Calcium Sulfate/Calcium Phosphate Bone Void Filler in the Treatment of Bilateral Adolescent Unicameral Calcaneal Bone Cysts: 36-Month Follow-Up

2019 ◽  
Vol 109 (5) ◽  
pp. 379-388
Author(s):  
Jeffrey C. Karr
Keyword(s):  
Calcium Phosphate ◽  
Calcium Sulfate ◽  
Platelet Rich Plasma ◽  
Open Approach ◽  
Bone Cysts ◽  
Allogenic Bone ◽  
Bone Void Filler ◽  
Calcaneal Cyst ◽  
Bone Void

A 36-month follow-up of the management of bilateral adolescent unicameral bone cysts in a high school gymnast treated with a calcium sulfate/calcium phosphate (CSCP) bone void filler (BVF) is presented. The more developed left calcaneal cyst was managed with a traditional, open approach consisting of allogenic bone graft, CSCP BVF mixed with platelet-rich plasma. The less developed right calcaneal cyst was managed with a less used approach, a percutaneous bone cortex incision with only the CSCP BVF. The rationale for the selection between the open and percutaneous approaches, long-term BVF incorporation, and positive patient outcome allowing a quick return to athletics are presented.

scholarly journals Reconstruction of anterior frontal wall and contours defects using bone substitute

2021 ◽  
pp. 34
Author(s):  
Keyword(s):  
Bone Substitute ◽  
Calcium Sulfate ◽  
Donor Site ◽  
Bone Defects ◽  
Autogenous Bone ◽  
Bone Void Filler ◽  
Custom Made ◽  
Cranial Implant ◽  
Bone Void ◽  
Orbital Area

Aim: The aim of this article is to report on the safety and long-term efficacy of Cerament® BoneVoid Filler bone substitute for repairing craniofacial bone defects. Post-traumatic cranioplasty is a complex and challenging procedure for all maxillo-craniofacial surgeons and neurosurgeons, especially when repairing large areas. The standard criterion for repairing small cranial defects is the use autogenous bone from the iliac crest or split calvarial grafts. Autogenous grafts may result in donor-site morbidity, increased surgical time, reabsorption, blood loss, and longer recovery time . Alloplastic materials used for bone repair, such as methyl methacrylate, hydroxyapatite, titanium, or porous polyethylene, are expected to have optimal properties, including easy adaptation, biocompatibility, ingrowth of new tissue, stability of shape, and low rate of reabsorption. A cranial implant should be easily shaped and positioned, allowing easy tissue growth. In very wide cranium defects the new technology is a custom made cranial implant constructed three-dimensionally with different types of materials. However, this procedure is very expensive with various infection rates depending on the kind of material used and on the chemicophysical composition of the implant. Methods: The authors report the case of a 50-year-old man with a severe deformity of the forehead-supra orbital area as a result of a previous complex fronto-facial trauma treated in an emergency Unit. Secondary correction and reconstruction of the residual deformities were performed by using Cerament® Bone Void Filler, an alloplastic biphasic material, composed of 40% hydroxyapatite, 60% calcium sulfate and the radio-contrast agent iohexol. The unique ratio of hydroxyapatite and calcium sulfate is designed to enable Cerament to resorb at the same rate that bone forms. Calcium sulfate acts as a resorbable carrier for hydroxyapatite which is highly osteoconductive, promoting bone ingrowth.It seems to be a promising bone graft substitute in the management of bony irregularities in the fronto-orbital area. Conclusion: The patient was first hospitalized as the result of a serious craniofacial trauma. One year after the first emergency cranio-orbital reconstructive operation, a marked deformity of the frontal region appeared with a “grid effect” due to the inadequate plate-bony fixation of the fractures applied during the first bony recomposition and because it was not as rigid as it should have been . A secondary surgery for deformity correction was performed. The hardware was totally removed and the bony deformity smoothed, reshaped, covered and filled using Cerament® Bone Void Filler, a biomaterial. The patient recovered with a satisfactory cranium-forehead shape, no complications, and complete disappearance of a frowning look of the fronto-orbital region. Recently, increased use of bone substitutes in the reconstruction of bone defects has been fuelled by donor site complications associated with autologous bone harvesting. Cerament® BoneVoid Filler is a biphasic and injectable bone substitute that has a highly compressive strength and the ability to promote cancellous bone healing

Calcium Sulfate Bone Void Filler: A Review and a Look Ahead

2000 ◽  
Vol 11 (4) ◽  
pp. 327-333 ◽  
Author(s):  
William S. Pietrzak ◽  
Robert Ronk
Keyword(s):  
Calcium Sulfate ◽  
Look Ahead ◽  
Bone Void Filler ◽  
Bone Void

The Treatment of Chronic Osteomyelitis with a Biodegradable Antibiotic-Impregnated Implant

2002 ◽  
Vol 10 (1) ◽  
pp. 53-60 ◽  
Author(s):  
Steven Gitelis ◽  
Gregory T. Brebach
Keyword(s):  
Dead Space ◽  
Calcium Sulfate ◽  
Bone Repair ◽  
Chronic Osteomyelitis ◽  
Attractive Alternative ◽  
Local Antibiotics ◽  
Biodegradable Implant ◽  
Bone Void Filler ◽  
Custom Made ◽  
Bone Void

