scholarly journals Can Subacute Thyroiditis Be a Cause of Fever of Unknown Origin?

Cureus ◽  
2021 ◽  
Author(s):  
Bhagyalakshmi Satyanarayan ◽  
Anupama Sahu ◽  
Satish K Prasad ◽  
Sarita Kumari
Author(s):  
Ahmad Housin ◽  
Marc P Pusztaszeri ◽  
Michael Tamilia

Summary Fever of unknown origin is a commonly encountered medical problem. Most common causes include infections, malignancy, and connective tissue diseases. Endocrine causes are rare but are well documented. While fever is common in some endocrine disorders, fever of unknown origin as the sole presenting feature is very rare. We describe a case report of a 63-year-old male who presents with fever of unknown origin. Imaging and biopsy results confirmed the diagnosis of subacute thyroiditis. He was started on prednisone with a good response. We conclude that subacute thyroiditis should be considered in the work up of fever of unknown origin even in the absence of classical signs and symptoms. Learning points Fever of unknown origin is a rare sole presentation of subacute thyroiditis. The classic signs and symptoms may not be manifest at the time of presentation. Normal thyroid function tests and elevated markers of inflammation often make infections, malignancy and autoinflammatory conditions the prime consideration. Imaging of the thyroid gland may point to a morphologic aberration and prompt a thyroid biopsy. After exclusion of infection, a rapid response to steroids may be both diagnostic and therapeutic.


2017 ◽  
Vol 17 (1) ◽  
pp. 86-87 ◽  
Author(s):  
Fatima Amar Bahowairath ◽  
Nicholas Woodhouse ◽  
Samir Hussain ◽  
Mujahid Al Busaidi

2013 ◽  
Vol 84 (5) ◽  
pp. 733 ◽  
Author(s):  
Jong Ho Kim ◽  
Kwi Hyun Bae ◽  
Yeon Kyung Choi ◽  
In Gyoon Ha ◽  
Keun Gyu Park ◽  
...  

Heart & Lung ◽  
2005 ◽  
Vol 34 (2) ◽  
pp. 147-151 ◽  
Author(s):  
Burke A. Cunha ◽  
Marjorie Thermidor ◽  
Sowjanya Mohan ◽  
Ageliki S. Valsamis ◽  
Diane H. Johnson

2000 ◽  
Vol 93 (9) ◽  
pp. 926-929 ◽  
Author(s):  
BRENDAN M. WEISS ◽  
MATTHEW J. HEPBURN ◽  
DENNIS P. MONG

2010 ◽  
Vol 64 (1) ◽  
pp. 97-98 ◽  
Author(s):  
G. N. Karachalios ◽  
K. Amantos ◽  
K. V. Kanakis ◽  
A. Deliousis ◽  
I. G. Karachaliou ◽  
...  

2000 ◽  
Vol 93 (9) ◽  
pp. 926-929 ◽  
Author(s):  
BRENDAN M. WEISS ◽  
MATTHEW J. HEPBURN ◽  
DENNIS P. MONG

2020 ◽  
Author(s):  
Abir Bou Khalil ◽  
Walid Alam ◽  
Abdul Rahman Bizri

Abstract Background: Subacute thyroiditis (SAT) is a rare but well-established cause of fever of unknown origin (FUO) and should be considered in the differential of patients presenting with fever of unknown origin. Few reports in the English literature where published about Subacute thyroiditis manifesting as fever of unknown origin. Subacute thyroiditis may be hard to detect by physicians based on history and physical exam if the systemic manifestations are absent. Methods: An observational retrospective review of 375 charts of patients presenting with thyroiditis to the American University of Beirut Medical Center between January 1995 and June 2015. Inclusion criteria included patients who have subacute thyroiditis based on the American Thyroid Association and American Association of Clinical Endocrinologists guidelines and fever of unknown origin based on Durak and Street’s definition. All patients that do not fit both inclusion criteria were excluded. The patients’ demographics, clinical presentation, laboratory and diagnostic findings, and treatments used were analyzed. Results: 375 charts were reviewed. 31 patients had SAT of which 13 patients had fever of unknown origin before diagnosing subacute thyroiditis. 13 charts were not available for screening. Symptoms of hyperthyroidism including palpitations, neck tenderness and weight loss were not present in all patients. Elevated markers of inflammation mainly ESR and CRP were raised when screened for.Conclusions: The diagnosis of subacute thyroiditis should be considered in patients presenting with fever of unknown origin and elevated inflammatory markers, even in the absence of suggestive clinical symptoms.


2010 ◽  
Vol 16 (2) ◽  
pp. 88-89 ◽  
Author(s):  
Dimitrios Vassilopoulos ◽  
Konstantinos Sialevris ◽  
Sophia Malahtari ◽  
Melanie Deutsch ◽  
Spilios Manolakopoulos ◽  
...  

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