scholarly journals Optimizing the trainable B-COSFIRE filter for retinal blood vessel segmentation

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5855 ◽  
Author(s):  
Sufian A. Badawi ◽  
Muhammad Moazam Fraz
Keyword(s):  
Blood Vessel ◽  
Optimization Procedure ◽  
Vessel Segmentation ◽  
Automated System ◽  
Suggested Approach ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels ◽  
Analysis Technique ◽  
Public Datasets ◽  
Performance Results

Segmentation of the retinal blood vessels using filtering techniques is a widely used step in the development of an automated system for diagnostic retinal image analysis. This paper optimized the blood vessel segmentation, by extending the trainable B-COSFIRE filter via identification of more optimal parameters. The filter parameters are introduced using an optimization procedure to three public datasets (STARE, DRIVE, and CHASE-DB1). The suggested approach considers analyzing thresholding parameters selection followed by application of background artifacts removal techniques. The approach results are better than the other state of the art methods used for vessel segmentation. ANOVA analysis technique is also used to identify the most significant parameters that are impacting the performance results (p-value ¡ 0.05). The proposed enhancement has improved the vessel segmentation accuracy in DRIVE, STARE and CHASE-DB1 to 95.47, 95.30 and 95.30, respectively.

Retinal Blood Vessel Segmentation Using Ensemble of Single Oriented Mask Filters

2017 ◽  
Vol 7 (3) ◽  
pp. 1414
Author(s):  
Fauziah Kasmin ◽  
Azizi Abdullah ◽  
Anton Satria Prabuwono
Keyword(s):  
Blood Vessel ◽  
Vessel Segmentation ◽  
Support Vector ◽  
Retinal Images ◽  
Blood Vessel Segmentation ◽  
Training Images ◽  
Retinal Blood Vessels ◽  
Average Accuracy ◽  
Long Time ◽  
Automated Screening

This paper describes a method on segmentation of blood vessel in retinal images using supervised approach. Blood vessel segmentation in retinal images can be used for analyses in diabetic retinopathy automated screening. It is a very exhausting job and took a very long time to segment retinal blood vessels manually. Moreover these tasks also requires training and skills. The strategy involves the applications of Support Vector Machine to classify each pixel whether it belongs to a vessel or not. Single mask filters which consist of intensity values of normalized green channel have been generated according to the direction of angles. These single oriented mask filters contain the vectors of the neighbourhood of each pixel. Five images randomly selected from DRIVE database are used to train the classifier. Every single oriented mask filters are ranked according to the average accuracy of training images and their weights are assigned based on this rank.  Ensemble approaches that are Addition With Weight and Product With Weight have been used to combine all these single mask filters. In order to test the proposed approach, two standard databases, DRIVE and STARE have been used. The results of the proposed method clearly show improvement compared to other single oriented mask filters.

scholarly journals Retinal blood vessel segmentation using a deep learning method based on modified U-NET model

2021 ◽  
Author(s):  
Sanjeewani NA ◽  
arun kumar yadav ◽  
Mohd Akbar ◽  
mohit kumar ◽  
Divakar Yadav
Keyword(s):  
Deep Learning ◽  
Blood Vessel ◽  
Blood Vessels ◽  
Automatic Segmentation ◽  
Vessel Segmentation ◽  
Great Success ◽  
Retinal Blood Vessel ◽  
Data Set ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels

<div>Automatic retinal blood vessel segmentation is very crucial to ophthalmology. It plays a vital role in the early detection of several retinal diseases such as Diabetic Retinopathy, hypertension, etc. In recent times, deep learning based methods have attained great success in automatic segmentation of retinal blood vessels from images. In this paper, a U-NET based architecture is proposed to segment the retinal blood vessels from fundus images of the eye. Furthermore, 3 pre-processing algorithms are also proposed to enhance the performance of the system. The proposed architecture has provided significant results. On the basis of experimental evaluation on the publicly available DRIVE data set, it has been observed that the average accuracy (Acc) is .9577, sensitivity (Se) is .7436, specificity (Sp) is .9838 and F1-score is .7931. The proposed system outperforms all recent state of art approaches mentioned in the literature.</div>

A New Deeply Convolutional Neural Network Architecture for Retinal Blood Vessel Segmentation

2020 ◽  
pp. 2157001
Author(s):  
Mali Mohammedhasan ◽  
Harun Uğuz
Keyword(s):  
Neural Network ◽  
Blood Vessel ◽  
Convolutional Neural Network ◽  
Blood Vessels ◽  
Network Architecture ◽  
Vessel Segmentation ◽  
Retinal Blood Vessel ◽  
Low Level ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels

