scholarly journals Urinary Tract Infection in Chronic Kidney Disease Population: A Clinical Observational Study

Cureus ◽  
2021 ◽  
Author(s):  
Mythri Shankar ◽  
Shashikala Narasimhappa ◽  
Madhura N.S.
Keyword(s):  
Chronic Kidney Disease ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Tract Infection ◽  
Observational Study ◽  
Chronic Kidney Disease Population

scholarly journals Urinary Tract Infection in Children: A Review of the Established Practice Guidelines

2020 ◽  
pp. 57-65
Author(s):  
Samuel Uwaezuoke ◽  
Adaeze Ayuk ◽  
Uzoamaka Muoneke
Keyword(s):  
Chronic Kidney Disease ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Tract Infection ◽  
Practice Guidelines ◽  
Renal Scarring ◽  
Clinical Excellence ◽  
Radiological Investigation ◽  
Delayed Treatment

Urinary tract infection (UTI) is a significant cause of morbidity in children. Delayed treatment is associated with complications that may result in chronic kidney disease and, subsequently, end-stage kidney disease. Over the years, clinical practice guidelines have advanced to ensure the best global practices in treating the infection and preventing its progression to chronic kidney disease. The established practice guidelines address five main questions: 1) which children should have their urine tested; 2) how the sample should be obtained; 3) which radiological tests are recommended after a diagnosis of UTI; 4) how the infection should be treated; 5) and how affected children should be followed up. There is a substantial overlap in the recommendations of the American Academy of Pediatrics (AAP) guidelines and the UK’s National Institute for Health and Clinical Excellence (NICE) guidelines. Subtle differences, however, exist between the two established guidelines. An evidence-based paradigm shift of some traditional concepts about UTI in children has contributed to the revision and update of these guidelines. Further research is needed to clarify the role of host and genetic factors in renal scarring, as well as the diagnostic criteria for UTI. This narrative review aims to discuss the current recommendations of these established practice guidelines with an emphasis on the diagnosis, radiological investigation, treatment, and follow-up of UTI in children.

scholarly journals Urinary tract infection in patients with chronic kidney disease

2014 ◽  
Vol 44 ◽  
pp. 145-149 ◽  
Author(s):  
Chih-Yen HSIAO ◽  
Hsing-Lin LIN ◽  
Yen-Ko LIN ◽  
Chao-Wen CHEN ◽  
Yuan-Chia CHENG ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Tract Infection

scholarly journals Urinary tract infection in patients with chronic kidney disease under conservative treatment

2022 ◽  
Vol 75 (3) ◽  
Author(s):  
Graciana Maria de Moraes Coutinho ◽  
Emanuela Cardoso da Silva ◽  
Cássia Regina Vancini Campanharo ◽  
Angélica Gonçalves Silva Belasco ◽  
Cassiane Dezoti da Fonseca ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Tract Infection ◽  
Conservative Treatment ◽  
University Hospital ◽  
Cross Sectional ◽  
Associated Risk Factors

ABSTRACT Objectives: to assess the prevalence and associated risk factors for urinary tract infection in patients with chronic kidney disease under conservative treatment and identify the microorganisms isolated in the urine of these patients and the staging of chronic kidney disease. Methods: a cross-sectional, analytical study carried out at the Conservative Treatment Outpatient Clinic of a university hospital in the city of São Paulo. Results: the prevalence of urinary tract infection is 22%. The risk factors Diabetes Mellitus, hypertension, heart disease, neoplasms and thyroid and autoimmune diseases stand out in the infected group (p < 0.001). Most of the microorganisms found in urine cultures (87.9%) were Gram-negative, being Escherichia coli (50.70%), followed by Klebsiella pneumoniae (23.1%) and Enterococcus spp. (9.7%). Conclusions: the findings of this investigation reveal the intrinsic association between risk factors and microorganisms for the development of urinary tract infection.

scholarly journals Pyuria, urinary tract infection and renal outcome in patients with chronic kidney disease stage 3–5

