scholarly journals Effects of dietary inorganic chromium supplementation on broiler growth performance: a meta-analysis

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11097
Author(s):  
Chao Feng ◽  
Hua Lin ◽  
Jie Li ◽  
Bin Xie
Keyword(s):  
Growth Performance ◽  
Publication Bias ◽  
Meta Analysis ◽  
Average Daily Gain ◽  
Weighted Average ◽  
Test Method ◽  
Sensitivity Analyses ◽  
Chromium Addition ◽  
Subgroup Analyses ◽  
Daily Gain

Background A meta-analysis was conducted to assess dietary inorganic chromium supplementation on broiler growth performance and determine if these effects are regulated by strains, sex, or contextual factors such as study area and time. Methods Eligible studies were identified by searching Web of Science, Springer, Elsevier, Science Direct, Taylor & Francis online databases. The weighted average difference with corresponding 95% confidence interval was computed with a random-effects model. We performed subgroup analyses stratified by study locations, published years, broiler sex, and strains. The publication bias was assessed with Egger’s test method. A total of nine studies were eligible for inclusion. Results The meta-analysis results indicated that inorganic chromium supplementation significantly improved the broiler’s growth performance, with a lower feed conversion ratio (FCR) and a higher average daily feed intake (ADFI). Through subgroup analyses, we found that the result of average daily gain (ADG) in Iran or published in the 2010s, the results of ADFI in Egypt, and the results of FCR in China had significant responses to chromium supplementation. We also found that Cobb 500 broilers and male broilers might be more sensitive to the addition of inorganic chromium by subgroup analyses. A model was used to obtain the amount of chromium addition under the optimal growth performance. The results showed that the adjusted ADFI and FCR presented a quadratic relationship with chromium supplementation except for average daily gain (ADG). The growth performance improved when the inorganic chromium addition ranged from 1.6 to 2.3 mg/kg. The result of sensitivity analyses showed low sensitivity and high stability. Also, there was little indication of publication bias for studies. Conclusions Our study showed that the males and Cobb 500 broilers might be more sensitive to chromium supplementation and provided more accurate inorganic chromium supplementation for broiler management practice. The fewer included studies may lead to higher heterogeneity, and no subgroup analyses of environmental stress conditions was conducted due to the lack of related information. Therefore, this study still has some limitations, and we look forward to the follow-up researches.

scholarly journals Effects of dietary chromium picolinate supplementation on broiler growth performance: A meta-analysis

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249527
Author(s):  
Chao Feng ◽  
Qiqige Wuren ◽  
Xinyu Zhang ◽  
Xiaoying Sun ◽  
Qin Na
Keyword(s):  
Environmental Stress ◽  
Growth Performance ◽  
Subgroup Analysis ◽  
Meta Analysis ◽  
Average Daily Gain ◽  
Weighted Average ◽  
Optimal Growth ◽  
Test Method ◽  
Chromium Picolinate ◽  
Chromium Addition

Objective A meta-analysis was conducted to assess the effects of dietary chromium picolinate (CrPic) supplementation on broiler growth performance and to determine whether such effects are regulated by broiler strains, sex, environmental stress, or contextual factors including study area and years. Methods Eligible studies were identified by searching the Web of Science, Springer, Elsevier, ScienceDirect, Taylor & Francis Online databases. Weighted average differences with corresponding 95% confidence intervals were computed with a random-effects model. We performed subgroup analysis stratified by study area, published years, broiler strains and sex, and environmental stress. Publication bias was assessed with Egger’s test method. A total of 15 studies eligible for inclusion. Results The results indicated that CrPic supplementation significantly improved broiler growth performance and subgroup analysis confirmed this conclusion. We also found that Ross 308 or male broilers might be more sensitive to CrPic supplementation and showed better growth performance. A model was used to obtain the amount of chromium addition under the optimal growth performance, which suggested that the maximum value of average daily gain (ADG) was reached when chromium addition was 1810 μg/kg. The results of the sensitivity analysis showed low sensitivity and high stability of the meta-analysis. Conclusions CrPic supplementation had a positive effect on the growth performance of broilers, and this meta-analysis provides a more accurate value of chromium addition, which may be beneficial for the practice of the broiler industry.