This paper proposes an incoming Deep Convolutional Neural Network (CNN) architecture for segmenting retinal blood vessels automatically from fundus images. Automatic segmentation performs a substantial role in computer-aided diagnosis of retinal diseases; it is of considerable significance as eye diseases as well as some other systemic diseases give rise to perceivable pathologic changes. Retinal blood vessel segmentation is challenging because of the excessive changes in the morphology of the vessels on a noisy background. Previous deep learning-based supervised methods suffer from the insufficient use of low-level features which is advantageous in semantic segmentation tasks. The proposed architecture makes use of both high-level features and low-level features to segment retinal blood vessels. The major contribution of the proposed architecture concentrates on two important factors; the first in its supplying of extremely modularized network architecture of aggregated residual connections which enable us to copy the learned layers from the shallower model and developing additional layers to identity mapping. The second is to improve the utilization of computing resources within the network. This is achieved through a skillfully crafted design that allows for increased depth and width of the network while maintaining the stability of its computational budget. Experimental results show the effectiveness of using aggregated residual connections in segmenting retinal vessels more accurately and clearly. Compared to the best existing methods, the proposed method outperformed other existing methods in different measures, comprised less false positives at fine vessels, and caressed more clear lines with sufficient details like the human annotator.

scholarly journals An Effective Retinal Blood Vessel Segmentation by Using Automatic Random Walks Based on Centerline Extraction

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Jianqing Gao ◽  
Guannan Chen ◽  
Wenru Lin
Keyword(s):  
Random Walk ◽  
Blood Vessel ◽  
Blood Vessels ◽  
Morphological Characteristics ◽  
Maximum Intensity Projection ◽  
Vessel Segmentation ◽  
Retinal Blood Vessel ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels ◽  
Structured Analysis

The retinal blood vessel analysis has been widely used in the diagnoses of diseases by ophthalmologists. According to the complex morphological characteristics of the blood vessels in normal and abnormal images, an automatic method by using the random walk algorithms based on the centerlines is proposed to segment retinal blood vessels. Hessian-based multiscale vascular enhancement filtering is used to display the vessel structures in maximum intensity projection. Random walk algorithm provides a unique and quality solution, which is robust to weak object boundaries. Seed groups in the random walk segmentation are labeled according to the centerlines, which are extracted by using the divergence of the normalized gradient vector field and the morphological method. Experiments of the proposed method are implemented on the publicly available STARE (the Structured Analysis of the Retina) database. The results are compared to other existing retinal blood vessel segmentation methods with respect to the accuracy, sensitivity, and specificity, and the proposed method is proved to be more sensitive in detecting the retinal blood vessels in both normal and pathological areas.

scholarly journals Multichannel Retinal Blood Vessel Segmentation Based on the Combination of Matched Filter and U-Net Network

2021 ◽  
Vol 2021 ◽  
pp. 1-18
Author(s):  
Yuliang Ma ◽  
Zhenbin Zhu ◽  
Zhekang Dong ◽  
Tao Shen ◽  
Mingxu Sun ◽  
...  
Keyword(s):  
Blood Vessel ◽  
Blood Vessels ◽  
Current Problem ◽  
Matched Filter ◽  
Vessel Segmentation ◽  
Retinal Blood Vessel ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels ◽  
Vessel Enhancement ◽  
Better Than

Aiming at the current problem of insufficient extraction of small retinal blood vessels, we propose a retinal blood vessel segmentation algorithm that combines supervised learning and unsupervised learning algorithms. In this study, we use a multiscale matched filter with vessel enhancement capability and a U-Net model with a coding and decoding network structure. Three channels are used to extract vessel features separately, and finally, the segmentation results of the three channels are merged. The algorithm proposed in this paper has been verified and evaluated on the DRIVE, STARE, and CHASE_DB1 datasets. The experimental results show that the proposed algorithm can segment small blood vessels better than most other methods. We conclude that our algorithm has reached 0.8745, 0.8903, and 0.8916 on the three datasets in the sensitivity metric, respectively, which is nearly 0.1 higher than other existing methods.

scholarly journals Retinal blood vessel segmentation based on heuristic image analysis

2019 ◽  
Vol 16 (1) ◽  
pp. 227-245 ◽  
Author(s):  
Maja Braovic ◽  
Darko Stipanicev ◽  
Ljiljana Seric
Keyword(s):  
Blood Vessel ◽  
Blood Vessels ◽  
Vessel Segmentation ◽  
Optic Disk ◽  
Fundus Images ◽  
Retinal Blood Vessel ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels ◽  
Retinal Fundus Images ◽  
Retinal Fundus

Automatic analysis of retinal fundus images is becoming increasingly present today, and diseases such as diabetic retinopathy and age-related macular degeneration are getting a higher chance of being discovered in the early stages of their development. In order to focus on discovering those diseases, researchers commonly preprocess retinal fundus images in order to detect the retinal landmarks - blood vessels, fovea and the optic disk. A large number of methods for the automatic detection of retinal blood vessels from retinal fundus images already exists, but many of them are using unnecessarily complicated approaches. In this paper we demonstrate that a reliable retinal blood vessel segmentation can be achieved with a cascade of very simple image processing methods. The proposed method puts higher emphasis on high specificity (i.e. high probability that the segmented pixels actually belong to retinal blood vessels and are not false positive detections) rather than on high sensitivity. The proposed method is based on heuristically determined parametric edge detection and shape analysis, and is evaluated on the publicly available DRIVE and STARE datasets on which it achieved the average accuracy of 96.33% and 96.10%, respectively.

