scholarly journals Pet Therapy as a Nonpharmacological Treatment Option for Neurological Disorders: A Review of the Literature

Cureus ◽  
2021 ◽  
Author(s):  
Catherine M Boldig ◽  
Nitin Butala
Keyword(s):  
Treatment Option ◽  
Neurological Disorders ◽  
Pet Therapy ◽  
Review Of The Literature ◽  
Nonpharmacological Treatment

scholarly journals Botulinum Toxin in Movement Disorders: An Update

Toxins ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 42
Author(s):  
Charenya Anandan ◽  
Joseph Jankovic
Keyword(s):  
Botulinum Toxin ◽  
Movement Disorders ◽  
Neurological Disorders ◽  
Active Drug ◽  
Therapeutic Agents ◽  
Therapeutic Modality ◽  
Review Of The Literature ◽  
Pilot Studies ◽  
The Us ◽  
Novel Applications

Since its initial approval in 1989 by the US Food and Drug Administration for the treatment of blepharospasm and other facial spasms, botulinum toxin (BoNT) has evolved into a therapeutic modality for a variety of neurological and non-neurological disorders. With respect to neurologic movement disorders, BoNT has been reported to be effective for the treatment of dystonia, bruxism, tremors, tics, myoclonus, restless legs syndrome, tardive dyskinesia, and a variety of symptoms associated with Parkinson’s disease. More recently, research with BoNT has expanded beyond its use as a powerful muscle relaxant and a peripherally active drug to its potential central nervous system applications in the treatment of neurodegenerative disorders. Although BoNT is the most potent biologic toxin, when it is administered by knowledgeable and experienced clinicians, it is one of the safest therapeutic agents in clinical use. The primary aim of this article is to provide an update on recent advances in BoNT research with a focus on novel applications in the treatment of movement disorders. This comprehensive review of the literature provides a critical review of evidence-based clinical trials and highlights recent innovative pilot studies.

The Korsakov Syndrome in Spontaneous Subarachnoid Haemorrhage

1953 ◽  
Vol 99 (416) ◽  
pp. 521-530 ◽  
Author(s):  
John N. Walton
Keyword(s):  
Subarachnoid Haemorrhage ◽  
Neurological Disorders ◽  
Review Of The Literature ◽  
Case Histories ◽  
Actual Case ◽  
Mental Symptoms ◽  
Symptom Complex ◽  
Excellent Description ◽  
The Subject ◽  
Neurological Conditions

The amnestic-confabulatory symptom-complex to which the eponymous title of Korsakov's syndrome is usually given was probably first described by the Swedish physician Magnus Huss (1807–90), who spent the greater part of his lifetime in the study of alcoholism. There is, however, no doubt that Korsakov's (1890) paper on the subject gave an excellent description of the syndrome, and stressed the fact that whereas it often developed in patients with alcoholism and polyneuritis, numerous other metabolic and neurological disorders could be complicated by the characteristic mental changes. Indeed, in Korsakov's (1890) own series of cases alcoholics were in the minority. One of the neurological conditions in which the syndrome has been described significantly often is spontaneous subarachnoid haemorrhage. The first reports of the association were probably those of Flatau (1918 and 1921), and it was discussed in some detail by Goldflam (1923) and Herman (1925 and 1926). Each of these authors described the mental symptoms exhaustively but gave no actual case-histories; the first fully documented cases in the literature were the two reported by Hall (1929). Single cases have since been described by Cubitt (1930), Popow (1930) and Kulkow (1935), and in 1939 Tarachow gave an extensive review of the literature and reported an additional 3 cases. It is remarkable that since 1939 the association has received little attention, although it has been mentioned by Sands (1941) and Meadows (1951).

scholarly journals Surgery results in low relapse and progression rates in extramedullary plasmacytoma of the head and neck: A case cohort and review of the literature

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Matevz Skerget ◽  
Tadej Dovsak ◽  
Gregor Kos ◽  
Samo Zver
Keyword(s):  
Multiple Myeloma ◽  
Local Recurrence ◽  
Head And Neck ◽  
Treatment Option ◽  
Local Control ◽  
Extramedullary Plasmacytoma ◽  
Initial Evaluation ◽  
Review Of The Literature

Extramedullary plasmacytoma of the head and neck is a rare indolent neoplasm. Radiotherapy is often the preferred treatment option with excellent local control and survival. The risk of local recurrence or transformation to multiple myeloma is 10- 30%. In our case-cohort, thorough, sensitive initial evaluation for disseminated clonal disease and the incorporation of surgery led to excellent results with no recurrences or systemic progression.

scholarly journals Treatment Option for Abernethy Malformation—Two Cases Report and Review of the Literature

2020 ◽  
Vol 8 ◽  
Author(s):  
Yuese Lin ◽  
Xuandi Li ◽  
Shujuan Li ◽  
Hongjun Ba ◽  
Huishen Wang ◽  
...  
Keyword(s):  
Treatment Option ◽  
Review Of The Literature ◽  
Abernethy Malformation

scholarly journals A Case Report of Urinary Bladder Carcinosarcoma and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
Christos Zachariadis ◽  
Ioannis Efthimiou ◽  
Stylianos Giannakopoulos ◽  
Athanasios Bantis ◽  
Alexandra Giatromanolaki ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Urinary Bladder ◽  
Treatment Option ◽  
Transurethral Resection ◽  
Case Reports ◽  
Review Of The Literature ◽  
Small Series ◽  
Radiotherapy Alone ◽  
Aggressive Tumors

Carcinosarcoma of the bladder is an unusual tumour characterized by a combination of malignant epithelial and soft tissue elements. Most of the reported cases have been case reports or small series. Optimal treatment is uncertain. We herein report our experience in such a case treated with transurethral resection followed by radiotherapy with adverse final outcome. Treatment of bladder carcinosarcomas should be aggressive and multimodal but optional treatment is still unknown. Radiotherapy alone is insufficient as a treatment option of these aggressive tumors.

Imatinib mesylate as a novel treatment option for hypereosinophilic syndrome: two case reports and a comprehensive review of the literature

2005 ◽  
Vol 85 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Antonia M. S. Müller ◽  
Uwe M. Martens ◽  
Silke C. Hofmann ◽  
Leena Bruckner-Tuderman ◽  
Roland Mertelsmann ◽  
...  
Keyword(s):  
Imatinib Mesylate ◽  
Treatment Option ◽  
Case Reports ◽  
Hypereosinophilic Syndrome ◽  
Review Of The Literature ◽  
Comprehensive Review ◽  
Novel Treatment

scholarly journals Omalizumab Treatment in Chronic Spontaneous Urticaria During Pregnancy: Report of A Case and Review of the Literature

2021 ◽  
Vol 19 (2) ◽  
pp. 114-117
Author(s):  
Andac Salman ◽  
Meryem Aktaş
Keyword(s):  
Pregnant Woman ◽  
Cohort Studies ◽  
Effective Treatment ◽  
Treatment Option ◽  
Congenital Abnormalities ◽  
Chronic Spontaneous Urticaria ◽  
Review Of The Literature ◽  
Effective Treatment Option ◽  
Increased Risk

ABSTRACT Omalizumab is a safe and effective treatment option for chronic spontaneous urticaria (CSU). Although cohort studies in patients with asthma show no increased risk of congenital abnormalities, very little data exist in the literature regarding the use of omalizumab for CSU during pregnancy. Herein, the safe and successful use of omalizumab updosing in a pregnant woman with CSU along with a review of the published literature is presented. Keywords: Chronic spontaneous urticaria, omalizumab, pregnancy, updosing

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