Fish Pedicure: A Risky Aesthetic Treatment for Tourists

Gianluca Nazzaro; Francesca Germiniasi; Stefano Veraldi

doi:10.7547/19-006

Fish Pedicure: A Risky Aesthetic Treatment for Tourists

Journal of the American Podiatric Medical Association ◽

10.7547/19-006 ◽

2020 ◽

Vol 110 (5) ◽

Author(s):

Gianluca Nazzaro ◽

Francesca Germiniasi ◽

Stefano Veraldi

Keyword(s):

Stratum Corneum ◽

Hot Springs ◽

Health Workers ◽

Skin Infections ◽

Fish Pedicure

Fish pedicure is considered to be an aesthetic treatment, first conceived in Turkey, in Kangal Hot Springs. These hot waters are rich in two species of fish of the Cyprinidae family that feed on the stratum corneum layer of patients with psoriasis. This treatment was later adapted to many spa resorts for “fish pedicure.” In this article, we performed a review of the skin infections already reported, explaining why this procedure, performed usually during summer holidays by tourists, is not risk free and should be discouraged by health workers.

Download Full-text

A DSG1 Frameshift Variant in a Rottweiler Dog with Footpad Hyperkeratosis

Genes ◽

10.3390/genes11040469 ◽

2020 ◽

Vol 11 (4) ◽

pp. 469

Author(s):

Katherine A. Backel ◽

Sarah Kiener ◽

Vidhya Jagannathan ◽

Margret L. Casal ◽

Tosso Leeb ◽

...

Keyword(s):

Atopic Dermatitis ◽

Stratum Corneum ◽

Candidate Genes ◽

Mutant Allele ◽

Skin Infections ◽

Loss Of Function ◽

Palmoplantar Keratoderma ◽

Gene Encoding ◽

Single Male ◽

Ear Infections

A single male Rottweiler dog with severe footpad hyperkeratosis starting at an age of eight weeks was investigated. The hyperkeratosis was initially restricted to the footpads. The footpad lesions caused severe discomfort to the dog and had to be trimmed under anesthesia every 8–10 weeks. Histologically, the epidermis showed papillated villous projections of dense keratin in the stratum corneum. Starting at eight months of age, the patient additionally developed signs consistent with atopic dermatitis and recurrent bacterial skin and ear infections. Crusted hyperkeratotic plaques developed at sites of infection. We sequenced the genome of the affected dog and compared the data to 655 control genomes. A search for variants in 32 candidate genes associated with human palmoplantar keratoderma (PPK) revealed a single private protein-changing variant in the affected dog. This was located in the DSG1 gene encoding desmoglein 1. Heterozygous monoallelic DSG1 variants have been reported in human patients with striate palmoplantar keratoderma I (SPPK1), while biallelic DSG1 loss of function variants in humans lead to a more pronounced condition termed severe dermatitis, multiple allergies, and metabolic wasting (SAM) syndrome. The identified canine variant, DSG1:c.2541_2545delGGGCT, leads to a frameshift and truncates about 20% of the coding sequence. The affected dog was homozygous for the mutant allele. The comparative data on desmoglein 1 function in humans suggest that the identified DSG1 variant may have caused the footpad hyperkeratosis and predisposition for allergies and skin infections in the affected dog.

Download Full-text

Conventional and natural compounds for the treatment of dermatophytosis

Medical Mycology ◽

10.1093/mmy/myz116 ◽

2019 ◽

Vol 58 (6) ◽

pp. 707-720

Author(s):

Ana I Lopes ◽

Freni K Tavaria ◽

Manuela E Pintado

Keyword(s):

Side Effects ◽

Stratum Corneum ◽

State Of The Art ◽

Pathogenic Fungi ◽

Resistance Mechanisms ◽

Mechanisms Of Action ◽

Antifungal Drugs ◽

Skin Infections ◽

Superficial Skin ◽

High Treatment

Abstract Dermatophytes are a group of pathogenic fungi that exclusively infect the stratum corneum of the skin, nails, and hair, causing dermatophytosis. Superficial skin infections caused by dermatophytes have increased in the last decades. There are conventional antifungals that treat these infections, such as terbinafine, fluconazole, and others. However, the limitations of these treatments (resistance, side effects and toxicity) along with the increasing over-prescription, the misuse of these antifungals and the high treatment costs led to the search for new, alternative, natural-based antifungal drugs. These have multiple mechanisms of action, which works to their advantage, making it difficult for a fungus to create resistance mechanisms against all of them at the same time. The main objective of this work is to provide a state-of-the-art review on dermatophytes, dermatophytosis, and the existing treatments, both conventional and natural, such as chitosan and essential oils.

Download Full-text

Reducing recurrence of bacterial skin infections in Aboriginal children in rural communities: new ways of thinking, new ways of working

Australian Journal of Primary Health ◽

10.1071/py16135 ◽

2017 ◽

Vol 23 (3) ◽

pp. 229 ◽

Cited By ~ 6

Author(s):

Susan Thomas ◽

Kristy Crooks ◽

Kylie Taylor ◽

Peter D. Massey ◽

Ruth Williams ◽

...