The use of local antibiotics from a biodegradable implant for chronic osteomyelitis is an attractive alternative. The implant delivers high tissue levels, obliterates dead space, aids bone repair and does not need to be removed. The purpose of this paper is to review our early clinical experience with custom-made calcium sulfate (Osteoset bone void filler) antibiotic-impregnated implants.

scholarly journals Evaluation of Antibiotic-Releasing Triphasic Bone Void Filler In-Vitro

2018 ◽  
Vol 9 (4) ◽  
pp. 55 ◽  
Author(s):  
Michael Harris ◽  
Hamza Ahmed ◽  
Leslie Pace ◽  
Jon Minter ◽  
Michael Neel ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Calcium Sulfate ◽  
Minimal Effect ◽  
Time Points ◽  
Dissolution Study ◽  
Infection Treatment ◽  
Bone Void Filler ◽  
Bone Void

Bone void fillers (BVFs) containing calcium sulfate, tricalcium phosphate (TCP), and hydroxyapatite can be loaded with antibiotics for infection treatment or prevention under surgeon-directed use. The aim of this study was to characterize the handling and elution properties of a triphasic BVF loaded with common antibiotics. BVF was mixed with vancomycin and/or tobramycin to form pellets, and the set time was recorded. A partial refreshment elution study was conducted with time points at 4, 8, and 24 h, as well as 2, 7, 14, 28, and 42 days. Effects on dissolution were evaluated in a 14-day dissolution study. Set time increased to over 1 h for groups containing tobramycin, although vancomycin had a minimal effect. Pellets continued to elute antibiotics throughout the 42-day elution study, suggesting efficacy for the treatment or prevention of orthopedic infections. BVF containing vancomycin or tobramycin showed similar dissolution at 14 days compared to BVF without antibiotics; however, BVF containing both antibiotics showed significantly more dissolution.

Calcium Phosphate Bone Void Filler Increases Threaded Suture Anchor Pullout Strength: A Biomechanical Study

2020 ◽  
Vol 36 (4) ◽  
pp. 1000-1008 ◽  
Author(s):  
Miguel A. Diaz ◽  
Eric A. Branch ◽  
Luis A. Paredes ◽  
Emily Oakley ◽  
Christopher E. Baker
Keyword(s):  
Calcium Phosphate ◽  
Suture Anchor ◽  
Biomechanical Study ◽  
Pullout Strength ◽  
Bone Void Filler ◽  
Bone Void

An Overview of the Percutaneous Antibiotic Delivery Technique for Osteomyelitis Treatment and a Case Study of Calcaneal Osteomyelitis

2017 ◽  
Vol 107 (6) ◽  
pp. 511-515 ◽  
Author(s):  
Jeffrey C. Karr
Keyword(s):  
Calcium Sulfate ◽  
Adjunctive Treatment ◽  
Case Presentation ◽  
Delivery Technique ◽  
Bone Void Filler ◽  
Bone Cortex ◽  
Bone Void ◽  
Carrier Vehicle ◽  
Antibiotic Delivery

Background:A percutaneous antibiotic delivery technique (PAD-T) used for the adjunctive management of osteomyelitis is presented.Methods:This surgical technique incorporates a calcium sulfate and hydroxyapatite (calcium phosphate) bone void filler acting as a carrier vehicle with either an antibiotic or an antifungal medicine, delivering this combination directly into the area of osteomyelitis.Results:The benefit of the PAD-T is reviewed with a case presentation of a successfully treated calcaneal osteomyelitis.Conclusions:No previously reported PAD-T using a simple bone cortex incision in the adjunctive treatment of osteomyelitis has been reported. The PAD-T safely and effectively uses a calcium sulfate and hydroxyapatite bone void filler carrier vehicle to deliver either an antibiotic or an antifungal medicine directly into the area of osteomyelitis.

A Rare Case of Chondroblastoma with Revision After Graft Rejection

2017 ◽  
Vol 107 (5) ◽  
pp. 440-445 ◽  
Author(s):  
Brandon Gumbiner ◽  
Elizabeth Jacobsen ◽  
Mary Stancukas ◽  
Ngan Nguyen
Keyword(s):  
Graft Rejection ◽  
Rare Case ◽  
Surgical Intervention ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Sinus Tract ◽  
Initial Surgery ◽  
Bone Void Filler ◽  
Calcaneal Cyst ◽  
Bone Void

We present a rare case of calcaneal chondroblastoma with subsequent surgical revision after graft rejection in a 13-year-old boy. Complications were encountered after the injectable bone graft filler was placed in the calcaneus after curettage. With noted subsequent sinus tract formation, revision surgery was performed that involved dissection of the sinus tract, removal of bone void filler, and application of demineralized bone matrix sponge human allograft soaked in vancomycin-impregnated saline. Sixteen weeks after the revision surgical intervention, the patient resumed normal athletic activities without pain or restrictions. One and a half years after the initial surgery, the patient had complete resolution of the calcaneal cyst and was discharged.

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