scholarly journals The Significance of Topoisomerase II Alpha in Invasive Breast Carcinoma

Cureus ◽  
2021 ◽  
Author(s):  
M Arthi ◽  
K Arun Kumar ◽  
Lawrence D'Cruze ◽  
Rajendiran S ◽  
Leena D Joseph ◽  
...  
2010 ◽  
Vol 2010 ◽  
pp. 1-14 ◽  
Author(s):  
Ettie Piura ◽  
Benjamin Piura

Autoantibodies (AAbs) to tumor-associated antigens (TAAs) have been identified in the circulation of patients with cancer. This paper will focus on recent knowledge related to circulating AAbs to TAAs in breast carcinoma. So far, the following TAAs have been identified to elicit circulating AAbs in breast carcinoma: p53, MUC-1, heat shock proteins (HSP-27, HSP-60, and HSP-90), HER2/neu/c-erb B2, GIPC-1, c-myc, c-myb, cancer-testis antigens (NY-ESO-1), BRCA1, BRCA2, endostatin, lipophilin B, cyclin B1, cyclin D1, fibulin, insulin-like growth factor binding protein 2 (IGFBP-2), topoisomerase II alpha (TOPO2α), and cathepsin D. Measurement of serum AAbs to one specific TAA only is of little value for screening and early diagnosis of breast carcinoma; however, assessment of AAbs to a panel of TAAs may have promising diagnostic potential.


2006 ◽  
Vol 128 (05) ◽  
Author(s):  
S Albrich ◽  
E Bremer ◽  
M Schmidt ◽  
A Victor ◽  
S Gebhard ◽  
...  

2018 ◽  
Author(s):  
Emna Elfaleh ◽  
Ibtissem Oueslati ◽  
Melika Chihaoui ◽  
Meriem Yazidi ◽  
Fatma Chaker ◽  
...  

2019 ◽  
Author(s):  
Giovanni Corso ◽  
Patrick Maisonneuve ◽  
Giulia Massari ◽  
Alessandra Invento ◽  
Gabriella Pravettoni ◽  
...  

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