DEVELOPMENT AND VALIDATION OF A FECAL PCR ASSAY FOR NOTOEDRES CATI AND APPLICATION TO NOTOEDRIC MANGE CASES IN BOBCATS (LYNX RUFUS) IN NORTHERN CALIFORNIA, USA

2013 ◽  
Vol 49 (2) ◽  
pp. 303-311 ◽  
Author(s):  
Nicole Stephenson ◽  
Deana Clifford ◽  
S. Joy Worth ◽  
Laurel E. K. Serieys ◽  
Janet Foley
Keyword(s):  
Lynx Rufus ◽  
Northern California ◽  
Pcr Assay ◽  
Notoedres Cati ◽  
Development And Validation ◽  
Notoedric Mange

A synthetic review of notoedres species mites and mange

Parasitology ◽  
2016 ◽  
Vol 143 (14) ◽  
pp. 1847-1861 ◽  
Author(s):  
J. FOLEY ◽  
L. E. K. SERIEYS ◽  
N. STEPHENSON ◽  
S. RILEY ◽  
C. FOLEY ◽  
...  
Keyword(s):  
Close Contact ◽  
Systemic Disease ◽  
Severe Disease ◽  
Epidemiological Studies ◽  
Host Population ◽  
Disease Treatment ◽  
Notoedres Cati ◽  
Immunological Factors ◽  
Population Treatment ◽  
Notoedric Mange

SUMMARYNotoedric mange, caused by obligately parasitic sarcoptiform Notoedres mites, is associated with potentially fatal dermatitis with secondary systemic disease in small mammals, felids and procyonids among others, as well as an occasional zoonosis. We describe clinical spectra in non-chiropteran hosts, review risk factors and summarize ecological and epidemiological studies. The genus is disproportionately represented on rodents. Disease in felids and procyonids ranges from very mild to death. Knowledge of the geographical distribution of the mites is highly inadequate, with focal hot spots known for Notoedres cati in domestic cats and bobcats. Predisposing genetic and immunological factors are not known, except that co-infection with other parasites and anticoagulant rodenticide toxicoses may contribute to severe disease. Treatment of individual animals is typically successful with macrocytic lactones such as selamectin, but herd or wildlife population treatment has not been undertaken. Transmission requires close contact and typically is within a host species. Notoedric mange can kill half all individuals in a population and regulate host population below non-diseased density for decades, consistent with frequency-dependent transmission or spillover from other hosts. Epidemics are increasingly identified in various hosts, suggesting global change in suitable environmental conditions or increased reporting bias.

scholarly journals Correction for Hilbert et al., Development and Validation of a Highly Accurate Quantitative Real-Time PCR Assay for Diagnosis of Bacterial Vaginosis

2016 ◽  
Vol 54 (7) ◽  
pp. 1930-1930 ◽  
Author(s):  
David W. Hilbert ◽  
William L. Smith ◽  
Sean G. Chadwick ◽  
Geoffrey Toner ◽  
Eli Mordechai ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Real Time ◽  
Real Time Pcr ◽  
Quantitative Real Time Pcr ◽  
Pcr Assay ◽  
Development And Validation
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