scholarly journals Metformin-Induced Hemolysis in a Patient With Glucose-6-Phosphate Dehydrogenase Deficiency Presenting With Concurrent Idiopathic Steven-Johnson Syndrome/Toxic Epidermal Necrolysis

Cureus ◽  
2021 ◽  
Author(s):  
Avijoy Roy Choudhury ◽  
Cecilia Gadaga ◽  
Layuren Moodley ◽  
Aru Moodley
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Dehydrogenase Deficiency ◽  
Johnson Syndrome ◽  
Steven Johnson Syndrome ◽  
Glucose 6 Phosphate Dehydrogenase

scholarly journals Toxic Epidermal Necrolysis and Steven–Johnson Syndrome: A Comprehensive Review

2020 ◽  
Vol 9 (7) ◽  
pp. 426-439 ◽  
Author(s):  
Olivia A. Charlton ◽  
Victoria Harris ◽  
Kevin Phan ◽  
Erin Mewton ◽  
Chris Jackson ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Comprehensive Review ◽  
Johnson Syndrome ◽  
Steven Johnson Syndrome

scholarly journals DRUG-INDUCED STEVENS-JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS

2016 ◽  
Vol 65 (4) ◽  
pp. 377-381
Author(s):  
Dalia Dop ◽  
◽  
Desdemona Stepan ◽  
Cristian Gheonea ◽  
Elena Carmen Niculescu ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Rare Diseases ◽  
Intravenous Immunoglobulins ◽  
Stevens Johnson Syndrome ◽  
Drug Induced ◽  
Johnson Syndrome ◽  
Medical Emergencies ◽  
Steven Johnson Syndrome ◽  
Restitutio Ad Integrum

Steven-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare diseases that appear following the administration of risk drugs. Both are severity grades of the same condition and are considered medical emergencies, because they are potentially lethal. They are characterized by mucocutaneous tenderness, erythema, necrosis and bullous detachment similar to extended burns. We report 3 cases of SJS/TEN in which the etiology was probably drug-related (Paracetamol, Atomoxetinum, Sulfamethoxazolum + trimethoprinum), with restitutio ad integrum following the administration of intravenous immunoglobulins.

scholarly journals Steven-Johnson Syndrome in Child

2019 ◽  
Vol 70 (9) ◽  
pp. 3213-3215
Author(s):  
Ramona Mihaela Nedelcuta ◽  
Vlad Dumitru Baleanu ◽  
Dragos Virgil Davitoiu ◽  
Tiberiu Stefanita Tenea Cojan ◽  
Cosmin Alexandru Ciora ◽  
...  
Keyword(s):  
Drug Abuse ◽  
Toxic Epidermal Necrolysis ◽  
Rare Diseases ◽  
Early Investigation ◽  
Direct Relation ◽  
Skin Damage ◽  
Effective Prevention ◽  
Johnson Syndrome ◽  
Skin Integrity ◽  
Steven Johnson Syndrome

Steven-Johnson Syndrome and NET (toxic epidermal necrolysis), different expressions of the same condition were named according to the percentage of affected skin: [10% in Steven-Johnson Syndrome and]30% in NET. Small ages may be a target for these rare diseases, in direct relation to drug abuse (antibiotics, NSAIDs, antiepileptics, etc.). Survival depends on the rapid response of the causative agent, the early investigation of the therapy to block Fas-FasL interaction and to reestablish skin integrity (Fas-receptor on the surface of cells involved in apoptosis). Massive skin damage is associated with a severe prognosis, as is the age of the baby.It is necessary to use wise the medication or automedication for a complete and effective prevention of Steven-Johnson Syndrome.

scholarly journals A Case Study of Stevens–Johnson Syndrome-Toxic Epidermal Necrolysis (SJS-TEN) Overlap in Mycoplasma pneumoniae-Associated Tracheobronchitis

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Ranjit Sah ◽  
Samikshya Neupane ◽  
Shusila Khadka ◽  
Sagar Poudyal ◽  
Hem Raj Paneru ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Mycoplasma Pneumoniae ◽  
Respiratory Tract Infections ◽  
Medical Emergency ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome ◽  
Steven Johnson Syndrome ◽  
Tract Infections ◽  
Simple Bedside

Stevens–Johnson syndrome is a medical emergency which is characterized by skin and mucosal reaction to the use of certain drugs. Atypical Steven–Johnson syndrome can occur due to various microorganisms and Mycoplasma pneumoniae being one of them. We present a clinical course, diagnosis, and successful management of Steven–Johnson syndrome-toxic epidermal necrolysis (SJS-TEN) overlap due to Mycoplasma pneumoniae in a 17-year-old Nepalese female. In the resource-limiting country and hospitals where serology and PCR for M. pneumoniae is not easily accessible, a simple bedside cold agglutination test can be done to increase the suspicion of infectious cause (most common M. pneumoniae ) of SJS-TEN overlap. M. pneumoniae infection should be considered in all cases of mucositis, especially in patients having preceding respiratory tract infections (tracheobronchitis).

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