scholarly journals The effect of hydroxychloride trace minerals on the growth performance and carcass quality of grower/finisher pigs: a meta-analysis

2019 ◽  
Vol 97 (11) ◽  
pp. 4619-4624
Author(s):  
Sandra J A van Kuijk ◽  
Marc Jacobs ◽  
Coen H M Smits ◽  
Yanming Han
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Meta Analysis ◽  
Average Daily Gain ◽  
The Body ◽  
Trace Minerals ◽  
Carcass Quality ◽  
Lean Meat ◽  
Daily Gain ◽  
Mineral Sources

Abstract The current study compared the effect of hydroxychloride trace minerals (HTM) with the effect of inorganic trace minerals (ITM) on growth performance and carcass quality in grower-finisher pigs. The results of 6 studies conducted throughout Europe were combined into one meta-analysis. All included studies were performed using pigs from about 19 kg of body weight until slaughter. In all studies, 2 different mineral sources were compared, HTM and sulfates as ITM. Zn from either HTM or ITM was added at a level of 80 ppm to the diet, and Cu was added at a level of 15 ppm from the same source as Zn. In most studies, an additional treatment was included in which 20 ppm Zn was used from either source in combination with 15 ppm Cu from the same source. Diets were fed in 3 phases according to local commercial standards. The body weight, average daily gain, average daily feed intake, and gain:feed ratio were measured at the end of each phase. At the end of each study, the carcass yield, back fat thickness, and lean meat percentage were measured at commercial slaughterhouses. The meta-analysis was conducted using a MIXED model in SAS taking into account the within-study and between-study variation. The comparison was done only between HTM and ITM added at the same Zn level. No statistical differences were observed for growth performance or carcass characteristics between the mineral sources in pigs fed 20 ppm Zn. When 80 ppm Zn was used, a significant improvement in lean meat percentage was observed in pigs fed HTM compared with pigs fed ITM. In the overall study period, there was a tendency towards an increased gain:feed ratio in pigs fed 80 ppm Zn from HTM. In the last feeding phase, before slaughter gain:feed ratio and average daily gain were both significantly improved by 3.9%. In conclusion, HTM addition improved growth performance and lean meat percentage in grower-finisher pigs.

scholarly journals 358 Effects of fermented feed supplementation on pig growth performance: A meta-analysis

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 125-126
Author(s):  
Bocheng Xu ◽  
Zhi Li ◽  
Zeqing Lu ◽  
Yizhen Wang
Keyword(s):  
Growth Performance ◽  
Meta Analysis ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Growing Pigs ◽  
Feed Additives ◽  
Feed Ratio ◽  
Weaned Piglets ◽  
Fermented Feed ◽  
Subgroup Analyses

Abstract Fermented feed (FF) is recommended due to its high nutritional value and digestibility, but its effects on pig growth performance are inconsistent. This meta-analysis was conducted to quantify the effects of FF on pig growth performance. We systematically searched in PubMed and Web of Science for studies (published between January 1, 2000 and December 20, 2018) comparing the effects of FF supplementation with basal diet on the pig growth performance. The main outcomes were average daily gain (ADG), average daily feed intake (ADFI), and gain: feed ratio (G/F). Random-effects model was used to compute the weighted mean difference (WMD) and 95% confidence interval (95% CI). The robustness of the pooled estimates was determined using sensitivity and subgroup analyses. Of 1371 identified articles, 25 were eligible and were included in the meta-analysis (n = 2391 pigs). Compared with the basal diet, FF supplementation improved ADG and G/F of weaned piglets (ADG: WMD = 18.698 g/d, 95% CI: 13.925 to 23.472, P < 0.001; G/F: WMD= 0.027, 95% CI: 0.020 to 0.036, P < 0.001), growing pigs (ADG: WMD =24.436 g/d, 95% CI: 12.441 to 36.430, P < 0.001; G/F: WMD = 0.011, 95% CI: 0.003 to 0.021, P = 0.004), and finishing pigs (ADG: WMD = 42.012 g/d, 95% CI: 8.799 to 75.226, P = 0.015; G/F: WMD = 0.018, 95% CI: 0.004 to 0.032, P = 0.014), but had no effect on ADFI (P > 0.05). The subgroup analyses revealed that fermented feed ingredients could boost the growth performance of weaned piglets and growing pigs. Moreover, the fermented feed additives promoted growth at all stages. Our study supports FF can enhance pig growth performance. To our knowledge, this is the first meta-analysis on the topic to provide production strategies for FF application in pig industry.

