scholarly journals Ventricular Septal Defect in Delayed Presentation of ST-Elevation Myocardial Infarction (STEMI) Secondary to COVID-19 Pandemic

Cureus ◽  
2021 ◽  
Author(s):  
Pujon Purkayastha ◽  
Muhammad J Iftikhar ◽  
Maciej Kostrubiec
2017 ◽  
Vol 7 (2) ◽  
pp. 230-234
Author(s):  
Lilia M. Sierra-Galan ◽  
Angel L. Alberto-Delgado ◽  
Ana-Camila Flores-Ventura ◽  
Eugenio A. Ruesga-Zamora ◽  
Raquel Mendoza-Aguilar ◽  
...  

2020 ◽  
Vol 28 (5) ◽  
pp. 266-272
Author(s):  
Ashish Mishra ◽  
Jayesh Prajapati ◽  
Gajendra Dubey ◽  
Iva Patel ◽  
Mukesh Mahla ◽  
...  

Background Fibrinolytic therapy is an important reperfusion strategy, especially when primary percutaneous coronary interventions cannot be offered to ST-elevation myocardial infarction patients. Given that failed reperfusion after fibrinolytic therapy is common, it is pragmatic that the predictors, outcomes, and angiographic profiles of patients with failed thrombolysis are carefully scrutinized. Methods We prospectively studied clinical variables and outcomes over 30 months in 243 ST-elevation myocardial infarction patients who received fibrinolytics as primary treatment. Logistic regression analysis was used to identify predictors of failed thrombolysis. Results Failed thrombolysis occurred in 38.68% of patients with a mean window period of 6.58 ± 1.42 h, and 55.32% of patients with failed thrombolysis had Killip class >I on presentation. Risk factors such as diabetes mellitus (55.32%), dyslipidemia (60.64%) and obesity (77.66%) were frequently associated with failed thrombolysis; 73.40% of patients with failed thrombolysis had Thrombolysis in Myocardial Infarction flow grade 0/1 in the infarct-related artery, and 58.51% of such patients needed a rescue percutaneous coronary intervention. The mean Thrombolysis in Myocardial Infarction risk score was 5.46 ± 2.77 in failed thrombolysis patients, with mortality of 4.25% at the 6-month follow-up. Conclusion Non-resolution of presenting symptoms and ST changes on electrocardiography at 90 min served as the earliest indicators of failed thrombolysis, with a significant angiographic correlation. Clinical variables such as delayed presentation (>6 h), dyspnea, Killip class >I, cardiogenic shock, Thrombolysis in Myocardial Infarction score, and conventional risk factors including diabetes mellitus, dyslipidemia, and obesity represented cluster of predictors of failed thrombolysis.


2014 ◽  
Vol 41 (6) ◽  
pp. 613-619 ◽  
Author(s):  
Maria D. Baldasare ◽  
Mark Polyakov ◽  
Glenn W. Laub ◽  
Joseph T. Costic ◽  
Daniel J. McCormick ◽  
...  

Post-myocardial infarction ventricular septal defect is a devastating complication of ST-elevation myocardial infarction. Although surgical intervention is considered the gold standard for treatment, it carries high morbidity and mortality rates. We present 2 cases that illustrate the application of percutaneous closure of a post-myocardial infarction ventricular septal defect: the first in a patient who had undergone prior surgical closure and then developed a new shunt, and the second as a bridge to definitive surgery in a critically ill patient.


2015 ◽  
Vol 27 (4) ◽  
pp. 316
Author(s):  
Mohammed Abbas T. Albrahim ◽  
Amjad Ahmed ◽  
Abdulrahman Anwar Alwakeel ◽  
Faisal Muthana Hijji ◽  
Mohammed Abbas T. Albrahim

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