Keyword(s):

Rural Communities ◽

Treatment Guidelines ◽

Health Workers ◽

School Attendance ◽

School Staff ◽

Sociocultural Factors ◽

Skin Infections ◽

Community Members ◽

Aboriginal Children ◽

Bacterial Skin Infections

Reports from health workers, school staff and community members in rural NSW suggested that bacterial skin infections are a significant health issue for Aboriginal children and their families, affecting quality of life and contributing to poor school attendance. Current NSW treatment guidelines do not incorporate important sociocultural factors or ways of living in Aboriginal communities. The aim of this qualitative study was to gain a deeper understanding of the experience of parents and carers of Aboriginal children affected by skin infections and of other community members, health workers and school staff, and what actions have been considered successful or unsuccessful in reducing the recurrence of infection. This study used a Participatory Action Research methodology. Interviews and focus groups were conducted with 38 health workers and managers, school staff, community members and parents and carers. Themes that emerged included: (i) skin infections have become normalised; (ii) skin infections are, in part, a consequence of transgenerational trauma; (iii) skin infections are interwoven with social determinants; (iv) families have survived but more could thrive; and (v) something can and should be done about the problem. The findings of this study will inform the development of more effective and acceptable options to reduce skin infections in Aboriginal children.

Download Full-text

PENANGANAN LIMBAH MEDIS DAN PERILAKU PETUGAS CLEANING SERVICE DI RSUD Dr. SOETOMO SURABAYA TAHUN 2016

GEMA LINGKUNGAN KESEHATAN ◽

10.36568/kesling.v14i2.243 ◽

2016 ◽

Vol 14 (2) ◽

Author(s):

Risca Anesea ◽

Erna Triastuti ◽

Ferry Kriswandana

Keyword(s):

Hepatitis B ◽

Small Proportion ◽

Hepatitis A ◽

Health Workers ◽

Medical Waste ◽

Protective Equipment ◽

Skin Infections ◽

Cross Sectional ◽

Descriptive Research ◽

Level Of Knowledge

Health workers who handle medical waste are at risk of the diseases faced because of germs from the skin infections, anthrax, meningitis, dengue, hepatitis A, Hepatitis B and C. The bacteria present in the blood are transmitted through blood. The highest risk of being infected by these diseases is when impaled by sharp or pointed object of the waste because it can damage the skin. The purpose of this study was to determine the behavior of CS officers (Cleaning Service) and the handling of medical waste in Dr. Soetomo hospital. This is a descriptive research with cross sectional approach. The collection of data was carried out through observation and interviews. The sample was 75 CS officers. Data were analyzed descriptively with table analysis.The results showed that Cleaning Services’ level of knowledge at Dr. Soetomo Hospital on handling medical waste with "Good" criteria was 90.8%. The CS attitude with "good" criteria was 88% and poor was 5.3%. CS’s behavior with "Good" criteria was 92% and "poor" was 6.7%. It can be concluded that of 75 Cleaning Service at Hospital Dr. Soetomo, most of them were well behaved and only a small proportion have poor behavior. The handling of medical waste in Dr. Soetomo hospital has been qualified in accordance with Kepmenkes No 1204 of 2004. It is recommended to conduct counseling on the importance of the use of personal protective equipment and the dangers of medical waste. Warning is also needed to officers whose work is not according to the rules. Keywords: CS Behavior, handling of medical waste

Download Full-text

Changes in corneocyte element concentrations occur in skin inner stratum corneum

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100134326 ◽

1990 ◽

Vol 48 (2) ◽

pp. 146-147

Author(s):

R. R. Warner

Keyword(s):

Stratum Corneum ◽

Human Skin ◽

Element Concentration ◽

Skin Barrier ◽

Barrier Properties ◽

Brick Wall ◽

Inorganic Elements ◽

Dry Skin ◽

Skin Biopsies ◽

Intercellular Lipid

Keratinocytes undergo maturation during their transit through the viable layers of skin, and then abruptly transform into flattened, anuclear corneocytes that constitute the cellular component of the skin barrier, the stratum corneum (SC). The SC is generally considered to be homogeneous in its structure and barrier properties, and is often shown schematically as a featureless brick wall, the “bricks” being the corneocytes, the “mortar” being intercellular lipid. Previously we showed the outer SC was not homogeneous in its composition, but contained steep gradients of the physiological inorganic elements Na, K and Cl, likely originating from sweat salts. Here we show the innermost corneocytes in human skin are also heterogeneous in composition, undergoing systematic changes in intracellular element concentration during transit into the interior of the SC.Human skin biopsies were taken from the lower leg of individuals with both “good” and “dry” skin and plunge-frozen in a stirred, cooled isopentane/propane mixture.

Download Full-text

Paracrystalline Aggregates of Psoriatic Keratin and Their Relation to Normal Keratin Structure

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100120096 ◽

1985 ◽

Vol 43 ◽

pp. 680-681

Author(s):

S. Trachtenberg ◽

P.M. Steinert ◽

B.L. Trus ◽

A.C. Steven

Keyword(s):

Cell Death ◽

Stratum Corneum ◽

Intermediate Filament ◽

Skin Disease ◽

Amorphous Matrix ◽

Terminal Differentiation ◽

Proteolytic Degradation ◽

Horny Layer ◽

Chronic Skin ◽

Chronic Skin Disease

During terminal differentiation of vertebrate epidermis, certain specific keratin intermediate filament (KIF) proteins are produced. Keratinization of the epidermis involves cell death and disruption of the cytoplasm, leaving a network of KIF embedded in an amorphous matrix which forms the outer horny layer known as the stratum corneum. Eventually these cells are shed (desquamation). Normally, the processes of differentiation, keratinization, and desquamation are regulated in an orderly manner. In psoriasis, a chronic skin disease, a hyperkeratotic stratum corneum is produced, resulting in abnormal desquamation of unusually large scales. In this disease, the normal KIF proteins are diminished in amount or absent, and other proteins more typical of proliferative epidermal cells are present. There is also evidence of proteolytic degradation of the KIF.

Download Full-text