scholarly journals Malignant Catatonia Versus Neuroleptic Malignant Syndrome

Cureus ◽  
2021 ◽  
Author(s):  
Saral Desai ◽  
Tinu Hirachan ◽  
Anca Toma ◽  
Adela Gerolemou
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Malignant Catatonia

scholarly journals Hyperthermia syndromes in psychiatry

2009 ◽  
Vol 15 (3) ◽  
pp. 181-191 ◽  
Author(s):  
Niraj Ahuja ◽  
Andrew J. Cole
Keyword(s):  
Drug Treatment ◽  
Neuroleptic Malignant Syndrome ◽  
Electroconvulsive Therapy ◽  
Serotonin Syndrome ◽  
Systematic Approach ◽  
Psychiatric Patients ◽  
Initial Diagnosis ◽  
Malignant Hyperpyrexia ◽  
Malignant Catatonia

SummaryPresence of fever in psychiatric patients may signify a number of potentially fatal conditions. Several of these are related to treatments (e.g. neuroleptic malignant syndrome with antipsychotics, serotonin syndrome with serotonergic antidepressants, and malignant hyperpyrexia with anaesthesia used for administration of electroconvulsive therapy) or exacerbated by them (e.g. malignant catatonia with antipsychotics). New classes of drug treatment may be changing the epidemiology of these disorders. We suggest that an initial diagnosis of hyperthermia syndrome is clinically useful as there are some important commonalities in treatment. We outline a systematic approach to identify a particular subtype of hyperthermia syndrome and the indications for more specific treatments where available.

Neuroleptic malignant syndrome and delirious mania as malignant catatonia in autism: prompt relief with electroconvulsive therapy

2015 ◽  
Vol 132 (4) ◽  
pp. 319-320 ◽  
Author(s):  
L. Wachtel ◽  
E. Commins ◽  
M. Park ◽  
N. Rolider ◽  
R. Stephens ◽  
...  
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Electroconvulsive Therapy ◽  
Malignant Catatonia

Recognition and Treatment of the Catatonic Syndrome

1997 ◽  
Vol 12 (3) ◽  
pp. 135-147 ◽  
Author(s):  
Gregory Fricchione ◽  
George Bush ◽  
Manish Fozdar ◽  
Andrew Francis ◽  
Max Fink
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Mental Disorders ◽  
Neuroleptic Malignant Syndrome ◽  
Differential Diagnoses ◽  
Suggested Approach ◽  
Syndrome Diagnosis ◽  
History Of ◽  
Catatonic Syndrome ◽  
Malignant Catatonia

We define the catatonic syndrome and review the history of the concept of catatonia, including its recent acceptance as a syndrome. Diagnosis of the catatonic syndrome, with its associated extensive differential diagnoses related to systemic and mental disorders, is addressed. Catatonia is related to variants of the syndrome, such as lethal (malignant) catatonia and the neuroleptic malignant syndrome (NMS). Medical sequelae of these conditions are outlined. The literature on the treatment of the catatonic syndrome is reviewed, and a suggested approach to treatment and management of catatonic patients in the intensive care unit is provided. An hypothesis regarding the neuropathophysiological basis for the syndrome is also offered.

Catatonia, Malignant Catatonia, and Neuroleptic Malignant Syndrome

2013 ◽  
Vol 9 (2) ◽  
pp. 111-119 ◽  
Author(s):  
Stephan C. Mann ◽  
Stanley N. Caroff ◽  
Gabor S. Ungvari ◽  
E. Cabrina Campbell
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Malignant Catatonia

Clozapine Withdrawal-Induced Malignant Catatonia or Neuroleptic Malignant Syndrome

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Zsuzsanna Belteczki ◽  
Julia Ujvari ◽  
Peter Dome
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Clozapine Withdrawal ◽  
Malignant Catatonia

Malignant catatonia and neuroleptic malignant syndrome: How different/similar are they?

