scholarly journals S-cone photoreceptors in the primate retina are functionally distinct from L and M cones

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Jacob Baudin ◽  
Juan M Angueyra ◽  
Raunak Sinha ◽  
Fred Rieke

Daylight vision starts with signals in three classes of cone photoreceptors sensitive to short (S), middle (M), and long (L) wavelengths. Psychophysical studies show that perceptual sensitivity to rapidly varying inputs differs for signals originating in S cones versus L and M cones; notably, S-cone signals appear perceptually delayed relative to L- and M-cone signals. These differences could originate in the cones themselves or in the post-cone circuitry. To determine if the cones could contribute to these and related perceptual phenomena, we compared the light responses of primate S, M, and L cones. We found that S cones generate slower light responses than L and M cones, show much smaller changes in response kinetics as background-light levels increase, and are noisier than L and M cones. It will be important to incorporate these differences into descriptions of how cone signaling shapes human visual perception.

2019 ◽  
Vol 151 (11) ◽  
pp. 1287-1299 ◽  
Author(s):  
Norianne T. Ingram ◽  
Alapakkam P. Sampath ◽  
Gordon L. Fain

We describe the first extensive study of voltage-clamp current responses of cone photoreceptors in unlabeled, dark-adapted mouse retina using only the position and appearance of cone somata as a guide. Identification was confirmed from morphology after dye filling. Photocurrents recorded from wild-type mouse cones were biphasic with a fast cone component and a slower rod component. The rod component could be eliminated with dim background light and was not present in mouse lines lacking the rod transducin-α subunit (Gnat1−/−) or connexin 36 (Cx36−/−). Cones from Gnat1−/− or Cx36−/− mice had resting membrane potentials between −45 and −55 mV, peak photocurrents of 20–25 picoamps (pA) at a membrane potential Vm = −50 mV, sensitivities 60–70 times smaller than rods, and a total membrane capacitance two to four times greater than rods. The rate of activation (amplification constant) was largely independent of the brightness of the flash and was 1–2 s−2, less than half that of rods. The role of Ca2+-dependent transduction modulation was investigated by recording from cones in mice lacking rod transducin (Gnat1), recoverin, and/or the guanylyl-cyclase–activating proteins (GCAPs). In confirmation of previous results, responses of Gnat1−/−;Gcaps−/− cones and triple-mutant Gnat1−/−;Gcaps−/−;Rv−/− cones recovered more slowly both to light flashes and steps and were more sensitive than cones expressing the GCAPs. Cones from all four mouse lines showed significant recovery and escaped saturation even in bright background light. This recovery occurred too rapidly to be caused by pigment bleaching or metaII decay and appears to reflect some modulation of response inactivation in addition to those produced by recoverin and the GCAPs. Our experiments now make possible a more detailed understanding of the cellular physiology of mammalian cone photoreceptors and the role of conductances in the inner and outer segment in producing cone light responses.


1992 ◽  
Vol 8 ◽  
pp. 1-16 ◽  
Author(s):  
John Geake

The beauty and freshness of fractal geometry suggests that once again we are at the start of science and mathematics… women and men will look back on this era much as we look back to the early Greeks. (Barnsley, 1989, p. 5)Such enthusiasm for a perceived new paradigm in the mathematical sciences is beginning to emerge within broader educational contexts (Devaney & Keen, 1989; Egnatoff, 1989; Geake, 1990a & 1990b). Much of the interest in fractal geometry has focussed on its ability to describe complex natural phenomena (Mandelbrot, 1983 & 1990; Pickover, 1987; Barnsley, 1988). Recent investigations into the visual perception of natural imagery have used fractal mathematics in describing the characteristics of such perception (Pentland, 1984; Field, 1987; Peli, 1990). This study examined human visual perception of the fractal form found in the natural environment. Specifically, this research project examined how exposure to a program of fractal computer graphics affected the perceptual sensitivity of primary school children to the natural visual environment. The underpinning rationale was to address a long standing challenge of Linke (1980) to develop a stronger theoretical basis for environmental education in Australia.


