scholarly journals Reductive Amination of Aldehydes with Sodium Borohydride-Silica Gel System

2013 ◽  
Vol 2 (S1) ◽  
Keyword(s):  
Silica Gel ◽  
Sodium Borohydride ◽  
Reductive Amination ◽  
Gel System

One-Pot Reductive Amination of Carbonyl Compounds Using Sodium Borohydride–Amberlyst 15

2010 ◽  
Vol 40 (7) ◽  
pp. 951-956 ◽  
Author(s):  
Heshmatollah Alinezhad ◽  
Mahmood Tajbakhsh ◽  
Nastaran Mahdavi
Keyword(s):  
Sodium Borohydride ◽  
Carbonyl Compounds ◽  
Reductive Amination ◽  
One Pot ◽  
Amberlyst 15

Selective oxidation of benzylic and allylic alcohols with NaOCl/silica gel system

2009 ◽  
Vol 6 (2) ◽  
pp. 288-292 ◽  
Author(s):  
H. Alinezhad ◽  
M. Tajbakhsh ◽  
R. Soleimani
Keyword(s):  
Selective Oxidation ◽  
Silica Gel ◽  
Allylic Alcohols ◽  
Gel System

scholarly journals Antimicrobial and antimycobacterial activities of aliphatic amines derived from vanillin

2015 ◽  
Vol 93 (11) ◽  
pp. 1305-1311 ◽  
Author(s):  
Alyssa E. Patterson ◽  
Andrew J. Flewelling ◽  
Trevor N. Clark ◽  
Stephen J. Geier ◽  
Christopher M. Vogels ◽  
...  
Keyword(s):  
Molecular Structure ◽  
Mycobacterium Tuberculosis ◽  
Sodium Borohydride ◽  
Reductive Amination ◽  
Antimycobacterial Activity ◽  
Antibiotic Activity ◽  
Primary Amines ◽  
X Ray Diffraction ◽  
X Ray ◽  
Boron Substitution

Ten lipophilic amines were prepared from the reductive amination of vanillin and the corresponding primary amines using sodium borohydride in methanol. All compounds have been obtained elementally pure and an X-ray diffraction study on the 4-n-butylaniline derivative has confirmed the molecular structure. Whilst the overall antibiotic activity of the derivatives was low, some of these compounds, particularly the boronate ester 2-methoxy-4-((2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylamino)methyl)phenol (7), showed a promising degree of antimycobacterial activity against Mycobacterium tuberculosis H37Ra, where activity seemed to vary by the position of the boron substitution on the aniline ring.

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