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
I-Ching Kuo ◽  
Jia-Jung Lee ◽  
Daw-Yang Hwang ◽  
Lee-Moay Lim ◽  
Hugo You-Hsien Lin ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Tract Infection ◽  
Hazard Ratio ◽  
Disease Stage ◽  
Renal Outcome ◽  
Renal Outcomes ◽  
Ckd Stage

Abstract Pyuria is common in chronic kidney disease (CKD), which could be due to either urinary tract infection (UTI) or renal parenchymal inflammation. Only little is known regarding the association of pyuria or UTI with renal outcomes. We investigated 3226 patients with stage 3–5 CKD. Pyuria was defined as ≥ 50 WBC per high-power field (hpf) and was correlated to old age, female, diabetes, hypoalbuminemia, lower eGFR, and higher inflammation status. In Cox regression, patients with more than one episode of pyuria in the first year (11.8%) had increased risks for end-stage renal disease (ESRD) [hazard ratio (95% CI): 1.90 (1.58–2.28); p < 0.001], rapid renal function progression [odds ratio (95% CI): 1.49 (1.13–1.95); p = 0.001], and all-cause mortality [hazard ratio: 1.63 (1.29–2.05); p < 0.001], compared to those without pyuria. In a subgroup analysis, the risk of pyuria for ESRD was modified by CKD stages. We investigated the effects of UTI (urinary symptoms and treated by antibiotics) and pyuria without UTI (urine WBC < 50 to ≥ 10/hpf without any episodes of ≥ 50 WBC/hpf or UTI), while both groups were associated with clinical outcomes. In conclusion, CKD stage 3–5 patients with frequent pyuria or UTI episodes have increased risks of renal outcomes.

Incidence of bacterial infections in chronic kidney disease patients admitted in nephrology unit of Kathmandu Medical College Teaching Hospital

2018 ◽  
Vol 7 (1) ◽  
pp. 26-29
Author(s):  
Laxman Adhikari
Keyword(s):  
Infectious Disease ◽  
Chronic Kidney Disease ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Tract Infection ◽  
Infectious Diseases ◽  
Bacterial Infections ◽  
College Teaching ◽  
Medical College

Background: Infectious diseases are one of the leading causes of morbidity and mortality in chronic kidney disease patients, second only to cardiovascular causes. As the incidence of chronic kidney disease is increasing, the number of deaths due to infectious disease is also increasing. Infectious disease includes infection, bacteremia and sepsis in chronic kidney disease patients.Objective: To assess the incidence of bacterial infections in chronic kidney disease patients.Methodology: A prospective cross-sectional study was done among all chronic kidney disease patients admitted over 6 months in Nephrology Unit of Department of Medicine, Kathmandu Medical College Teaching Hospital.Results: 58 patients were admitted with infectious diseases, out of which 6 patients (10.34%) died during treatment while 1 patient (1.78%) left against medical advice. Infection in patients undergoing dialysis (5D) was much more compared to stage 4 or 5chronic kidney disease patients (58.62% vs. 13.79% vs. 17.24% respectively). 19 patients (32.76%) had pneumonia, 16 patients (27.56%) had Urinary Tract Infection while 12 patients (20.70%) had sepsis. Although sepsis was less prevalent compared to pneumonia/ Urinary Tract Infection, deaths due to sepsis was very high.Conclusion: The incidence of bacterial infections in chronic kidney disease patients is still high despite all the improvements in infection control and dialysis practices, and still lots is left to be done to reduce the morbidity and mortality caused by infections in chronic kidney disease patients.

Renal medicine

2014 ◽  
Author(s):  
Murray Longmore ◽  
Ian B. Wilkinson ◽  
Andrew Baldwin ◽  
Elizabeth Wallin
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Urinary Tract Infection ◽  
Nephrotic Syndrome ◽  
Urinary Tract ◽  
Renal Replacement Therapy ◽  
Kidney Disease ◽  
Tract Infection ◽  
Mechanism Of Action ◽  
Kidney Injury

Introduction to nephrologyUrineUrinary tract infection (uti)Acute kidney injury (aki):DiagnosisManagementChronic kidney disease (ckd)ManagementRenal replacement therapy (rrt)Glomerulonephritis (gn)Nephrotic syndromeDiuretics and their mechanism of actionInterstitial nephritides and nephrotoxins...

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