scholarly journals Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs

Toxins ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 604
Author(s):  
Zhong-Xing Rao ◽  
Mike D. Tokach ◽  
Jason C. Woodworth ◽  
Joel M. DeRouchey ◽  
Robert D. Goodband ◽  
...  
Keyword(s):  
Growth Performance ◽  
Linear Response ◽  
Animal Feed ◽  
Average Daily Gain ◽  
Fumonisin B1 ◽  
Nursery Pigs ◽  
Feed Production ◽  
Dietary Treatments ◽  
Daily Gain ◽  
Effect Of Feeding

Fumonisin contamination in corn is an emerging issue in animal feed production. Fumonisin disrupts the metabolism of sphingolipids and reduces growth performance. This experiment was conducted to determine the effect of feeding fumonisin-contaminated corn on growth performance and sphinganine (SA) to sphingosine (SO) ratios of 9 to 28 kg pigs. A total of 350 pigs, were used with 5 pigs/pen and 14 pens/treatment. Dietary treatments contained fumonisin-contaminated corn (50 mg/kg of fumonisin B1 + B2) blended with low fumonisin corn (10 mg/kg of fumonisin B1 + B2) to provide dietary fumonisin concentrations of 7.2, 14.7, 21.9, 32.7, and 35.1 mg/kg. From day 0 to 28, increasing fumonisin concentration decreased (linear, p < 0.001) average daily gain, average daily feed intake (linear, p = 0.055), and gain:feed ratio (linear, p = 0.016). Although these response criteria tested linear, the greatest reduction in performance was in pigs fed with 32.7 and 35.1 mg/kg of fumonisin (B1 + B2). Increasing fumonisin concentration increased the serum SA:SO ratio (linear, p < 0.001) on day 14 and 28. In summary, for 9 to 28 kg nursery pigs, increasing fumonisin linearly decreased average daily gain and gain:feed ratio. However, despite the linear response, diets containing up to 21.9 mg/kg of fumonisin did not have as dramatic a decrease in growth performance as those fed more than 32.7 mg/kg. Further research is warranted to determine the effect of fumonisin concentrations between 21.9 and 32.7 mg/kg.

scholarly journals Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xujia Liu ◽  
Zehua Jiang ◽  
Guihua Zhang ◽  
Tsz Kin Ng ◽  
Zhenggen Wu
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Fixed Effects ◽  
Literature Search ◽  
Meta Analysis ◽  
Sensitivity Analyses ◽  
Fixed Effects Models ◽  
Type 2 Dm ◽  
Subgroup Analyses

