scholarly journals Concurrent Chemoradiation With 5-Fluorouracil and Mitomycin in Squamous Cell Carcinoma of the Rectum

Cureus ◽  
2021 ◽  
Author(s):  
Ashish K Sethi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Concurrent Chemoradiation ◽  
Carcinoma Of The Rectum

Lower pretreatment hemoglobin status and treatment breaks in locally advanced head and neck squamous cell carcinoma during concurrent chemoradiation

2020 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Karthikeyan Perumal ◽  
RajeshKar Narayanasamy ◽  
RM Muthusekar ◽  
SathiamoorthyPattanam Nagalingam ◽  
Sendil Thyagarajan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Locally Advanced ◽  
Neck Squamous Cell Carcinoma ◽  
Concurrent Chemoradiation ◽  
Advanced Head

Squamous cell carcinoma of the rectum

2020 ◽  
Vol 13 (10) ◽  
pp. e236256
Author(s):  
Deep Chakrabarti ◽  
Sumaira Qayoom ◽  
Naseem Akhtar ◽  
Rajeev Gupta
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Squamous Metaplasia ◽  
Gastrointestinal Cancers ◽  
Multidisciplinary Team Meeting ◽  
Carcinoma Of The Rectum ◽  
Planning Treatment ◽  
Tumour Location ◽  
Colon And Rectum

Lower gastrointestinal cancers are commonly adenocarcinoma in the colon and rectum, and of squamous cell histology in the anal canal. Squamous cell carcinoma of the rectum is a rare disease attributable to squamous metaplasia in the rectum. The tumour location and histopathology should both serve as indicators to planning treatment, and a robust multidisciplinary team meeting forms the backbone of such decisions.

Phase II randomized study comparing concurrent chemoradiation versus neoadjuvant chemotherapy followed by chemoradiation in locally advanced unresectable squamous cell carcinoma of esophagus.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e15138-e15138
Author(s):  
Pritee Baburao Chaudhari ◽  
Subhash Chander ◽  
B. K. Mohanti ◽  
Atul Sharma ◽  
Jaspreet Kaur ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Neoadjuvant Chemotherapy ◽  
Cell Carcinoma ◽  
Phase Ii ◽  
Squamous Cell ◽  
Locally Advanced ◽  
Post Treatment ◽  
Concurrent Chemoradiation ◽  
Weekly Paclitaxel ◽  
Carcinoma Of Esophagus

e15138 Background: A significant number of patients diagnosed with esophageal cancer (EC) presents with locally advanced disease. Nonsurgical curative therapy for unresectable EC has limited outcome. Methods: Phase II randomized control trial to assess early locoregional response (LRR) to neoadjuvant chemotherapy (NACT) followed by concurrent chemoradiation (CRT) versus definitive CRT in surgically unresectable squamous cell carcinoma of esophagus (ESCC). A total of 30 patients were randomly assigned to two arms. Arm 1: 2 cycles NACT regimen of 5-fluorouracil (750mg/m2 D1-4) and cisplatin (80mg D1-2) followed by CRT, radiation of 56Gy/ 28 Fr concurrent with weekly paclitaxel 50mg/m2 and carboplatin AUC2. Arm2: CRT; consisting of radiation 56Gy/28Fr and weekly paclitaxel 50mg/m2 and carboplatin AUC2. All the patients were followed till 6 months post treatment. LRR assessment was done at 1, 3 and 6 months post treatment. Wilcoxon multivariate analysis was carried out and difference of the factors were assessed by chi square test (x2 p<0.05). Results: Mean age in two arms were 52 and 54 years respectively. The study had median follow up of 6.6 months. Conclusions: In unresectable EC, CRT showed higher LRR, treatment completion and lesser toxicity compared to NACT combined with CRT. In this pilot cohort of locally advanced unresectable EC paclitaxel and carboplatin combined with radiotherapy has good tolerance and compliance. [Table: see text]

scholarly journals SQUAMOUS CELL CARCINOMA OF THE RECTUM

1951 ◽  
Vol 133 (2) ◽  
pp. 283-285 ◽  
Author(s):  
Joseph P. OʼBrien ◽  
Donald J. Meehan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Carcinoma Of The Rectum
Sign in / Sign up

Export Citation Format

Share Document