scholarly journals Endoscopic Spinal Decompression: A Retrospective Review of Pain Outcomes at an Academic Medical Center

Cureus ◽  
2021 ◽  
Author(s):  
Geoffrey D Panjeton ◽  
Holden L Brown ◽  
Sam Searcy ◽  
Matthew Meroney ◽  
Sanjeev Kumar
Keyword(s):  
Retrospective Review ◽  
Medical Center ◽  
Academic Medical Center ◽  
Spinal Decompression ◽  
Academic Medical ◽  
Pain Outcomes

scholarly journals 154. Antibiotic Use During Three Separate Waves of the COVID-19 Pandemic at a Large Academic Medical Center in Detroit, MI

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S188-S189
Author(s):  
Deepika Sivakumar ◽  
Shelbye R Herbin ◽  
Raymond Yost ◽  
Marco R Scipione
Keyword(s):  
Retrospective Review ◽  
Bacterial Pneumonia ◽  
Medical Center ◽  
Academic Medical Center ◽  
Antibiotic Use ◽  
Percent Change ◽  
Academic Medical ◽  
Days Of Therapy ◽  
Time Periods ◽  
The Impact

Abstract Background Inpatient antibiotic use early on in the COVID-19 pandemic may have increased due to the inability to distinguish between bacterial and COVID-19 pneumonia. The purpose of this study was to determine the impact of COVID-19 on antimicrobial usage during three separate waves of the COVID-19 pandemic. Methods We conducted a retrospective review of patients admitted to Detroit Medical Center between 3/10/19 to 4/24/21. Median days of therapy per 1000 adjusted patient days (DOT/1000 pt days) was evaluated for all administered antibiotics included in our pneumonia guidelines during 4 separate time periods: pre-COVID (3/3/19-4/27/19); 1st wave (3/8/20-5/2/20); 2nd wave (12/6/21-1/30/21); and 3rd wave (3/7/21-4/24/21). Antibiotics included in our pneumonia guidelines include: amoxicillin, azithromycin, aztreonam, ceftriaxone, cefepime, ciprofloxacin, doxycycline, linezolid, meropenem, moxifloxacin, piperacillin-tazobactam, tobramycin, and vancomycin. The percent change in antibiotic use between the separate time periods was also evaluated. Results An increase in antibiotics was seen during the 1st wave compared to the pre-COVID period (2639 [IQR 2339-3439] DOT/1000 pt days vs. 2432 [IQR 2291-2499] DOT/1000 pt days, p=0.08). This corresponded to an increase of 8.5% during the 1st wave. This increase did not persist during the 2nd and 3rd waves of the pandemic, and the use decreased by 8% and 16%, respectively, compared to the pre-COVID period. There was an increased use of ceftriaxone (+6.5%, p=0.23), doxycycline (+46%, p=0.13), linezolid (+61%, p=0.014), cefepime (+50%, p=0.001), and meropenem (+29%, p=0.25) during the 1st wave compared to the pre-COVID period. Linezolid (+39%, p=0.013), cefepime (+47%, p=0.08) and tobramycin (+47%, p=0.05) use remained high during the 3rd wave compared to the pre-COVID period, but the use was lower when compared to the 1st and 2nd waves. Figure 1. Antibiotic Use 01/2019 to 04/2019 Conclusion Antibiotics used to treat bacterial pneumonia during the 1st wave of the pandemic increased and there was a shift to broader spectrum agents during that period. The increased use was not sustained during the 2nd and 3rd waves of the pandemic, possibly due to the increased awareness of the differences between patients who present with COVID-19 pneumonia and bacterial pneumonia. Disclosures All Authors: No reported disclosures

Comparison of two different intravenous serotonin antagonists used for chemotherapy-induced nausea and vomiting prophylaxis in patients treated with moderately emetogenic risk regimens: A retrospective analysis from a large academic medical center

2020 ◽  
Vol 26 (8) ◽  
pp. 1964-1969
Author(s):  
Melissa Gamble ◽  
Elisabeth Carroll ◽  
Garth C Wright ◽  
Ashley E Glode
Keyword(s):  
Retrospective Review ◽  
Medical Center ◽  
Academic Medical Center ◽  
Emetogenic Chemotherapy ◽  
Nausea And Vomiting ◽  
Moderately Emetogenic Chemotherapy ◽  
Prophylactic Regimen ◽  
Nccn Guidelines ◽  
Institutional Review ◽  
Academic Medical