Abstract Background Genetic association of uncoupling proteins (UCPs) variants with the susceptibility of diabetic retinopathy (DR) in diabetes mellitus (DM) patients has been reported but with controversy. Here we aimed to conduct a meta-analysis to confirm the association of different UCPs variants with DR. Methods Three databases (Medline Ovid, Embase Ovid and CENTRAL) were applied in the literature search. Five genetic models, including allelic, homozygous, heterozygous, dominant and recessive models, were evaluated. Odds ratios (OR) were estimated under the random or fixed-effects models. Subgroup analyses, publication bias and sensitivity analyses were also conducted. Results Eleven studies on 2 UCPs variants (UCP1 rs1800592 and UCP2 rs659366) were included. Our meta-analysis showed that UCP1 rs1800592 was not associated with DR in type-2 DM patients, and UCP2 rs659366 also showed no association with DR. In the subgroup analyses on the stage of DR, allele G of UCP1 rs1800592 significantly increased the susceptibility of proliferative diabetic retinopathy (PDR) in type-2 DM patients in the allelic (OR = 1.26, P = 0.03) and homozygous models (OR = 1.60, P = 0.04). Subgroup analysis on ethnicity did not found any significant association of rs1800592 and rs659366 with DR. Conclusion Our meta-analysis confirmed the association of UCP1 rs1800592 variant with PDR in patients with type-2 DM, suggesting its potential as a genetic marker for PDR prediction in population screening.

scholarly journals A meta-analysis of genome-wide association studies for average daily gain and lean meat percentage in two Duroc pig populations

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shenping Zhou ◽  
Rongrong Ding ◽  
Fanming Meng ◽  
Xingwang Wang ◽  
Zhanwei Zhuang ◽  
...  
Keyword(s):  
Candidate Genes ◽  
Growth And Development ◽  
Genetic Architecture ◽  
Association Studies ◽  
Meta Analysis ◽  
Average Daily Gain ◽  
Genome Wide Association ◽  
Genome Wide Association Studies ◽  
Genome Wide ◽  
Daily Gain

Abstract Background Average daily gain (ADG) and lean meat percentage (LMP) are the main production performance indicators of pigs. Nevertheless, the genetic architecture of ADG and LMP is still elusive. Here, we conducted genome-wide association studies (GWAS) and meta-analysis for ADG and LMP in 3770 American and 2090 Canadian Duroc pigs. Results In the American Duroc pigs, one novel pleiotropic quantitative trait locus (QTL) on Sus scrofa chromosome 1 (SSC1) was identified to be associated with ADG and LMP, which spans 2.53 Mb (from 159.66 to 162.19 Mb). In the Canadian Duroc pigs, two novel QTLs on SSC1 were detected for LMP, which were situated in 3.86 Mb (from 157.99 to 161.85 Mb) and 555 kb (from 37.63 to 38.19 Mb) regions. The meta-analysis identified ten and 20 additional SNPs for ADG and LMP, respectively. Finally, four genes (PHLPP1, STC1, DYRK1B, and PIK3C2A) were detected to be associated with ADG and/or LMP. Further bioinformatics analysis showed that the candidate genes for ADG are mainly involved in bone growth and development, whereas the candidate genes for LMP mainly participated in adipose tissue and muscle tissue growth and development. Conclusions We performed GWAS and meta-analysis for ADG and LMP based on a large sample size consisting of two Duroc pig populations. One pleiotropic QTL that shared a 2.19 Mb haplotype block from 159.66 to 161.85 Mb on SSC1 was found to affect ADG and LMP in the two Duroc pig populations. Furthermore, the combination of single-population and meta-analysis of GWAS improved the efficiency of detecting additional SNPs for the analyzed traits. Our results provide new insights into the genetic architecture of ADG and LMP traits in pigs. Moreover, some significant SNPs associated with ADG and/or LMP in this study may be useful for marker-assisted selection in pig breeding.

scholarly journals Risk of dementia in gout and hyperuricaemia: a meta-analysis of cohort studies

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e041680
Author(s):  
Shu-Yue Pan ◽  
Rui-Juan Cheng ◽  
Zi-Jing Xia ◽  
Qiu-Ping Zhang ◽  
Yi Liu
Keyword(s):  
Cohort Studies ◽  
Quality Assessment ◽  
Publication Bias ◽  
Data Extraction ◽  
Meta Analysis ◽  
Sensitivity Analyses ◽  
Cochrane Library ◽  
Crystal Formation ◽  
Medical Subject Headings ◽  
Eligibility Criteria