scholarly journals A Hybrid Method to Enhance Thick and Thin Vessels for Blood Vessel Segmentation

Diagnostics ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 2017
Author(s):  
Sonali Dash ◽  
Sahil Verma ◽  
Kavita Kavita ◽  
Md. Sameeruddin Khan ◽  
Marcin Wozniak ◽  
...  
Keyword(s):  
Blood Vessel ◽  
Hybrid Method ◽  
Noisy Data ◽  
Curvelet Transform ◽  
Vessel Segmentation ◽  
Retinal Blood Vessel ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels ◽  
Simulation Results ◽  
Ophthalmic Disease

Retinal blood vessels have been presented to contribute confirmation with regard to tortuosity, branching angles, or change in diameter as a result of ophthalmic disease. Although many enhancement filters are extensively utilized, the Jerman filter responds quite effectively at vessels, edges, and bifurcations and improves the visualization of structures. In contrast, curvelet transform is specifically designed to associate scale with orientation and can be used to recover from noisy data by curvelet shrinkage. This paper describes a method to improve the performance of curvelet transform further. A distinctive fusion of curvelet transform and the Jerman filter is presented for retinal blood vessel segmentation. Mean-C thresholding is employed for the segmentation purpose. The suggested method achieves average accuracies of 0.9600 and 0.9559 for DRIVE and CHASE_DB1, respectively. Simulation results establish a better performance and faster implementation of the suggested scheme in comparison with similar approaches seen in the literature.

scholarly journals Retinal blood vessel segmentation using a deep learning method based on modified U-NET model

2021 ◽  
Author(s):  
Sanjeewani NA ◽  
arun kumar yadav ◽  
Mohd Akbar ◽  
mohit kumar ◽  
Divakar Yadav
Keyword(s):  
Deep Learning ◽  
Blood Vessel ◽  
Blood Vessels ◽  
Automatic Segmentation ◽  
Vessel Segmentation ◽  
Great Success ◽  
Retinal Blood Vessel ◽  
Data Set ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels

<div>Automatic retinal blood vessel segmentation is very crucial to ophthalmology. It plays a vital role in the early detection of several retinal diseases such as Diabetic Retinopathy, hypertension, etc. In recent times, deep learning based methods have attained great success in automatic segmentation of retinal blood vessels from images. In this paper, a U-NET based architecture is proposed to segment the retinal blood vessels from fundus images of the eye. Furthermore, 3 pre-processing algorithms are also proposed to enhance the performance of the system. The proposed architecture has provided significant results. On the basis of experimental evaluation on the publicly available DRIVE data set, it has been observed that the average accuracy (Acc) is .9577, sensitivity (Se) is .7436, specificity (Sp) is .9838 and F1-score is .7931. The proposed system outperforms all recent state of art approaches mentioned in the literature.</div>

scholarly journals Spider U-Net: Incorporating Inter-Slice Connectivity Using LSTM for 3D Blood Vessel Segmentation

2021 ◽  
Vol 11 (5) ◽  
pp. 2014
Author(s):  
Kyeorye Lee ◽  
Leonard Sunwoo ◽  
Tackeun Kim ◽  
Kyong Joon Lee
Keyword(s):  
Blood Vessel ◽  
Blood Vessels ◽  
Short Term Memory ◽  
Feeding Strategy ◽  
Model Performance ◽  
Vessel Segmentation ◽  
Medical Image Segmentation ◽  
Convolutional Network ◽  
Blood Vessel Segmentation ◽  
Public Datasets

Blood vessel segmentation (BVS) of 3D medical imaging such as computed tomography and magnetic resonance angiography (MRA) is an essential task in the clinical field. Automation of 3D BVS using deep supervised learning is being researched, and U-Net-based approaches, which are considered as standard for medical image segmentation, are proposed a lot. However, the inherent characteristics of blood vessels, e.g., they are complex and narrow, as well as the resolution and sensitivity of the imaging modalities increases the difficulty of 3D BVS. We propose a novel U-Net-based model named Spider U-Net for 3D BVS that considers the connectivity of the blood vessels between the axial slices. To achieve this, long short-term memory (LSTM), which can capture the context of the consecutive data, is inserted into the baseline model. We also propose a data feeding strategy that augments data and makes Spider U-Net stable. Spider U-Net outperformed 2D U-Net, 3D U-Net, and the fully convolutional network-recurrent neural network (FCN-RNN) in dice coefficient score (DSC) by 0.048, 0.077, and 0.041, respectively, for our in-house brain MRA dataset and also achieved the highest DSC for two public datasets. The results imply that considering inter-slice connectivity with LSTM improves model performance in the 3D BVS task.

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