  
Well Differentiated ◽  
Mdm2 Amplification

Murine Double Minute Clone 2, located at 12q15, is an oncogene that codes for an oncoprotein of which the association with p53 was discovered 30 years ago. The most important function of MDM2 is to control p53 activity; it is in fact the best documented negative regulator of p53. Mutations of the tumor suppressor gene p53 represent the most frequent genetic change in human cancers. By overexpressing MDM2, cancer cells have another means to block p53. The sarcomas in which MDM2 amplification is a hallmark are well-differentiated liposarcoma/atypical lipomatous tumor, dedifferentiated liposarcoma, intimal sarcoma, and low-grade osteosarcoma. The purpose of this review is to summarize the typical clinical, histopathological, immunohistochemical, and genetic features of these tumors.

Pleomorphic fibroma and dermal atypical lipomatous tumor: are they related?

2013 ◽  
Vol 40 (4) ◽  
pp. 379-384 ◽  
Author(s):  
Tariq Al-Zaid ◽  
Wei-Lien Wang ◽  
Dolores Lopez-Terrada ◽  
Dina Lev ◽  
Jason L. Hornick ◽  
...  
Keyword(s):  
Atypical Lipomatous Tumor ◽  
Lipomatous Tumor

scholarly journals Duplication of chromosome segment 12q13-15 in a lipomatous tumor with minimal nuclear atypia: A case report

2016 ◽  
Vol 11 (4) ◽  
pp. 2875-2878
Author(s):  
JUN NISHIO ◽  
HIROSHI IWASAKI ◽  
TERUFUMI SHIBATA ◽  
KAZUKI NABESHIMA ◽  
MASATOSHI NAITO
Keyword(s):  
Case Report ◽  
Chromosome Segment ◽  
Nuclear Atypia ◽  
Lipomatous Tumor

A Well-Differentiated Liposarcoma in the Digit: A Case Report of the 5-Year Post-Surgical Follow-Up

2018 ◽  
Vol 23 (03) ◽  
pp. 415-418
Author(s):  
Sakiko Mizuno ◽  
Kensuke Ochi ◽  
Jun Miyauchi ◽  
Itsuo Watanabe ◽  
Hiraku Hotta ◽  
...  
Keyword(s):  
Case Report ◽  
Local Recurrence ◽  
Hand Function ◽  
Middle Finger ◽  
Imaging Findings ◽  
Lipomatous Tumor ◽  
Imaging Examination ◽  
Well Differentiated

A liposarcoma is extremely rare in the digits. A 73-year-old woman was diagnosed with a lipoma in her middle finger 10 years ago. As this tumor increased in size and presented with imaging findings that were atypical of lipomas, careful marginal resection biopsy outside the pseudo-capsule was performed, and the tumor was diagnosed as a well-differentiated liposarcoma. At the 5-year follow-up, the patient showed no evidence of local recurrence or metastasis, with no loss of hand function. The findings from this case suggest that even for a lipomatous tumor in the digits, further imaging examination and resection biopsy should be considered if the tumor presents with features that are atypical of lipomas.

scholarly journals Spindle Cell Lipoma of the Parapharyngeal Space: First Report of a Case

2001 ◽  
Vol 80 (4) ◽  
pp. 244-250 ◽  
Author(s):  
Ingo Baumann ◽  
Florian Dammann ◽  
Hans Peter Horny ◽  
Peter Karl Plinkert
Keyword(s):  
Spindle Cell ◽  
Parapharyngeal Space ◽  
Subcutaneous Tissue ◽  
Resonance Imaging ◽  
Spindle Cell Lipoma ◽  
Lipomatous Tumor ◽  
Pharyngeal Muscles ◽  
Parapharyngeal Tumor ◽  
The Right ◽  
Total Parotidectomy

Spindle cell lipomas are usually located in the subcutaneous tissue of the back, shoulders, and neck. To our knowledge, the presence of such a tumor in the parapharyngeal space has not yet been described. We evaluated a 45-year-old man with a tender swelling of the right parotid area that had reached the submandibular area. Clinical examination and magnetic resonance imaging revealed the presence of a tumor that coated the parotid area laterally and extended into the center of the parapharyngeal space, thus causing a dislocation of the pharyngeal muscles and mucosa. We performed a total parotidectomy and submandibulectomy on the right side and extirpated the parapharyngeal tumor. We were able to spare the facial nerve, and no facial paralysis occurred. Histologic examination revealed an atypical lipomatous tumor with a remarkably large portion of spindles.

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