1993 ◽  
Vol 26 (6) ◽  
pp. 825-842 ◽  
Author(s):  
Yung-Sheng Chen ◽  
Shih-Liang Chang ◽  
Wen-Hsing Hsu

Nanophotonics ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 41-74
Author(s):  
Bernard C. Kress ◽  
Ishan Chatterjee

AbstractThis paper is a review and analysis of the various implementation architectures of diffractive waveguide combiners for augmented reality (AR), mixed reality (MR) headsets, and smart glasses. Extended reality (XR) is another acronym frequently used to refer to all variants across the MR spectrum. Such devices have the potential to revolutionize how we work, communicate, travel, learn, teach, shop, and are entertained. Already, market analysts show very optimistic expectations on return on investment in MR, for both enterprise and consumer applications. Hardware architectures and technologies for AR and MR have made tremendous progress over the past five years, fueled by recent investment hype in start-ups and accelerated mergers and acquisitions by larger corporations. In order to meet such high market expectations, several challenges must be addressed: first, cementing primary use cases for each specific market segment and, second, achieving greater MR performance out of increasingly size-, weight-, cost- and power-constrained hardware. One such crucial component is the optical combiner. Combiners are often considered as critical optical elements in MR headsets, as they are the direct window to both the digital content and the real world for the user’s eyes.Two main pillars defining the MR experience are comfort and immersion. Comfort comes in various forms: –wearable comfort—reducing weight and size, pushing back the center of gravity, addressing thermal issues, and so on–visual comfort—providing accurate and natural 3-dimensional cues over a large field of view and a high angular resolution–vestibular comfort—providing stable and realistic virtual overlays that spatially agree with the user’s motion–social comfort—allowing for true eye contact, in a socially acceptable form factor.Immersion can be defined as the multisensory perceptual experience (including audio, display, gestures, haptics) that conveys to the user a sense of realism and envelopment. In order to effectively address both comfort and immersion challenges through improved hardware architectures and software developments, a deep understanding of the specific features and limitations of the human visual perception system is required. We emphasize the need for a human-centric optical design process, which would allow for the most comfortable headset design (wearable, visual, vestibular, and social comfort) without compromising the user’s sense of immersion (display, sensing, and interaction). Matching the specifics of the display architecture to the human visual perception system is key to bound the constraints of the hardware allowing for headset development and mass production at reasonable costs, while providing a delightful experience to the end user.


Author(s):  
Denis Hilton

Attribution processes appear to be an integral part of human visual perception, as low-level inferences of causality and intentionality appear to be automatic and are supported by specific brain systems. However, higher-order attribution processes use information held in memory or made present at the time of judgment. While attribution processes about social objects are sometimes biased, there is scope for partial correction. This chapter reviews work on the generation, communication, and interpretation of complex explanations, with reference to explanation-based models of text understanding that result in situation models of narratives. It distinguishes between causal connection and causal selection, and suggests that a factor will be discounted if it is not perceived to be connected to the event and backgrounded if it is perceived to be causally connected to that event, but is not selected as relevant to an explanation. The final section focuses on how interpersonal explanation processes constrain causal selection.


2017 ◽  
Author(s):  
Jeremy Cole ◽  
David Reitter ◽  
Yanxi Liu

Most literature on symmetry perception has focused on bilateralreflection symmetry with some suggesting that it isthe only type of symmetry humans can perceive (Wilson &Wilkinson, 2002). Using image stimuli generated from themathematically well-defined seventeen wallpaper groups, thisstudy demonstrates that humans can discriminate various symmetriesfound in 2D wallpaper patterns (Liu, Hel-Or, Kaplan,Van Gool, et al., 2010). Furthermore, the results demonstratethe features which contribute to wallpaper pattern perception.All wallpaper groups but one were found to be reliably distinguishable(p < 0:05). Additionally, as wallpaper patterns canbe arranged in a hierarchy, we propose a metric to quantify thesimilarity of their perception using the shortest path in this hierarchy.This subgroup distance was found to be a factor in alikely model of pattern perception.


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