scholarly journals Acquired Gerbode Defect in a Patient With Infective Endocarditis of Bicuspid Aortic Valve

Cureus ◽  
2021 ◽  
Author(s):  
Mohammed Mahdi ◽  
Muhammet Özer ◽  
Bipinpreet Nagra ◽  
Patrick Aufiero ◽  
Bharat Kantharia
2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Nicholas Sunderland ◽  
Ahmed El-Medany ◽  
Justin Temporal ◽  
Laura Pannell ◽  
Gemina Doolub ◽  
...  

Abstract Background  The Gerbode defect is a rare abnormal communication between the left ventricle (LV) and right atrium (RA). The lesion is either congenital or acquired. Acquired defects are largely iatrogenic or infective in origin. We present two cases of acquired Gerbode defects with similar clinical presentations but very different outcomes. Case summaries Patient 1 A 64-year-old male presented with features of decompensated cardiac failure and a low-grade temperature. Dehiscence of a recently implanted bioprosthetic aortic valve and high-velocity LV to RA jet (Gerbode defect) was found on echocardiography. Blood cultures grew Staphylococcus warneri and the diagnosis of infective endocarditis was established. The patient was treated with intravenous antibiotics and the aortic valve and Gerbode defect were successfully surgically repaired. Patient 2 An 81-year-old male presented after being found on the floor at home. On admission, he was clinically septic with evidence of decompensated heart failure. No clear infective focus was initially found. Transthoracic echocardiography revealed severe left ventricular impairment, with a normal bioprosthetic aortic valve. He was treated with intravenous antibiotics, but later deteriorated with evidence of embolic phenomena. Repeat echocardiography revealed a complex infective aortic root lesion with bioprosthetic valve dehiscence and flow demonstrated from the LV to RA. Unfortunately, the patient succumbed to the infection and cardiac complications. Discussion  The Gerbode defect is a rare but important complication of infective endocarditis and valve surgery. Care needs to be taken to assess for Gerbode defect shunts on echocardiogram, especially in the context of previous cardiac surgery.


2019 ◽  
pp. 1-2
Author(s):  
Giuseppa Caccamo ◽  
Giuseppe Vitale ◽  
Emerico Ballo ◽  
Cinzia Nugara ◽  
Silvia Sarullo ◽  
...  

Infective endocarditis is a disease associated with high mortality and severe complications. We report a case of a young shepherd affected by valvular endocarditis on a bicuspid aortic valve, complicated by a pseudoaneurysm with periaortic abscess. Thanks to the use of multimodality diagnostic imaging (particular echocardiogram, Magnetic Risonance Imaging, Computed tomography-scan and coronary angiography), it was possible to make a correct diagnosis, in order to plan a tailored surgical strategy and to reduce the perioperative risks. The operation consisted of myocardial revascularization, closure of the annular pseudoaneurysm and aortic valve replacement with mechanical prosthesis. The patient maintained normal inflammation indices and was discharged at home in the absence of relevant clinical events. Infective endocarditis is a deadly disease. Multimodality imaging is crucial to clarify anatomical distorsions that can occur in complicated cases.


2006 ◽  
Vol 35 (3) ◽  
pp. 183-187
Author(s):  
Sawaka Tanabe ◽  
Kuniyoshi Tanaka ◽  
Akio Ihaya ◽  
Koichi Morioka ◽  
Takahiko Uesaka ◽  
...  

2021 ◽  
Vol 16 (5-6) ◽  
pp. 185-186
Author(s):  
Anto Stažić ◽  
Grgur Dulić ◽  
Sandra Makarović ◽  
Ivica Bošnjak ◽  
Nora Pušeljić ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
S. Kumar ◽  
S. Mahmood ◽  
A. Madras ◽  
A. Iyer

Abiotrophia defectiva is an uncommon and insidious yet destructive cause of infective endocarditis preferentially treated with penicillin/gentamicin and often requiring surgical treatment. A 60-year-old man with penicillin anaphylaxis history presented with fevers and a nonspecific constellation of symptoms. He was ultimately diagnosed with bicuspid aortic valve infective endocarditis based on blood cultures growing A.defectiva and echocardiographic evidence of bicuspid aortic valve, severe valvular regurgitation, and 5 × 7   mm vegetation. Aortic valve replacement and culture yielded penicillin-sensitive A.defectiva. After successful penicillin desensitization, antibiotic therapy was switched from vancomycin/gentamicin to benzylpenicillin. This is the first published case of penicillin desensitization in a patient with A.defectiva-associated infection. Penicillin desensitization, optimal antibiotic therapy, prompt aortic valve replacement, and close collaboration between cardiology and various other specialties were essential in achieving a positive outcome.


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