scholarly journals Advanced Age and Multiple Comorbidities as Important Factors in Predicting Poor Prognosis in Herpes Zoster Ophthalmicus

Cureus ◽  
2021 ◽  
Author(s):  
Asuman Orhan Varoğlu ◽  
Aysenur Avarisli
Keyword(s):  
Herpes Zoster ◽  
Poor Prognosis ◽  
Advanced Age ◽  
Herpes Zoster Ophthalmicus

scholarly journals Ocular manifestation and visual outcomes in herpes zoster ophthalmicus: a prospective study from a tertiary hospital of Eastern India

2021 ◽  
Vol 14 (12) ◽  
pp. 1950-1956
Author(s):  
Mayukh Goswami ◽  
◽  
Manas Bandyopadhyay ◽  
Keyword(s):  
Herpes Zoster ◽  
Optic Neuritis ◽  
Prospective Study ◽  
Anterior Uveitis ◽  
Visual Outcome ◽  
Advanced Age ◽  
Ocular Manifestation ◽  
Herpes Zoster Ophthalmicus ◽  
Visual Outcomes

AIM: To estimate the magnitude of different ocular manifestation in clinically established herpes zoster ophthalmicus (HZO) patients and assessment of the visual outcome after two months of initial examination. METHODS: An observational prospective study was conducted on 42 clinically diagnosed Tzanck smear positive cases HZO to observe the occurrence and frequency of different ocular manifestation and their visual outcome in 10-month period with 2mo follow up. Full ophthalmological examination using slit lamp, non-contact tonometry, applanation tonometry, direct and indirect ophthalmoscope were performed. RESULTS: Out of 42 patients of HZO, 33 had one or more type of ocular manifestation staring from lid skin involvement to conjunctivitis, keratitis, uveitis, increased intraocular pressure (IOP) and optic neuritis but no retinal manifestation. More number of HZO cases and ocular manifestation were found with advancement of ages. Young HZO patients were more associated with human immunodeficiency virus (HIV) infection and HIV infected people with HZO infection had more ocular manifestation. Male to female ratio was 2:1 among HZO cases but ocular manifestation occurred more among males. Female with advanced age were involved more. Lid involvement (73.81%), conjunctivitis (69.05%), and keratitis (59.52%) were most common ocular manifestation followed by anterior uveitis (30.95%) and episcleritis (11.90%). Ocular hypertension (42.86%) was associated with almost every ocular manifestation. Among the cases of more than 45 years of age, 9.52% patients acquired 6/6 vision compared to 7.14% patients at and below 45 years of age after 8wk of follow up. CONCLUSION: The visual outcomes are poor in HZO with advanced age group. Visual outcome of the affected eyes is poor than unaffected eyes. The loss of vision is mainly due to keratitis, anterior uveitis, posterior uveitis, and optic neuritis.

Study of clinical features and management of herpes zoster ophthalmicus

2019 ◽  
Vol 11 (2) ◽  
pp. 62-66
Author(s):  
Prachee Nagrale ◽  
◽  
Vijaykumar Kesharaju ◽  
Sahitya Gogineni ◽  
◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Clinical Features ◽  
Herpes Zoster Ophthalmicus

scholarly journals Corrigendum: The Effects of 830 nm Light-Emitting Diode Therapy on Acute Herpes Zoster Ophthalmicus: A Pilot Study

2013 ◽  
Vol 25 (3) ◽  
pp. 400
Author(s):  
Kui Young Park ◽  
Tae Young Han ◽  
In Su Kim ◽  
In Kwon Yeo ◽  
Beom Joon Kim ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Pilot Study ◽  
Light Emitting Diode ◽  
Herpes Zoster Ophthalmicus ◽  
Light Emitting ◽  
Acute Herpes Zoster

scholarly journals Risk factors of poor prognosis and impairment of activities of daily living in patients with hemorrhagic gastroduodenal ulcers

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Junya Arai ◽  
Jun Kato ◽  
Nobuo Toda ◽  
Ken Kurokawa ◽  
Chikako Shibata ◽  
...  
Keyword(s):  
Risk Factors ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Poor Prognosis ◽  
Significant Risk ◽  
Care Facility ◽  
Significant Risk Factor ◽  
Advanced Age ◽  
Gastroduodenal Ulcers ◽  
Poor Outcomes

Abstract Background Impairment of activities of daily living (ADL) due to hemorrhagic gastroduodenal ulcers (HGU) has rarely been evaluated. We analyzed the risk factors of poor prognosis, including mortality and impairment of ADL, in patients with HGU. Methods In total, 582 patients diagnosed with HGU were retrospectively analyzed. Admission to a care facility or the need for home adaptations during hospitalization were defined as ADL decline. The clinical factors were evaluated: endoscopic features, need for interventional endoscopic procedures, comorbidities, symptoms, and medications. The risk factors of outcomes were examined with multivariate analysis. Results Advanced age (> 75 years) was a significant predictor of poor prognosis, including impairment of ADL. Additional significant risk factors were renal disease (odds ratio [OR] 3.43; 95% confidence interval [CI] 1.44–8.14) for overall mortality, proton pump inhibitor (PPIs) usage prior to hemorrhage (OR 5.80; 95% CI 2.08–16.2), and heart disease (OR 3.05; 95% CI 1.11–8.43) for the impairment of ADL. Analysis of elderly (> 75 years) subjects alone also revealed that use of PPIs prior to hemorrhage was a significant predictor for the impairment of ADL (OR 8.24; 95% CI 2.36–28.7). Conclusion In addition to advanced age, the presence of comorbidities was a risk of poor outcomes in patients with HGU. PPI use prior to hemorrhage was a significant risk factor for the impairment of ADL, both in overall HGU patients and in elderly patients alone. These findings suggest that the current strategy for PPI use needs reconsideration.

scholarly journals Incidence Rate of Herpes Zoster Ophthalmicus

Ophthalmology ◽  
2020 ◽  
Vol 127 (3) ◽  
pp. 324-330 ◽  
Author(s):  
Christina L. Kong ◽  
Ryan R. Thompson ◽  
Travis C. Porco ◽  
Eric Kim ◽  
Nisha R. Acharya
Keyword(s):  
Herpes Zoster ◽  
Incidence Rate ◽  
Herpes Zoster Ophthalmicus
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