scholarly journals Comparison of long-term kidney functions after radical nephrectomy and simple nephrectomy

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6701
Author(s):  
Erkan Olcucuoglu ◽  
Senol Tonyali ◽  
Sedat Tastemur ◽  
Yusuf Kasap ◽  
Mehmet Emin Sirin ◽  
...  
Keyword(s):  
Renal Function ◽  
Radical Nephrectomy ◽  
Group Versus ◽  
Compensation Mechanisms ◽  
Nephron Loss ◽  
Short And Long Term ◽  
Mdrd Formula ◽  
Group 2 ◽  
Kidney Functions

Objective To determine if there is a difference in proceeding to CKD between patients who had undergone radical nephrectomy (RN) and simple nephrectomy (SN) for different indications by comparing the short- and long-term renal function. Materials and Methods We retrospectively analyzed the records of all patients who underwent nephrectomy (either for malign or benign indications) in our clinic between January 2007 and September 2017. The patients were divided into 2 groups according the type of surgery: 1) Radical nephrectomy Group, 2) Simple Nephrectomy Group. Renal function was evaluated with Glomerular Filtration Rate (GFR) calculated using the MDRD formula. Results A total of 276 patients were included in the study. There were 202 patients in RN Group and 74 patients in SN Group. The mean age of the patients in RN Group and SN Group were age 59,2 ± 11,5 and 49,9 ± 15,1 years, respectively (p = 0.001). GFR levels of patients in RN Group versus SN Group were as follows: Preoperative period: 84.9 vs. 81 mL/min/1.73 m2; postoperative 1st day: 60.5 vs. 84.4 mL/min/1.73 m2, postoperative 1st month 58.9 vs. 76 mL/min/1.73 m2, postoperative 1st year: 59.5 vs. 74.1 mL/min/1.73 m2; at last control 60.3 and 76.1 mL/min/1.73 m2. While preoperative GFR was found to be similar in two groups (p = 0.26), postoperative GFR values were found to be significantly lower in Group RN (p < 0.001). In comparison of the decrease in GFR in two groups at last follow-up, significantly higher decrease was observed in RN Group, 29% vs. 6%, (p < 0.05). Conclusion The decrease in GFR exists more common and intensive after RN compared to SN. In long-term, compensation mechanisms that develop after sudden nephron loss like radical nephrectomy deteriorates kidney function more than gradual nephron loss as in benign etiologies which indicates simple nephrectomy.

scholarly journals Renal function and anemia in relation to short- and long-term prognosis of patients with acute heart failure in the period 1985-2008: A clinical cohort study

PLoS ONE ◽  
2018 ◽  
Vol 13 (8) ◽  
pp. e0201714 ◽  
Author(s):  
Jan C. van den Berge ◽  
Alina A. Constantinescu ◽  
Ron T. van Domburg ◽  
Milos Brankovic ◽  
Jaap W. Deckers ◽  
...  
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Cohort Study ◽  
Acute Heart Failure ◽  
Clinical Cohort ◽  
Short And Long Term ◽  
Long Term Prognosis

Group versus Individual Liability: Short and Long Term Evidence from Philippine Microcredit Lending Groups

2016 ◽  
Author(s):  
Dean Karlan ◽  
Sneha Stephen ◽  
Xavier Gine ◽  
Keesler Welch ◽  
Jacob Geray
Keyword(s):  
Group Versus ◽  
Short And Long Term

Group versus Individual Liability: Short and Long Term Evidence from Philippine Microcredit Lending Groups

2016 ◽  
Author(s):  
Dean Karlan ◽  
Sneha Stephen ◽  
Xavier Gine ◽  
Keesler Welch ◽  
Jacob Geray
Keyword(s):  
Group Versus ◽  
Short And Long Term

scholarly journals Long-Term Renal Function Recovery following Radical Nephrectomy for Kidney Cancer: Results from a Multicenter Confirmatory Study

2018 ◽  
Vol 199 (4) ◽  
pp. 921-926 ◽  
Author(s):  
Emily C. Zabor ◽  
Helena Furberg ◽  
Byron Lee ◽  
Steven Campbell ◽  
Brian R. Lane ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Cancer ◽  
Radical Nephrectomy ◽  
Renal Function Recovery ◽  
Function Recovery

scholarly journals Tissue Kidney Injury Molecule-1 Expression in the Prediction of Renal Function for Several Years after Kidney Biopsy

2013 ◽  
Vol 35 ◽  
pp. 567-572 ◽  
Author(s):  
Sanja Simic Ogrizovic ◽  
Suzana Bojic ◽  
Gordana Basta-Jovanovic ◽  
Sanja Radojevic ◽  
Jelena Pavlovic ◽  
...  
Keyword(s):  
Renal Function ◽  
Retrospective Study ◽  
Kidney Function ◽  
Kidney Biopsy ◽  
Kidney Diseases ◽  
Kidney Injury ◽  
Mdrd Formula ◽  
Positive Correlations ◽  
Kidney Injury Molecule 1 ◽  
Kidney Functions