Introduction Chemotherapy-induced nausea and vomiting (CINV) can be a serious and debilitating adverse effect that is highly feared by cancer patients. For patients receiving moderately emetogenic chemotherapy regimens at our institution in the ambulatory infusion center, palonosetron was selected as the preferred serotonin (5-HT3) antagonist for CINV prophylaxis per the 2016 NCCN Guidelines, when a neurokinin1 antagonist was not included in the prophylactic regimen. The purpose of this study was to evaluate the efficacy of dexamethasone and palonosetron versus granisetron for the prevention of CINV in patients receiving moderately emetogenic chemotherapy regimens. Methods This study is an Institutional Review Board-approved, single-center retrospective review of electronic health records including patients who received moderately emetogenic chemotherapy regimens with CINV prophylaxis with dexamethasone and either palonosetron or granisetron. Results A total of 268 eligible patients were included in the study. Eighty-eight patients received palonosetron and 180 patients received granisetron as their 5-HT3 receptor antagonist between October 31, 2014 and October 31, 2016. There were no statistically significant differences between the two antiemetic groups for the primary outcome of presence of any change in day 1 intravenous prophylactic antiemetics. Nine (10.23%) palonosetron patients and 15 (8.33%) granisetron patients required a change in their day 1 intravenous prophylactic antiemetics ( P = 0.610). Conclusions Despite palonosetron’s better efficacy, longer half-life, and higher binding affinity, the results of this retrospective review demonstrates that the choice of serotonin antagonist, palonosetron or granisetron, did not result in a change in day 1 intravenous prophylactic antiemetics or antiemetic outpatient medications for patients undergoing moderately emetogenic chemotherapy regimens.

scholarly journals Evaluation of a hybrid antimicrobial restriction process at a large academic medical center

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Jesse D. Smith ◽  
Linh H. Nguyen ◽  
Tamara Krekel ◽  
Jerrica Waggoner ◽  
David J. Ritchie ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Medical Center ◽  
Academic Medical Center ◽  
Appropriate Use Criteria ◽  
Appropriate Use ◽  
Academic Medical

Abstract We conducted a retrospective review of a hybrid antimicrobial restriction process demonstrating adherence to appropriate use criteria in 72% of provisional-only orders, in 100% of provisional orders followed by ID orders, and in 97% of ID-initiated orders. Therapy interruptions occurred in 24% of provisional orders followed by ID orders.

scholarly journals Transmission risk of SARS-CoV-2 to healthcare personnel following unanticipated exposure to aerosol generating procedures: Experience from epidemiologic investigations at an academic medical center

2021 ◽  
pp. 1-10
Author(s):  
Sharon Fawcett ◽  
Meghan Madhusudhan ◽  
Emily Gaddam ◽  
Matthew Almario ◽  
Shawna Misah ◽  
...  
Keyword(s):  
At Risk ◽  
Infection Rate ◽  
Retrospective Review ◽  
Medical Center ◽  
Academic Medical Center ◽  
Transmission Risk ◽  
Healthcare Personnel ◽  
Risk Of Infection ◽  
Eye Protection ◽  
Academic Medical

Abstract Healthcare personnel (HCP) with unprotected exposures to aerosol generating procedures (AGP) on patients with COVID-19 are at risk of infection with SARS-CoV-2. A retrospective review at an academic medical center demonstrated a less than 1% infection rate among HCP involved in AGP without a respirator and/or eye protection.

Gender differences in career progress and satisfaction in an academic medical center

2002 ◽  
Vol 2 (3) ◽  
pp. 95-104 ◽  
Author(s):  
JoAnn Manson ◽  
Beverly Rockhill ◽  
Margery Resnick ◽  
Eleanor Shore ◽  
Carol Nadelson ◽  
...  
Keyword(s):  
Gender Differences ◽  
Medical Center ◽  
Academic Medical Center ◽  
Academic Medical ◽  
Career Progress
Sign in / Sign up

Export Citation Format

Share Document