scholarly journals Chemodenervation for Oromandibular Dystonia Utilizing Botulinum Toxins

Cureus ◽  
2021 ◽  
Author(s):  
Muhammad Atif Ameer ◽  
Danish Bhatti
Keyword(s):  
Oromandibular Dystonia ◽  
Botulinum Toxins

scholarly journals Treatment of Blepharospasm and Oromandibular Dystonia with Botulinum Toxins

Toxins ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 269 ◽  
Author(s):  
Travis J.W. Hassell ◽  
David Charles
Keyword(s):  
Site Selection ◽  
Botulinum Neurotoxin ◽  
Clinical Evidence ◽  
Standard Of Care ◽  
Oromandibular Dystonia ◽  
Botulinum Toxins ◽  
First Line ◽  
First Line Therapy ◽  
Line Therapy ◽  
History Of

Blepharospasm and oromandibular dystonia are focal dystonias characterized by involuntary and often patterned, repetitive muscle contractions. There is a long history of medical and surgical therapies, with the current first-line therapy, botulinum neurotoxin (BoNT), becoming standard of care in 1989. This comprehensive review utilized MEDLINE and PubMed and provides an overview of the history of these focal dystonias, BoNT, and the use of toxin to treat them. We present the levels of clinical evidence for each toxin for both, focal dystonias and offer guidance for muscle and site selection as well as dosing.

Chemodenervation of oromandibular dystonia with botulinum toxins: Five-year experience

Toxicon ◽  
2021 ◽  
Vol 190 ◽  
pp. S5
Author(s):  
Muhammad Atif Ameer ◽  
Nabeel Syed ◽  
John Bertoni ◽  
Amy Hellman ◽  
Diego Torres-Russotto ◽  
...  
Keyword(s):  
Oromandibular Dystonia ◽  
Botulinum Toxins

Botulinum Toxins Get New Generic Names

2009 ◽  
Vol 40 (9) ◽  
pp. 4
Author(s):  
ALICIA AULT
Keyword(s):  
Botulinum Toxins

Using Botulinum Toxins Cosmetically

2003 ◽  
Author(s):  
Jean Carruthrs ◽  
Alastair Carruthrs
Keyword(s):  
Botulinum Toxins

Cefixime-induced Oromandibular Dystonia in an Adult: A Case Report

2017 ◽  
Vol 12 (2) ◽  
Author(s):  
Lisa Mondet ◽  
Fanny Radoube ◽  
Valerie Gras ◽  
Kamel Masmoudi
Keyword(s):  
Case Report ◽  
Oromandibular Dystonia

scholarly journals FDA Approvals and Consensus Guidelines for Botulinum Toxins in the Treatment of Dystonia

Toxins ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 332 ◽  
Author(s):  
Lauren L. Spiegel ◽  
Jill L. Ostrem ◽  
Ian O. Bledsoe
Keyword(s):  
Botulinum Toxin ◽  
Literature Review ◽  
American Academy ◽  
Practice Guidelines ◽  
European Federation ◽  
Botulinum Toxins ◽  
Consensus Guidelines ◽  
Off Label ◽  
Fda Approval ◽  
American Academy Of Neurology

In 2016, the American Academy of Neurology (AAN) published practice guidelines for botulinum toxin (BoNT) in the treatment of blepharospasm, cervical dystonia, adult spasticity, and headache. This article, focusing on dystonia, provides context for these guidelines through literature review. Studies that led to Food and Drug Administration (FDA) approval of each toxin for dystonia indications are reviewed, in addition to several studies highlighted by the AAN guidelines. The AAN guidelines for the use of BoNT in dystonia are compared with those of the European Federation of the Neurological Societies (EFNS), and common off-label uses for BoNT in dystonia are discussed. Toxins not currently FDA-approved for the treatment of dystonia are additionally reviewed. In the future, additional toxins may become FDA-approved for the treatment of dystonia given expanding research in this area.

scholarly journals Electrical Stimulation of Injected Muscles to Boost Botulinum Toxin Effect on Spasticity: Rationale, Systematic Review and State of the Art

Toxins ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 303
Author(s):  
Alessandro Picelli ◽  
Mirko Filippetti ◽  
Giorgio Sandrini ◽  
Cristina Tassorelli ◽  
Roberto De Icco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Electrical Stimulation ◽  
Botulinum Toxin ◽  
Current Literature ◽  
Electric Stimulation ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Botulinum Toxins ◽  
Stimulation Of

Botulinum toxin type A (BoNT-A) represents a first-line treatment for spasticity, a common disabling consequence of many neurological diseases. Electrical stimulation of motor nerve endings has been reported to boost the effect of BoNT-A. To date, a wide range of stimulation protocols has been proposed in the literature. We conducted a systematic review of current literature on the protocols of electrical stimulation to boost the effect of BoNT-A injection in patients with spasticity. A systematic search using the MeSH terms “electric stimulation”, “muscle spasticity” and “botulinum toxins” and strings “electric stimulation [mh] OR electrical stimulation AND muscle spasticity [mh] OR spasticity AND botulinum toxins [mh] OR botulinum toxin type A” was conducted on PubMed, Scopus, PEDro and Cochrane library electronic databases. Full-text articles written in English and published from database inception to March 2021 were included. Data on patient characteristics, electrical stimulation protocols and outcome measures were collected. This systematic review provides a complete overview of current literature on the role of electrical stimulation to boost the effect of BoNT-A injection for spasticity, together with a critical discussion on its rationale based on the neurobiology of BoNT-A uptake.

Sign in / Sign up

Export Citation Format

Share Document