scholarly journals The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience

Cureus ◽  
2020 ◽  
Author(s):  
Muhammad Adrish ◽  
Sridhar Chilimuri ◽  
Haozhe Sun ◽  
Nikhitha Mantri ◽  
Alla Yugay ◽  
...  
Keyword(s):  
Ethnic Minority ◽  
Patient Population ◽  
Minority Patient ◽  
Renin Angiotensin Aldosterone System ◽  
Renin Angiotensin ◽  
Ethnic Minority Patient

Racial and ethnic minority patient participation in N-of-1 trials: perspectives of healthcare providers and patients

2021 ◽  
Author(s):  
Lyndonna Marrast ◽  
Joseph Conigliaro ◽  
Camille Chan ◽  
Eun Ji Kim ◽  
Joan Duer-Hefele ◽  
...  
Keyword(s):  
Primary Care ◽  
Ethnic Minority ◽  
Healthcare Providers ◽  
Design Feature ◽  
Lifestyle Changes ◽  
Trial Recruitment ◽  
Minority Patient ◽  
Ethnic Minority Patient ◽  
The Usa ◽  
Racial And Ethnic Minority

Aim: Patients from racial and ethnic minority backgrounds in the USA have historically been under-represented in research trials. Understanding their viewpoints regarding participation in N-of-1 trials is imperative as we design and implement these studies. Materials & methods: We conducted six focus groups of racial and ethnic minority patients (n = 25) and providers (n = 9). We used content analysis to identify themes. Results: Our results noted the importance of considering family members in N-of-1 trial recruitment and participation, patients’ desire for education as a design feature, for ‘lifestyle’ changes as a treatment option and for use of nonevidence-based treatments in the design of future N-of-1 trials. Conclusion: Personalized trials have the potential to change the way we deliver primary care and improve disparities for minorities.

EFFECTS OF PROGESTERONE AND OF FOUR SYNTHETIC GESTAGENS ON THE RENIN-ANGIOTENSIN-ALDOSTERONE-SYSTEM IN MAN.

1974 ◽  
Vol 77 (1_Suppl) ◽  
pp. S55
Author(s):  
W. Oelkers ◽  
M. Schöneshöfer ◽  
H. Blümel ◽  
H. Kutschke ◽  
H. Kreiser ◽  
...  
Keyword(s):  
Renin Angiotensin Aldosterone System ◽  
Renin Angiotensin

NATRIURETIC PEPTIDES LEVEL AND THE STATUS OF THE RENIN – ANGIOTENSIN-ALDOSTERONE SYSTEM IN CHRONIC KIDNEY DISEASE IN PATIENTS WITH CONGENITAL MALFORMATIONS OF THE URINARY SYSTEM

2018 ◽  
Vol 22 (5) ◽  
pp. 45-50
Author(s):  
A. M. Mambetova ◽  
A. M. Inarokova ◽  
N. N. Shabalova ◽  
D. V. Bizheva ◽  
A. T. Mahiyeva
Keyword(s):  
Congenital Malformations ◽  
Control Group ◽  
Healthy Children ◽  
Urinary System ◽  
Renin Angiotensin Aldosterone System ◽  
Natriuretic Hormone ◽  
Renin Angiotensin ◽  
Group I ◽  
The Status ◽  
Sick Children

THE AIM. To determine the concentration of natriuretic peptide in the blood serum in children with congenital malformations of the urinary system (CM US) and to compare with the activity of renin-angiotensin-aldosterone system (RAAS).MATERIALS AND METHODS.119 patients with CM US aged 3 to 18 years were examined. A control group of 10 clinically healthy children. 3 groups were assigned: group I – 55 children with  congenital vesicoureteral reflux, and group II – 34 children with  congenital hydronephrosis and ureterohydronephrosis, III group – 30 children with other forms of dysembryogenesis of the US. Following indicators were identified by ELISA in the blood: renin, aldosterone,  N – terminal propeptide natriuretic hormone (NT-рroВNР). RESULTS.NT-рroВNР, renin and aldosterone hyperproduction were diagnosed in 59,6%, 69,7%, 54.6 % of sick children relatively. Concentrations were higher in all variants of  malformations in comparison with the control group. Significant  differences were revealed in obstructive species, where arterial  hypertension (AH) was diagnosed more often. Patients with AH  recorded significantly higher concentrations of NT-proВNР and renin.CONCLUSION.The key point in pathological processes developmentand progression in the cardiovascular system and kidneys is the  activation of RAAS. The system of natriuretic factors is important in maintaining the compensated state of patients due to the blockade of RAAS.

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