scholarly journals Accelerated Hypofractionated Radiotherapy in the Era of Concurrent Temozolomide Chemotherapy in Elderly Patients with Glioblastoma Multiforme

Cureus ◽  
2017 ◽  
Author(s):  
Liana Greer ◽  
Susan C. Pannullo ◽  
Andrew W Smith ◽  
Shoshana Taube ◽  
Menachem Z Yondorf ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Elderly Patients ◽  
Hypofractionated Radiotherapy ◽  
Temozolomide Chemotherapy ◽  
Accelerated Hypofractionated Radiotherapy

Hypofractionated radiotherapy with or without concurrent temozolomide in elderly patients with glioblastoma multiforme: a review of ten-year single institutional experience

2011 ◽  
Vol 107 (2) ◽  
pp. 395-405 ◽  
Author(s):  
Jeffrey Q. Cao ◽  
Barbara J. Fisher ◽  
Glenn S. Bauman ◽  
Joseph F. Megyesi ◽  
Christopher J. Watling ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Elderly Patients ◽  
Hypofractionated Radiotherapy ◽  
Institutional Experience

scholarly journals Advances in Immunotherapy for Glioblastoma Multiforme

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Boyuan Huang ◽  
Hongbo Zhang ◽  
Lijuan Gu ◽  
Bainxin Ye ◽  
Zhihong Jian ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Cancer Vaccines ◽  
Immune Checkpoint Blockade ◽  
First Line ◽  
Specific Cancer ◽  
Personalized Approach ◽  
Poor Outcomes ◽  
Temozolomide Chemotherapy ◽  
Primary Malignant Brain Tumor ◽  
First Line Treatment

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults. Patients with GBM have poor outcomes, even with the current gold-standard first-line treatment: maximal safe resection combined with radiotherapy and temozolomide chemotherapy. Accumulating evidence suggests that advances in antigen-specific cancer vaccines and immune checkpoint blockade in other advanced tumors may provide an appealing promise for immunotherapy in glioma. The future of therapy for GBM will likely incorporate a combinatorial, personalized approach, including current conventional treatments, active immunotherapeutics, plus agents targeting immunosuppressive checkpoints.

Survival Outcomes of Elderly Patients With Glioblastoma Multiforme in Their 75th Year or Older Treated With Adjuvant Therapy

2017 ◽  
Vol 98 (4) ◽  
pp. 802-810 ◽  
Author(s):  
Georgia Harris ◽  
Dasantha Jayamanne ◽  
Helen Wheeler ◽  
Cecelia Gzell ◽  
Marina Kastelan ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Adjuvant Therapy ◽  
Elderly Patients ◽  
Survival Outcomes

scholarly journals ACTR-47. COMBINED TREATMENT WITH HYPOFRACTIONATED RADIOTHERAPY AND TEMOZOLOMIDE BENEFITS OVER SINGLE TREATMENT IN ELDERLY PATIENTS WITH METHYLATED BUT NOT UNMETHYLATED MGMT GLIOBLASTOMA

2017 ◽  
Vol 19 (suppl_6) ◽  
pp. vi11-vi11
Author(s):  
Motoo Nagane ◽  
Yuki Yamagishi ◽  
Keiichi Kobayashi ◽  
Kuniaki Saito ◽  
Daisuke Shimada ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Combined Treatment ◽  
Hypofractionated Radiotherapy ◽  
Single Treatment
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