scholarly journals Assessing the Outcome of Adult Kidney Transplantation from a Deceased Expanded Criteria Donor: A Descriptive Study

Cureus ◽  
2020 ◽  
Author(s):  
Mona Alshahrani ◽  
Mutlaq Alotaibi ◽  
Burhan Bhutto
Keyword(s):  
Kidney Transplantation ◽  
Descriptive Study ◽  
Expanded Criteria Donor ◽  
Adult Kidney ◽  
Expanded Criteria

scholarly journals Does kidney transplantation with a standard or expanded criteria donor improve patient survival? Results from a Belgian cohort

2021 ◽  
Vol 36 (5) ◽  
pp. 918-926
Author(s):  
Rachel Hellemans ◽  
Anneke Kramer ◽  
Johan De Meester ◽  
Frederic Collart ◽  
Dirk Kuypers ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Survival Benefit ◽  
Age Groups ◽  
Deceased Donor ◽  
Risk Levels ◽  
Improve Patient Survival ◽  
Expanded Criteria Donor ◽  
Expanded Criteria ◽  
Deceased Donor Kidney Transplant ◽  
Dialysis Outcomes

Abstract Background Changes in recipient and donor factors have reopened the question of survival benefits of kidney transplantation versus dialysis. Methods We analysed survival among 3808 adult Belgian patients waitlisted for a first deceased donor kidney transplant from 2000 to 2012. The primary outcome was mortality during the median waiting time plus 3 years of follow-up after transplantation or with continued dialysis. Outcomes were analysed separately for standard criteria donor (SCD) and expanded criteria donor (ECD) kidney transplants. We adjusted survival analyses for recipient age (20–44, 45–64 and ≥65 years), sex and diabetes as the primary renal disease. Results Among patients ≥65 years of age, only SCD transplantation provided a significant survival benefit compared with dialysis, with a mortality of 16.3% [95% confidence interval (CI) 13.2–19.9] with SCD transplantation, 20.5% (95% CI 16.1–24.6) with ECD transplantation and 24.6% (95% CI 19.4–29.5) with continued dialysis. Relative mortality risk was increased in the first months after transplantation compared with dialysis, with equivalent risk levels reached earlier with SCD than ECD transplantation in all age groups. Conclusions The results of this study suggest that older patients might gain a survival benefit with SCD transplantation versus dialysis, but any survival benefit with ECD transplantation versus dialysis may be small.

Acceptable Outcome After Kidney Transplantation Using “Expanded Criteria Donor” Grafts

2010 ◽  
Vol 89 (1) ◽  
pp. 88-96 ◽  
Author(s):  
Sheila M. Fraser ◽  
Rajaganeshan Rajasundaram ◽  
Amer Aldouri ◽  
Shahid Farid ◽  
Gareth Morris-Stiff ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Expanded Criteria Donor ◽  
Expanded Criteria ◽  
Acceptable Outcome

Effects of Cold Ichemic Time on Allograft Survival in Kidney Transplantation From Expanded Criteria Donor

2017 ◽  
Vol 101 ◽  
pp. S51 ◽  
Author(s):  
Kajohnsak Noppakun ◽  
Adisorn Lumpaopong ◽  
Thanom Supaporn ◽  
Vasant Sumethkul
Keyword(s):  
Kidney Transplantation ◽  
Allograft Survival ◽  
Expanded Criteria Donor ◽  
Expanded Criteria

scholarly journals Machine perfusion versus static cold storage in expanded criteria donor kidney transplantation: 3-year follow-up data

2013 ◽  
Vol 26 (6) ◽  
pp. E52-E53 ◽  
Author(s):  
Anja Gallinat ◽  
Cyril Moers ◽  
Jacqueline M. Smits ◽  
Agita Strelniece ◽  
Jacques Pirenne ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Cold Storage ◽  
Machine Perfusion ◽  
Donor Kidney ◽  
Expanded Criteria Donor ◽  
Expanded Criteria ◽  
Donor Kidney Transplantation

Kidney transplantation after rescue allocation—meticulous selection yields the chance for excellent outcome

2020 ◽  
Author(s):  
Volker Assfalg ◽  
Svea Misselwitz ◽  
Lutz Renders ◽  
Norbert Hüser ◽  
Alexander Novotny ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Patient Survival ◽  
Graft Function ◽  
Outcome Data ◽  
Organ Donors ◽  
Excellent Outcome ◽  
Expanded Criteria Donor ◽  
History Of ◽  
Criteria Catalogue ◽  
Expanded Criteria

Abstract Background The small number of organ donors forces transplant centres to consider potentially suboptimal kidneys for transplantation. Eurotransplant established an algorithm for rescue allocation (RA) of kidneys repeatedly declined or not allocated within 5 h after procurement. Data on the outcomes and benefits of RA are scarce to date. Methods We conducted a retrospective 8-year analysis of transplant outcomes of RA offers based on our in-house criteria catalogue for acceptance and decline of organs and potential recipients. Results RA donors and recipients were both older compared with standard allocation (SA). RA donors more frequently had a history of hypertension, diabetes or fulfilled expanded criteria donor key parameters. RA recipients had poorer human leucocyte antigen (HLA) matches and longer cold ischaemia times (CITs). However, waiting time was shorter and delayed graft function, primary non-function and biopsy-proven rejections were comparable to SA. Five-year graft and patient survival after RA were similar to SA. In multivariate models accounting for confounding factors, graft survival and mortality after RA and SA were comparable as well. Conclusions Facing relevant comorbidities and rapid deterioration with the risk of being removed from the waiting list, kidney transplantation after RA was identified to allow for earlier transplantation with excellent outcome. Data from this survey propose not to reject categorically organs from multimorbid donors with older age and a history of hypertension or diabetes to aim for the best possible HLA matching and to carefully calculate overall expected CIT.

Sign in / Sign up

Export Citation Format

Share Document