scholarly journals Iron Deficiency-Induced Changes in the Hippocampus, Corpus Striatum, and Monoamines Levels That Lead to Anxiety, Depression, Sleep Disorders, and Psychotic Disorders

Cureus ◽  
2021 ◽  
Author(s):  
Hira E Shah ◽  
Nitin Bhawnani ◽  
Aarthi Ethirajulu ◽  
Almothana Alkasabera ◽  
Chike B Onyali ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Sleep Disorders ◽  
Psychotic Disorders ◽  
Corpus Striatum ◽  
Induced Changes ◽  
Anxiety Depression

scholarly journals Psychiatric disorders risk in patients with iron deficiency anemia and association with iron supplementation medications: a nationwide database analysis

2019 ◽  
Author(s):  
Herng-Sheng Lee ◽  
Hsin-Hao Chao ◽  
Wan-Ting Huang ◽  
Solomon Chih-Cheng Chen ◽  
Hsin-Yi Yang
Keyword(s):  
Iron Deficiency ◽  
Sleep Disorders ◽  
Psychiatric Disorders ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
Psychotic Disorders ◽  
Psychiatric Morbidity ◽  
Cox Proportional Hazards ◽  
Deficiency Anemia ◽  
Increased Risk

Abstract Background It has been shown that iron deficiency anemia (IDA) is associated with psychosocial consequences and psychiatric morbidity. However, the association between adults with IDA and psychiatric disorders has not been clarified. The purpose of this study is to investigate the psychiatric disorders morbidity of IDA in comparison with non-IDA group and to examine the risk of psychiatric disorders in IDA patients treated with iron supplementary.Methods All study subjects aged ≥ 20 years with newly diagnosed IDA in the Taiwan National Health Insurance Database during 2000-2012 were enrolled. We matched IDA and non-IDA subjects according to age and gender in a 1:2 ratio. Our primary outcome was diagnosis of psychiatric disorders and the patients were monitored until the end of 2013. The Cox proportional hazards regression model was used to evaluate the risk of psychiatric disorders events to occur in IDA.Results The adjusted hazard ratios (aHR) of psychiatric disorders was 1.49 (95% CI = 1.43 – 1.56) in the IDA group compared with the non-IDA group. Among the different type of psychiatric disorders occurrence, the IDA group was associated with significantly higher incidence and risks of dementia, anxiety disorders, depression, sleep disorders and psychotic disorders (p < 0.05). Furthermore, iron supplementation use to IDA subjects was associated with significantly lower risk of psychiatric disorders compared with IDA patients without iron supplementation.Conclusions Our study indicates that IDA had an increased risk of psychiatric disorders, regardless of other confounders. Moreover, in IDA patients, iron supplementation use could reduce the risk of psychiatric disorders, especially sleep disorders.

scholarly journals Psychiatric disorders risk in patients with iron deficiency anemia and association with iron supplementation medications: a nationwide database analysis

2020 ◽  
Author(s):  
Herng-Sheng Lee ◽  
Hsin-Hao Chao ◽  
Wan-Ting Huang ◽  
Solomon Chih-Cheng Chen ◽  
Hsin-Yi Yang
Keyword(s):  
Iron Deficiency ◽  
Sleep Disorders ◽  
Psychiatric Disorders ◽  
Iron Deficiency Anemia ◽  
Lower Risk ◽  
Iron Supplementation ◽  
Psychotic Disorders ◽  
Psychiatric Morbidity ◽  
Deficiency Anemia ◽  
Increased Risk

Abstract Background: It has been shown that iron deficiency anemia (IDA) is associated with psychosocial consequences and psychiatric morbidity. However, the association between adults with IDA and psychiatric disorders has not been clarified. The purpose of this study was to investigate the psychiatric disorder morbidity of an IDA group in comparison with a non-IDA group and to examine the risk of psychiatric disorders in IDA patients treated with iron supplementation. Methods: All study subjects were 20 years of age or over with newly diagnosed IDA enrolled in the Taiwan National Health Insurance Database from 2000 to 2012. We matched IDA and non-IDA subjects according to age and gender in a 1:2 ratio. Our primary outcome was diagnosis of psychiatric disorders and the patients were monitored until the end of 2013. A multivariate Cox proportional hazards regression model was used to explore the risk of psychiatric disorders in patients with IDA after adjustment for confounders, including demographic characteristics and comorbidities. Results: The adjusted hazard ratios (aHRs) of psychiatric disorders was 1.49 (95% CI = 1.43–1.56) in the IDA group compared with the non-IDA group. Among the different types of psychiatric disorders, the IDA group was associated with significantly higher incidence and risks of dementia, anxiety disorders, depression, sleep disorders, and psychotic disorders ( p < 0.05). Furthermore, iron supplementation in IDA subjects was associated with a significantly lower risk of psychiatric disorders compared to non-iron supplementation in IDA patients. Conclusions: Our study indicates that IDA subjects had an increased risk of psychiatric disorders, regardless of other confounders. In IDA patients, iron supplementation was associated with a decreased risk of psychiatric disorders. Moreover, IDA patients receiving iron supplementation also had a lower risk of sleep disorders.

scholarly journals Association of gastroesophageal reflux disease with anxiety, depression, and sleep disorders