ObjectivesGout, characterised by hyperuricaemia with monosodium urate crystal formation and inflammation, is the most common inflammatory arthritis in adults. Recent studies have found that elevated uric acid levels are related to the occurrence of dementia. We conducted a study to investigate the association between dementia and gout or hyperuricaemia.DesignSystematic review and meta-analysis of cohort studies.Data sourcesStudies were screened from inception to 28 June 2019 by searching Medline, Embase and the Cochrane Library databases.Eligibility criteriaCohort studies comparing the risk of dementia in patients with gout and hyperuricaemia versus non-gout and non-hyperuricaemia controls were enrolled.Data extraction and analysisTwo reviewers separately selected studies and extracted data using the Medical Subject Headings without restriction on languages or countries. The adjusted HRs were pooled using the DerSimonian and Laird random effects model. Sensitivity analyses were conducted to evaluate the stability of the results. Publication bias was evaluated using Egger’s and Begg’s tests. Quality assessment was performed according to the Newcastle-Ottawa Scale.ResultsFour cohort studies that met the inclusion criteria were included in our meta-analysis. We found that gout and hyperuricaemia did not increase the risk of dementia, with a pooled HR of 0.94 (95% CI 0.69 to 1.28), but might decrease the risk of Alzheimer’s disease (AD), with a pooled HR of 0.78 (95% CI 0.64 to 0.95). There was little evidence of publication bias. Quality assessment of the included studies was high (range: 6–8 points).ConclusionsOur study shows that gout and hyperuricaemia do not increase the risk of dementia. However, gout and hyperuricaemia might have a protective effect against AD. Due to the limited number of research articles, more investigations are needed to demonstrate the potential relationship between dementia and gout or hyperuricaemia.

scholarly journals Effect of Zinc Source and Level on Growth Performance and Zinc Status of Weaned Piglets

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 2030
Author(s):  
Anna Szuba-Trznadel ◽  
Anna Rząsa ◽  
Tomasz Hikawczuk ◽  
Bogusław Fuchs
Keyword(s):  
Zinc Oxide ◽  
Growth Performance ◽  
Average Daily Gain ◽  
Environmental Damage ◽  
Weaned Piglets ◽  
Group Iii ◽  
Group I ◽  
Therapeutic Doses ◽  
Daily Gain ◽  
Excessive Accumulation

The aim of this study was to evaluate the effect of zinc (Zn) supplementation in different commercial forms on the growth performance, health status, and Zn balance of weaners in field conditions. The animals were fed pre-starter (from the 28th to 47th day of life) and starter (from the 48th to 74th day of life) mixtures differing in Zn form and concentration. Group I was given ZnSO4 at 150 mg kg−1; Group II received pre-starter zinc oxide (ZnO) at 3000 mg kg−1 and starter at 150 mg kg−1; and Group III was given 150 mg kg−1 of zinc oxide nanoparticles (nZnO). We found that the average daily gain in Group I was significantly lower, compared to Groups II and III. A commonly accepted level of Zn (150 mg kg−1) as nZnO can be recommended, instead of therapeutic doses of Zn preparations with the same efficiency. Moreover, a lower level of Zn in the diet can prevent the excessive accumulation of this element in waste and, thus, reduce environmental damage.

scholarly journals Methane emissions and growth performance of young Nellore bulls fed crude glycerine- v. fibre-based energy ingredients in low or high concentrate diets

2016 ◽  
Vol 154 (7) ◽  
pp. 1280-1290 ◽  
Author(s):  
J. F. LAGE ◽  
E. SAN VITO ◽  
R. A. REIS ◽  
E. E. DALLANTONIA ◽  
L. R. SIMONETTI ◽  
...  
Keyword(s):  
Growth Performance ◽  
Dry Matter ◽  
Reference Group ◽  
Average Daily Gain ◽  
Methane Emissions ◽  
Crude Glycerine ◽  
Soybean Hulls ◽  
Feeding Regimes ◽  
Concentrate Level ◽  
Daily Gain