Objectives. Retrospective study was designed to examine the importance of tissue kidney injury molecule-1 (KIM-1) expression in predicting kidney function in sixty patients (27 males) aged 34.15 ± 12.23 years with different kidney diseases over three years after kidney biopsy.Materials and Methods. Tissue KIM-1 expression was determined immunohistochemically and KIM-1 staining was scored semiquantitatively, as well as tubulointerstitialis (TIN), inflammation, atrophy, and fibrosis. Kidney function (MDRD formula) and proteinuria/day were evaluated at the time of biopsy (GFR0) and 6, 12, 24, and 36 months later.Results. Significantly positive correlations between tissue KIM-1 expression and age (r=0.313), TIN inflammation (r=0.456), fibrosis (r=0.317), and proteinuria at 6 months (r=0.394) as well as negative correlations with GFR0 (r=−0.572), GFR6 (r=−0.442), GFR24 (r=−0.398), and GFR36 (r=−0.412) were found. Meanwhile, TIN inflammation was the best predictor of all measured kidney functions during three years, while tissue KIM-1 expression (P=0.016) was a predictor only at 6 months after biopsy.Conclusion. Tissue KIM-1 expression significantly predicts kidney function solely at 6 months after biopsy, when the effects of immune and nonimmune treatments are the strongest.

scholarly journals PC038 The Impact of Contrast Media Volume Used During Endovascular Aneurysm Repair on Short- and Long-Term Renal Function

2017 ◽  
Vol 65 (6) ◽  
pp. 149S
Author(s):  
Jennifer C. Grom ◽  
Rami O. Tadros ◽  
Melissa Baldwin ◽  
Martin Kang ◽  
Daniel K. Han ◽  
...  
Keyword(s):  
Renal Function ◽  
Contrast Media ◽  
Endovascular Aneurysm Repair ◽  
Short And Long Term ◽  
Aneurysm Repair ◽  
The Impact ◽  
Media Volume

scholarly journals MP52-07 SHORT AND LONG TERM IMPACT OF TOBACCO SMOKING ON DONOR RENAL FUNCTION FOLLOWING LIVE KIDNEY DONATION

2020 ◽  
Vol 203 ◽  
pp. e774
Author(s):  
Christopher Kauffman-Ortega* ◽  
Adrian M. Garza-Gangemi ◽  
Mariano Oropeza-Aguilar ◽  
Bernardo Gabilondo-Pliego ◽  
Francisco T. Rodriguez-Covarrubias
Keyword(s):  
Renal Function ◽  
Tobacco Smoking ◽  
Kidney Donation ◽  
Live Kidney Donation ◽  
Short And Long Term ◽  
Long Term Impact

scholarly journals Post nephrectomy renal function: Donor nephrectomy versus radical nephrectomy

2021 ◽  
pp. 102-102
Author(s):  
Jelena Tadic ◽  
Nemanja Rancic ◽  
Katarina Obrencevic ◽  
Milorad Radojevic ◽  
Predrag Maric ◽  
...  
Keyword(s):  
Renal Function ◽  
Radical Nephrectomy ◽  
Clinical Stage ◽  
Donor Nephrectomy ◽  
Control Group ◽  
Retrospective Case ◽  
Kidney Tumors ◽  
Cell Renal Cell Carcinoma ◽  
Adaptive Mechanisms ◽  
Group 2

Background/Aim. Monitoring the renal function following donor or radical nephrectomy due to kidney tumors is considered to be essential. The aim of this study was to compare pre-operative and post-operative renal function in patients who underwent donor nephrectomy in relation to patients who underwent radical nephrectomy due to renal malignancy. Methods. A retrospective case-control study was performed, which included 199 patients divided into two groups: Group 1 (105 patients) were patients who underwent donor nephrectomy due to living related/unrelated kidney transplantation, while group 2 (94 patients) was a control group and included patients who underwent radical nephrectomy due to clear cell renal cell carcinoma in the T1bNoM0 clinical stage, where this surgical procedure was the final form of treatment. Results. Pre-operative eGFR EPI in the donor group was 94.95 ml/min/1.73m2, while in the radical nephrectomy patient group it was 71.00 ml/min/1.73m2. Patients who underwent radical nephrectomy tended to have GFR below 60 ml/min/1.73m2 after ten years of follow-up compared with patients who underwent donor nephrectomy. In the donor nephrectomy group, the average GFR was 80.40 ml/min/1.73m2 and in the radical nephrectomy group it was 56.00 ml/min/1.73m2. A higher incidence of diabetes and hypertension was also observed in the donor nephrectomy group of patients compared to the radical nephrectomy group (HTA: 44.3% vs. 21.3%; diabetes: 22.6% vs. 9.6%, respectively). Conclusion. Comparative monitoring of these two groups showed that in both groups the recovery of renal reserve was achieved one year after nephrectomy, due to the known adaptive mechanisms. Regardless of the fact that with live transplantation in a kidney donor, we reduce the initial renal reserve (nephrectomy, permanent loss of renal mass), due to the adaptive mechanisms, kidney donors recover the kidney function within the first year after surgery.

Group versus Individual Liability: Short and Long Term Evidence from Philippine Microcredit Lending Groups

2016 ◽  
Author(s):  
Dean Karlan ◽  
Sneha Stephen ◽  
Xavier Gine ◽  
Keesler Welch ◽  
Jacob Geray
Keyword(s):  
Group Versus ◽  
Short And Long Term
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