scholarly journals Gastroesophageal Reflux Disease in the Young Population and Its Correlation With Anxiety and Depression

Cureus ◽  
2021 ◽  
Author(s):  
Pooja Bai ◽  
Shehar Bano ◽  
Sameet Kumar ◽  
Priyanka Sachdev ◽  
Ahmed Ali ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Anxiety And Depression ◽  
Young Population

Effects of Anxiety and Depression in Patients With Gastroesophageal Reflux Disease

2015 ◽  
Vol 13 (6) ◽  
pp. 1089-1095.e1 ◽  
Author(s):  
Boudewijn F. Kessing ◽  
Albert J. Bredenoord ◽  
Caroline M.G. Saleh ◽  
André J.P.M. Smout
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Anxiety And Depression

scholarly journals Features of psychoemotional status and eating disorders in patients with gastroesophageal reflux disease and obesity

2021 ◽  
Vol 23 (5) ◽  
pp. 412-416
Author(s):  
Georgy L. Yurenev ◽  
◽  
Ekaterina M. Mironova ◽  
Natalia A. Sirota ◽  
Tamara V. Yureneva-Tkhorzhevskaya ◽  
...  
Keyword(s):  
Risk Factors ◽  
Eating Disorders ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Eating Behavior ◽  
Reflux Disease ◽  
Anxiety And Depression ◽  
Obese Patients ◽  
History Of ◽  
Depressive States

Background. Eating disorders, as well as features of the psychoemotional status as risk factors for obesity, patients with comorbid gastroesophageal reflux disease (GERD) and obesity in the modern literature are not sufficiently disclosed. Further study of these aspects may be one of the additional ways to improve the prognosis of the course of GERD, as well as the correction of the psychoemotional status of patients. Aim. To study the features of the course of GERD in concomitant obesity in the context of the peculiarities of the psychoemotional sphere, as well as to identify the types of eating disorders in this cohort of patients. Materials and methods. The study included 130 patients aged 24 to 72 years with complaints characteristic of the pathology of the upper digestive tract, who, along with a detailed analysis of complaints in order to verify the diagnosis and identify the features of the course of the disease, were tested with the Dutch Eating Behavior Questionnaire (DEBQ) and the hospital scale of anxiety and depression (HADS). Results. It was found that obese patients who had GERD less than 8 years ago were more likely to suffer from external and emotionogenic eating disorders, and the external type was more often associated with the male, and the emotionogenic type with the female sex. Whereas, in patients with obesity and a history of GERD for more than 8 years, the restrictive and emotionogenic types of eating disorders were relatively more often recorded. An increased level of anxiety in patients with GERD was noted, both against the background of obesity and without it, but those with comorbid pathology had a relatively higher score on the anxiety scale. Conclusion. Correction of eating behavior and signs of anxiety-depressive states in patients can open up new prospects for the fight against obesity. And this, in turn, can improve the prognosis of patients with GERD.

scholarly journals High resolution esophageal manometry and life exposure factors in non-cardiac chest pain patients with refractory gastroesophageal reflux disease

2019 ◽  
Author(s):  
Yuan Li ◽  
Peicong Lyu ◽  
Zhifeng Zhang ◽  
Liya Wang ◽  
Xiaoyu Sun ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chest Pain ◽  
High Resolution ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Esophageal Manometry ◽  
Therapeutic Strategies ◽  
Anxiety And Depression ◽  
Esophageal Sphincter

Abstract Background: Refractory gastroesophageal reflux disease (RGERD) is defined by the presence of troublesome GERD symptoms despite proton pump inhibitors (PPIs) treatments for 8-12 weeks. Non-cardiac chest pain (NCCP) is the most common atypical presentations. This study was aimed at clarifying the features of High Resolution Esophageal Manometry (HREM) and life exposure factors of NCCP in RGERD patients for guiding further therapeutic strategies. Methods: 83 RGERD patients were enrolled, in which 44 patients afflicted with NCCP as P group and 39 patients without NCCP as NP group. According to the endoscopy results, P group was further divided into reflux esophagitis group (RE group), non-erosive reflux disease group (NERD group) and Barrett’s esophagus group (BE group). HREM was performed to assess esophageal motility. Diverse questionnaires were conducted to evaluate severity of symptoms, quality of life, risk factors, degrees of anxiety and depression and so on. Results: a)Average resting pressures of the lower esophageal sphincter (LES), residual pressures of the LES and the esophageal distal contractile integral (DCI) score in P group were significantly lower than those in NP group (p<0.05). b)Average resting pressures of the upper esophageal sphincter (UES), residual pressures of the UES, lengths of the LES and the UES showed no difference between the two groups (p>0.05). c)Compared with NP group, the patients in P group had higher exposure to alcohol, coffee, sweets, overeating and stress (p<0.05). d)Anxiety and depression status of patients in P group were remarkably severer than those in NP group (p<0.05). e)The pain intensity in RE group and BE group was higher than NERD group (P<0.05), while there was no difference between RE group and BE group (P>0.05). Conclusions: Esophageal motility related anti-reflux barriers are much weaker in the RGERD patients with NCCP than those without NCCP, which mainly presents as the much lower average resting and residual pressures of the LES and DCI. Alcohol, coffee, sweets, overeating, stress, anxiety and depression are risk factors of RGERD-related NCCP. It’s suggested that the recovery of anti-reflux barriers and the avoidance of risk factors may be essential therapeutic strategies for improving the curative effect.

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