scholarly journals Refractory Kawasaki Disease Presenting With Erythema at Bacille Calmette-Guérin Inoculation Site: A Paediatric Case Report

Cureus ◽  
2020 ◽  
Author(s):  
Vijayakumary Thadchanamoorthy ◽  
Kavinda Dayasiri
Keyword(s):  
Case Report ◽  
Kawasaki Disease ◽  
Bacille Calmette Guerin ◽  
Inoculation Site ◽  
Paediatric Case

Typical Kawasaki disease with atypical pneumonia: a paediatric case report

2020 ◽  
pp. 1-2
Author(s):  
MC Maggio ◽  
R Cimaz ◽  
MC Failla ◽  
P Dones ◽  
G Corsello
Keyword(s):  
Case Report ◽  
Kawasaki Disease ◽  
Atypical Pneumonia ◽  
Paediatric Case

scholarly journals Diagnosis of Incomplete Kawasaki Disease in Infants Based on an Inflammation at the Bacille Calmette-Guérin Inoculation Site

2012 ◽  
Vol 42 (12) ◽  
pp. 823 ◽  
Author(s):  
Ji Hye Seo ◽  
Jeong Jin Yu ◽  
Hong Ki Ko ◽  
Hyung Soon Choi ◽  
Young-Hwue Kim ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Incomplete Kawasaki Disease ◽  
Bacille Calmette Guerin ◽  
Inoculation Site

Kawasaki Disease Patients With Redness or Crust Formation at the Bacille Calmette-Guérin Inoculation Site

2010 ◽  
Vol 29 (5) ◽  
pp. 430-433 ◽  
Author(s):  
Ritei Uehara ◽  
Hiroshi Igarashi ◽  
Mayumi Yashiro ◽  
Yosikazu Nakamura ◽  
Hiroshi Yanagawa
Keyword(s):  
Kawasaki Disease ◽  
Crust Formation ◽  
Bacille Calmette Guerin ◽  
Inoculation Site

Abstract 200: Afebrile Kawasaki Disease Beyond Diagnostic Guideline Evolving Coronary Artery Complication

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Sun Hwa Lee ◽  
Na Yeon Kim
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Diagnostic Algorithm ◽  
Clinical Feature ◽  
Z Score ◽  
Bacille Calmette Guerin ◽  
Inoculation Site ◽  
Diagnostic Guideline ◽  
Specific Finding

Kawasaki disease (KD) is diagnosed with clinical features. Presence of at least five days of fever is major criteria. Herein we report a 7 month -old boy diagnosed as afebrile kawasaki disease who initially presented with inflammation at the Bacille Calmette-Guerin (BCG) inoculation site (BCGitis) with multiple erythematous papular rash, followed by desquamation of finger tips at 11 day of illness. Laboratory test showed elevated ALT (110 U/L) and otherwise showed no specific finding. Clinical feature disappeared spontaneously except BCGitis. The patient did not fulfill the diagnostic criteria but progressive coronary arterial dilatation was noticed. Left coronary artery (LMCA) was dilated from Z-score 1.6 (3 day of illness) to 2.8 (11 day of illness). After treated with intravenous immunoglobulin (2g/kg), BCGitis disappeared and follow up echocardiogram showed normalized LMCA lesion (Z-score 1.0 at 17 day of illness). BCGitis was considered to be pathognomonic feature of this patient. Diagnostic algorithm and guidelines are useful tool for the incomplete KD patients but clinicians should also be cautious for the patient with BCGitis even they are excluded by diagnostic guideline.

Bacille Calmette-Guérin inoculation site changes and cardiac complications in patients with Kawasaki disease

2020 ◽  
pp. archdischild-2020-319543
Author(s):  
Haruki Takikawa ◽  
Ryusuke Ae ◽  
Yuri Matsubara ◽  
Daisuke Matsubara ◽  
Nobuko Makino ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Ivig Treatment ◽  
Cardiac Complications ◽  
Independent Factor ◽  
Bacille Calmette Guerin ◽  
Treatment And Prevention ◽  
Inoculation Site ◽  
Paediatric Department ◽  
Using Data ◽  
Adjusted Model

ObjectiveTo investigate whether redness and crusting at the bacille Calmette-Guérin inoculation site (BCGitis), identified during acute illness owing to Kawasaki disease (KD), is an independent risk factor for development of cardiac complications.DesignRetrospective cohort study using data from the nationwide KD survey in Japan.SettingSurvey respondents included hospitals specialising in paediatrics and hospitals with ≥100 beds and a paediatric department throughout Japan.PatientsWe included 17 181 patients with KD across Japan during 2005–2006.Main outcome measuresBCGitis and cardiac complications resulting from KD.ResultsBCGitis was identified in 7549 (44%) patients with KD. Compared with patients without BCGitis, those with BCGitis were younger, more likely to be male, less likely to have recurrent status and visited a hospital and underwent initial intravenous immunoglobulin (IVIG) treatment earlier after KD onset. In the unadjusted model, patients with BCGitis were significantly less likely to have cardiac complications (crude OR 0.81, 95% CI 0.71 to 0.92). However, after including treatment factors (days of illness at initial IVIG and treatment responsiveness) in the adjusted model, the association was no longer significant (adjusted OR 0.89, 95% CI 0.77 to 1.03), indicating that BCGitis was not an independent factor associated with cardiac complication and might be confounded by treatment factors.ConclusionsBCGitis was identified in comparatively early illness stages of KD. Our findings indicated that BCGitis was not an independent factor associated with developing cardiac complications but was confounded by prompt initial IVIG administration, which might result in successful treatment and prevention of cardiac complications.

scholarly journals Analysis of factors associated with development of Bacille Calmette–Guérin inoculation site change in patients with Kawasaki disease

2018 ◽  
Vol 46 (4) ◽  
pp. 1640-1648 ◽  
Author(s):  
Tooru Araki ◽  
Aya Kodera ◽  
Kunimi Kitada ◽  
Michimasa Fujiwara ◽  
Michiko Muraoka ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Clinical Severity ◽  
Bacille Calmette Guerin ◽  
Bcg Vaccination ◽  
Factors Associated ◽  
Patient Demographics ◽  
Site Change ◽  
Inoculation Site ◽  
Group A ◽  
Echocardiographic Findings

Objective The present study was performed to identify factors associated with a Bacille Calmette–Guérin (BCG) inoculation site change in patients with Kawasaki disease (KD). Methods Among patients who had received BCG vaccination and treatment for KD at our hospital from 2005 through 2016, 177 patients born in 2005 through 2016 were enrolled. The patients were divided into those with (n = 83, change group) and without (n = 94, no-change group) a BCG site change, and the patient demographics, clinical severity, blood examination results, and echocardiographic findings were compared between the two groups. Results The change group was younger at onset and had a shorter interval from vaccination to onset. A BCG site change was observed in patients who developed the onset of KD symptoms from 31 to 806 days after BCG vaccination. Multivariate analysis showed that the interval from vaccination was closely and positively associated with the BCG site change (hazard ratio = 0.995, 95% confidence interval = 0.993–0.997). Conclusion A BCG site change in patients with KD is most closely associated with the interval from BCG vaccination to onset.

scholarly journals 4CPS-263 Case report of Kawasaki disease and SARS-CoV-2 infection in a paediatric hospital

2021 ◽  
Author(s):  
E Murrja ◽  
A Simonini ◽  
GB Ortenzi ◽  
R Sentinelli ◽  
AMF Garzone ◽  
...  
Keyword(s):  
Case Report ◽  
Kawasaki Disease ◽  
Paediatric Hospital
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