SUMMARYA total of 70 Nellore bulls (18 ± 3 months of age) were used to determine the effects of crude glycerine (CG) replacing starch- v. fibre-based energy ingredients in low (LC; 0·40 concentrate) or high concentrate (HC; 0·60 concentrate) – on a dry matter (DM) basis – on DM intake (DMI), methane emissions and growth. Ten bulls were slaughtered (reference group) to obtain the carcass gain (CrG). The 60 remaining bulls (374 ± 24·5 kg) were allocated to a 2 × 3 factorial arrangement (two concentrate levels, LC or HC; and three feeding regimes, FR). The FR were: CO – without CG and maize as an ingredient of concentrate; CGM – inclusion of CG (0·10 of DM) replacing maize in the concentrate; and CGSH – inclusion of CG (0·10 of DM) replacing soybean hulls (SH) in the concentrate. Bulls fed LC or HC had similar DMI (kg/d) and growth. The DMI and average daily gain (ADG) were similar among FR. Concentrate level and FR tended to interact for methane emissions (g) per kg DMI. Bulls fed CGM had a greater G : F (g CrG/kg DMI) than those fed CO or CGSH diets. Increasing dietary concentrate (0·40–0·60) did not affect intake, methane emissions, or growth. Inclusion of CG in diets to replace SH in LC diets tended to decrease methane emissions from animals. When CG replaces SH in the diets, CrG and G:F (g CrG/kg DMI) are decreased compared with bulls fed CGM.

scholarly journals Effects of coated and noncoated steroidal implants on growth performance, carcass characteristics, and serum estradiol-17β concentrations of finishing Holstein steers

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Pedro H V Carvalho ◽  
Mariana F Westphalen ◽  
Jonathan A Campbell ◽  
Tara L Felix
Keyword(s):  
Growth Performance ◽  
Animal Health ◽  
Average Daily Gain ◽  
Carcass Characteristics ◽  
Feed Ratio ◽  
Serum Estradiol ◽  
Trenbolone Acetate ◽  
Coated Implant ◽  
Daily Gain ◽  
Estradiol 17Β

Abstract The objectives of the study were to determine the effect of coated or noncoated hormone implants on growth performance, carcass characteristics, and serum estradiol-17β (E2) concentrations of Holstein steers fed a grain-based diet for 112 d. Seventy-nine Holstein steers [average initial body weight (BW) = 452 ± 5.5 kg] were stratified by BW and allotted to one of two treatments: 1) Holstein steers implanted with a coated implant containing 200 mg of trenbolone acetate (TBA) and 40 mg E2 (Revalor-XS (Merck Animal Health; Summit, NJ)] on day 0 (XS) or 2) Holstein steers implanted two times (days 0 and 56) with a noncoated implant containing 80 mg of TBA and 16 mg of E2 [(2IS) Revalor-IS (Merck Animal Health)]. Data were analyzed using the MIXED procedure of SAS (SAS Inst. Inc., Cary, NC). There was no effect (P ≥ 0.71) of implant strategy on initial, middle, and final BW. No effect (P ≥ 0.12) of implant strategy was observed on average daily gain, dry matter intake, or gain-to-feed ratio. There were no effects (P ≥ 0.11) of implant strategy on carcass characteristics. There was an implant × day interaction (P &lt; 0.01) for the circulation of serum E2 concentrations. Serum E2 concentration increased similarly 14 d after Holstein steers were implanted, regardless of implant strategy. At 28 d, after steers were implanted, steers in the XS group had less serum E2 concentration than Holstein steers in the 2IS group. However, at 56 d after the first implantation, both groups, once again, had similar serum E2 concentrations and E2 concentrations were less on day 56 than day 28 for both strategies. Holstein steers implanted with 2IS had greater serum E2 concentration on day 70 and E2 concentrations remained greater than serum E2 of Holstein steers implanted XS for the duration of the trial (day 112). In summary, there was no effect of coated or two doses of noncoated implant on growth performance or carcass characteristics of Holstein steers.

Sign in / Sign up

Export Citation Format

Share Document