2016 ◽  
Vol 33 (S1) ◽  
pp. S640-S640 ◽  
Author(s):  
P. Sales ◽  
M. Bernardo ◽  
A. Lopes ◽  
E. Trigo
Keyword(s):  
Supportive Care ◽  
Neuroleptic Malignant Syndrome ◽  
Specific Treatment ◽  
Hemodynamic Instability ◽  
Psychotic Symptoms ◽  
Muscle Rigidity ◽  
Life Threatening ◽  
History Of ◽  
Competing Interest ◽  
Malignant Catatonia

IntroductionCatatonia is a neuropsychiatric syndrome that appears in medical, neurological or psychiatric conditions. There are presentation variants: “malignant catatonia” (MC) subtype shares many characteristics with the neuroleptic malignant syndrome (NMS), possibly reflecting common pathophysiology.Objectives/methodsWe present a clinical vignette and review the literature available on online databases about MC/NMS.ResultsWe present a man, 41-years-old, black ethnicity, with no relevant medical history. He had two previous episodes compatible with brief psychosis, the last one in 2013, and a history of adverse reactions to low doses of antipsychotics. Since the last episode he was asymptomatic on olanzapine 2.5 mg id. He acutely presented to the Emergency Room with mutism, negativism, immobility and delusional speech, similar to the previous episodes mentioned and was admitted to a psychiatric infirmary, where his clinical condition worsened, showing muscle rigidity, hemodynamic instability, leukocytosis, rhabdomyolysis and fever. Supportive care was provided, olanzapine was suspended and electroconvulsive therapy (ECT) was initiated. After two months, he was discharged with no psychotic symptoms. He is still under ECT and no antipsychotic medication was reintroduced.Discussion/conclusionMany studies suggest that clinical or laboratory tests do not distinguish MC from NMS and that they are the same entity. These two conditions are life-threatening and key to treatment is a high suspicion level. There is no specific treatment; supportive care and stopping involved medications are the most widely used measures. ECT is a useful alternative to medication.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Use of Dantrolene and Ativan to Treat Overlapping Diagnosis NMS Versus Malignant Catatonia Case Report

2021 ◽  
Author(s):  
Dynela Garcia-Baran ◽  
Sam Collier ◽  
Alejandro Ortiz
Keyword(s):  
Case Report ◽  
Hospital Stay ◽  
Neuroleptic Malignant Syndrome ◽  
Second Generation ◽  
Treatment Guidelines ◽  
Manic Episode ◽  
Type I ◽  
Second Generation Antipsychotics ◽  
Simultaneous Intervention ◽  
Malignant Catatonia

Abstract We present a case report of a patient who developed symptoms resembling malignant catatonia and neuroleptic malignant syndrome. Suspicion of neuroleptic malignant syndrome arose after treatment over his course of hospital stay with three different second-generation antipsychotics for a first-time bipolar type I manic episode. After a hospital stay of 5 days, the patient developed symptoms that could be interpreted as malignant catatonia or neuroleptic malignant syndrome. Administration of antipsychotics was immediately ceased, and the patient was transferred to the ICU where he was treated with dantrolene and higher dosages of Ativan. The patient improved after simultaneous intervention for both possible diagnoses. After approximately one month, quetiapine, one of the second generation antipsychotics previously prescribed, was restarted with good results and no reoccurrence of NMS or malignant catatonia. This case illustrates the potential dilemma faced when differentiation between the two obscure diagnoses is necessary. Diagnosis is typically established through clinical observation and monitoring of symptom evolution after the administration of neuroleptics. The treatment algorithms for each diagnosis vary as can the respective outcomes. Our case also highlights the dearth of research available on distinguishing neuropathologic psychiatric disorders from pathophysiologic psychomotor syndromes. It also focuses on the need for sound diagnostic scoring scales that will clarify the diagnostic picture as well as treatment guidelines to ensure best outcomes.

scholarly journals Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose

2016 ◽  
Vol 38 (4) ◽  
pp. 344-347 ◽  
Author(s):  
Kiran K. Kumar ◽  
Swapna Bondade ◽  
Fiaz Ahmed Sattar ◽  
Niharika Singh
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Malignant Catatonia

Early introduction of clozapine after neuroleptic malignant syndrome may prevent malignant catatonia: A case report

2017 ◽  
Vol 27 (1) ◽  
pp. 91-92 ◽  
Author(s):  
G. van Rooijen ◽  
M. Strypet ◽  
A. Maat ◽  
D.S Scheepens ◽  
M.S. Oudijn ◽  
...  
Keyword(s):  
Case Report ◽  
Neuroleptic Malignant Syndrome ◽  
Early Introduction ◽  
Malignant Catatonia

scholarly journals Catatonic Symptoms Appearing before Autonomic Symptoms Help Distinguish Neuroleptic Malignant Syndrome from Malignant Catatonia

2016 ◽  
Vol 55 (19) ◽  
pp. 2893-2897 ◽  
Author(s):  
Takayuki Komatsu ◽  
Tomohisa Nomura ◽  
Hiroki Takami ◽  
So Sakamoto ◽  
Keiko Mizuno ◽  
...  
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Autonomic Symptoms ◽  
Malignant Catatonia
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