scholarly journals COVID-19 and Herpes Simplex Virus Infection: A Cross-Sectional Study

Cureus ◽  
2021 ◽  
Author(s):  
Mohammed Shanshal ◽  
Hayder Saad Ahmed
1990 ◽  
Vol 162 (2) ◽  
pp. 306-312 ◽  
Author(s):  
J. J. Gibson ◽  
C. A. Hornung ◽  
G. R. Alexander ◽  
F. K. Lee ◽  
W. A. Potts ◽  
...  

2003 ◽  
Vol 35 (8) ◽  
pp. 498-502 ◽  
Author(s):  
Petra Tunbäck ◽  
Tomas Bergström ◽  
Ann-sofi Andersson ◽  
Per Nordin ◽  
Ingela Krantz ◽  
...  

2021 ◽  
Author(s):  
Mohammed Shanshal ◽  
Hayder Saad Ahmed

Background Despite being variable and poorly characterized, the reported cutaneous manifestations of COVID-19 are of increasing concern. Aim of the Study This study aimed to assess the prevalence and possible association between COVID-19 and herpes simplex virus (HSV) infection. Patients and methods A 9-item questionnaire was sent to 120 PCR-confirmed COVID-19 patients with a response rate of 66.67%. This cross-sectional observational study included 80 patients with mild to moderate COVID-19 infection who did not require hospitalization or steroid therapy. Results One or more HSV infections were observed in 28 patients (35%) with COVID-19 infection, including 10 males (35.7%) and 18 females (64.29%). Of the 28 patients, fever was reported in 17 patients (75%) during COVID-19. Most of the respondents (78%) described a single HSV reactivation, 14.29% had 2 attacks, and 7.14% experienced 3 attacks. Compared to previous non-COVID-19 related HSV reactivation, the COVID-19 related attacks were more severe in 12 patients (42.85%), equally severe in 5 patients (17.85%) and less severe in 1 patient (3.57%). Interestingly, 10 patients (35.71%) developed an initial symptomatic HSV attack during COVID-19 infection. Conclusions This study demonstrated a possible association between COVID-19 infection and primary HSV infection and/or reactivation. The COVID-19 direct neuronal effect in addition to COVID-19 related psychological stress, fever and immunological dysregulation could play a potential role.


2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Seyed Ali Dehghan Manshadi ◽  
Sharif Teimourian ◽  
Arash Seifi ◽  
Zoha Alinejadi ◽  
Nahid Sarahian ◽  
...  

Vaccine ◽  
2013 ◽  
Vol 31 (44) ◽  
pp. 5067-5074 ◽  
Author(s):  
Carlos Conde-Glez ◽  
Eduardo Lazcano-Ponce ◽  
Rosalba Rojas ◽  
Rodrigo DeAntonio ◽  
Luis Romano-Mazzotti ◽  
...  

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