scholarly journals Pro-Atherogenic Inflammatory Mediators in Inflammatory Bowel Disease Patients Increase the Risk of Thrombosis, Coronary Artery Disease, and Myocardial Infarction: A Scientific Dilemma

Cureus ◽  
2020 ◽  
Author(s):  
Kaushik Kondubhatla ◽  
Ayush Kaushal ◽  
Ali Daoud ◽  
Hassan Shabbir ◽  
Jihan A Mostafa
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Inflammatory Bowel Disease ◽  
Coronary Artery ◽  
Inflammatory Mediators ◽  
Bowel Disease ◽  
Inflammatory Bowel ◽  
Artery Disease

Inflammatory Bowel Disease: A Potential Risk Factor for Coronary Artery Disease

Angiology ◽  
2017 ◽  
Vol 68 (10) ◽  
pp. 845-849 ◽  
Author(s):  
Grigorios Tsigkas ◽  
Periklis Davlouros ◽  
Stefanos Despotopoulos ◽  
Stelios F. Assimakopoulos ◽  
Georgios Theocharis ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Inflammatory Bowel Disease ◽  
Coronary Artery ◽  
Family History ◽  
Bowel Disease ◽  
Antiphospholipid Antibody ◽  
Coronary Syndrome ◽  
History Of ◽  
Inflammatory Bowel ◽  
Artery Disease

Patients with inflammatory bowel disease (IBD) have a higher incidence of coronary artery disease (CAD) compared with the general population. Left main coronary artery (LMCA) thrombosis constitutes a very rare but catastrophic manifestation of acute coronary syndrome. Case reports describing young patients with IBD and LMCA thrombosis are scarce. Most importantly, patients with a positive family history of thrombotic events and those with significant genetic or acquired risk factors such as the antiphospholipid antibody syndrome, advanced age, immobilization, pregnancy, oral contraceptive use, obesity, diabetes, and cigarette smoking may have a higher risk of thrombosis among those with active IBD. We describe a 28-year-old man who was admitted for coronary angiography (CA) due to ST-segment elevation myocardial infarction. He had a recent exacerbation of ulcerative colitis. The patient was a smoker without a family history of CAD. Proximal total occlusion of the left anterior descending (LAD) artery and left circumflex (LCX) artery with massive thrombus was shown on CA, whereas a normal dominant right coronary artery delivered collaterals to the LAD artery.

Inflammatory bowel disease and coronary artery disease

2009 ◽  
Vol 28 (1) ◽  
pp. 28-30 ◽  
Author(s):  
Raja Shekhar R. Sappati Biyyani ◽  
Nabil M. Fahmy ◽  
Elizabeth Baum ◽  
Karl M. Nelson ◽  
James F. King
Keyword(s):  
Coronary Artery Disease ◽  
Inflammatory Bowel Disease ◽  
Coronary Artery ◽  
Bowel Disease ◽  
Inflammatory Bowel ◽  
Artery Disease
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