2020 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
S Shanmugapriya ◽  
A Saravanan ◽  
S Shuruthi ◽  
JSuriya Dharsini ◽  
T Saravanan
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Sleep Disorders ◽  
Reflux Disease ◽  
Anxiety Depression

‘Soother of mind’ – meditation in psychiatric disorders: a narrative review

2021 ◽  
pp. 1-7
Author(s):  
Vinod Kumar ◽  
Shree Raksha Bhide ◽  
Rashmi Arasappa ◽  
Shivarama Varambally ◽  
Bangalore N. Gangadhar
Keyword(s):  
Psychiatric Disorders ◽  
Negative Symptoms ◽  
Psychotic Disorders ◽  
Psychotic Symptoms ◽  
Complete Absorption ◽  
Psychiatric Conditions ◽  
Biological Aspects ◽  
The Mind ◽  
Anxiety Depression ◽  
Meditative Practices

SUMMARY Meditation, a component of ashtanga yoga, is an act of inward contemplation in which the mind fluctuates between a state of attention to a stimulus and complete absorption in it. Some forms of meditation have been found to be useful for people with psychiatric conditions such as anxiety, depression and substance use disorder. Evidence for usefulness of meditation for people with psychotic disorders is mixed, with reported improvements in negative symptoms but the emergence/precipitation of psychotic symptoms. This article narrates the benefits of meditation in psychiatric disorders, understanding meditation from the yoga perspective, biological aspects of meditation and practical tips for the practice of meditation. We also explain possible ways of modifying meditative practices to make them safe and useful for the patient population and useful overall as a society-level intervention.

Serum Transferrin Receptor and Transferrin Receptor-Ferritin Index Identify Healthy Subjects With Subclinical Iron Deficits

Blood ◽  
1998 ◽  
Vol 92 (8) ◽  
pp. 2934-2939 ◽  
Author(s):  
Pauli Suominen ◽  
Kari Punnonen ◽  
Allan Rajamäki ◽  
Kerttu Irjala
Keyword(s):  
Iron Deficiency ◽  
Transferrin Receptor ◽  
Iron Supplementation ◽  
Iron Status ◽  
Serum Transferrin ◽  
Serum Transferrin Receptor ◽  
Iron Deficient ◽  
American Society ◽  
Induced Changes ◽  
Apparently Healthy

Despite the established utility of serum transferrin receptor (sTfR), serum ferritin, and the sTfR/log ferritin ratio (TfR-F Index) in the diagnosis of iron deficiency (ID) anemia, the numeric values of these parameters, which are indicative of subclinical ID, remain to be clearly defined. In this study, 65 apparently healthy nonanemic adults (22 men and 43 women) were treated with 3 months of oral iron supplementation to evaluate its effect on parameters reflecting iron status and to determine the prevalence of subclinical iron deficiency in apparently healthy adults. Significant supplementation-induced changes were observed in sTfR, ferritin, and TfR-F Index values in women, whereas in men, none of the studied parameters showed any significant change. Iron-deficient erythropoiesis (IDE) was not observed in men, but was found in 17 women (40%). Although individuals with a compromised iron status may be represented in substantial numbers in conventional reference populations, they can be readily identified using sTfR, ferritin, and TfR-F Index determinations. © 1998 by The American Society of Hematology.

scholarly journals Posttreatment Anxiety, Depression, Sleep Disorders, and Associated Factors in Women Who Survive Breast Cancer

2021 ◽  
Vol 8 (2) ◽  
pp. 147
Author(s):  
Ourania Govina ◽  
Penelope Aggeli ◽  
Georgia Fasoi ◽  
Afroditi Zartaloudi ◽  
Konstantinos Kontzoglou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Sleep Disorders ◽  
Associated Factors ◽  
Anxiety Depression

scholarly journals Iron Deficiency Induced Changes in Iron Reductase Activity in Papaya Roots

2002 ◽  
Vol 127 (2) ◽  
pp. 184-187 ◽  
Author(s):  
Thomas E. Marler ◽  
Ruben dela Cruz ◽  
Andrea L. Blas
Keyword(s):  
Glycine Max ◽  
Iron Deficiency ◽  
Carica Papaya ◽  
Reductase Activity ◽  
Fe Deficiency ◽  
Root Tip ◽  
Root Tips ◽  
Soybean Line ◽  
Induced Changes ◽  
Iron Reductase

Four papaya (Carica papaya L.) cultivars were cultured aeroponically or in perlite to determine the magnitude, timing, and root locality of Fe reductase induced by Fe deficiency. Five soybean [Glycine max (L.) Merrill] lines with a known range of Fe-deficiency chlorosis scores were cultured in perlite for comparison. Speed of inducement of Fe reductase activity was determined in plants cultured without Fe for 0 to 17 days. Location of Fe reductase activity was determined by sectioning roots from the tip to 60 to 70 mm proximal to the root tip from plants cultured without Fe for 16 to 19 days. The Fe reductase system was induced in all papaya cultivars after 7 to 11 days without Fe, and activity increased through 17 days. Iron reductase activity in all papaya cultivars was comparable to the most tolerant soybean line. The zone of highest activity was the apical 10 mm of roots. These results indicate that papaya roots are highly efficient in induced Fe reductase activity. The highest activity in root tips underscores the importance of maintaining a healthy, continually growing root system with numerous growing points when culturing papaya in alkaline substrates.

Sign in / Sign up

Export Citation Format

Share Document