scholarly journals Atypical Burkholderia Cepacia Resistance to Ceftazidime/Avibactam and Co-trimoxazole: A Case of Open Wound Contamination and Persistent Bacteremia

Cureus ◽  
2021 ◽  
Author(s):  
Fidelis Uwumiro ◽  
Ehizogie Edigin ◽  
Victory Okpujie
Keyword(s):  
Burkholderia Cepacia ◽  
Open Wound ◽  
Wound Contamination ◽  
Persistent Bacteremia

scholarly journals Cellulitis caused by the Burkholderia cepacia complex associated with contaminated chlorhexidine 2% scrub in five domestic cats

2018 ◽  
Vol 30 (5) ◽  
pp. 763-769 ◽  
Author(s):  
Jessica K. Wong ◽  
Lara C. Chambers ◽  
Elizabeth J. Elsmo ◽  
Tiffany L. Jenkins ◽  
Elizabeth W. Howerth ◽  
...  
Keyword(s):  
Burkholderia Cepacia ◽  
Wound Care ◽  
Clinical Signs ◽  
Burkholderia Cepacia Complex ◽  
Empiric Antibiotic Therapy ◽  
Human Pathogens ◽  
Open Wound ◽  
Source Of Infection ◽  
Empiric Antibiotic ◽  
Antiseptic Solutions

Isolates of the Burkholderia cepacia complex (BCC) are known as plant and human pathogens. We describe herein BCC infections as the cause of subcutaneous abscesses and purulent cellulitis in 5 cats. All cats were presented with an open wound, and 4 received standard wound care and empiric antibiotic therapy. Despite treatment, clinical signs worsened in 4 cats. Isolates of the BCC were obtained from all 5 cases. Two cats were submitted for postmortem examination. Subcutaneous abscesses with draining fistulas were observed. Histopathology revealed severe, pyogranulomatous cellulitis with intralesional gram-negative bacilli. Based on susceptibility results, the other 3 cats were administered effective antibiotics and recovered without complications. The BCC was cultured from the 2% chlorhexidine surgical scrub solution used in the clinic, suggesting the source of infection for 4 of 5 cats. Given the ability to grow in antiseptic solutions, the extra steps required to culture from antiseptics, and innate multidrug resistance, the BCC poses a challenge to both detect and treat. Although the BCC causes disease almost exclusively in humans with cystic fibrosis or immunodeficiency, the bacteria should also be a differential for nosocomial infections in veterinary patients.

Bi-microbial Healthcare-Associate Endocarditis caused by Enterococcus faecalis and Burkholderia cepacia: A Case Report and literature review

2020 ◽  
Vol 02 ◽  
Author(s):  
Masood Ghori ◽  
Nadya O. Al Matrooshi ◽  
Samir Al Jabbari ◽  
Ahmed Bafadel ◽  
Gopal Bhatnagar
Keyword(s):  
Case Report ◽  
Infective Endocarditis ◽  
Literature Review ◽  
Enterococcus Faecalis ◽  
Surgical Management ◽  
Burkholderia Cepacia ◽  
Clinical Presentation ◽  
Complicated Course ◽  
Healthcare Associated ◽  
Echocardiographic Findings

: Infective Endocarditis (IE), a known complication of hemodialysis (HD), has recently been categorized as Healthcare-Associated Infective Endocarditis (HAIE). Single pathogen bacteremia is common, polymicrobial endocardial infection is rare in this cohort of the patients. We report a case of endocarditis caused by Enterococcus faecalis (E. faecalis) and Burkholderia cepacia (B. cepacia), a first ever reported combination of a usual and an unusual organism, respectively, in a patient on HD. Clinical presentation of the patient, its complicated course ,medical and surgical management ,along with microbial and echocardiographic findings is presented herein. The authors believe that presentation of this case of HAIE may benefit and contribute positively to cardiac science owing to the rare encounter of this organism as a pathogen in infective endocarditis and the difficulties in treating it.

scholarly journals 2329. Preliminary Safety and Effectiveness of Whole-Body MRI in Pediatric Patients With Persistent Bacteremia or Febrile Illness

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S692-S692
Author(s):  
Edwin Hayes ◽  
Lindsay Miranda ◽  
Anna-Kathryn Burch ◽  
Matthew Marcus ◽  
Helmut Albrecht ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Febrile Illness ◽  
Whole Body ◽  
Whole Body Mri ◽  
Persistent Bacteremia
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