Small Blue Round Cell Tumor

2011 ◽  
Vol 101 (4) ◽  
pp. 363-369 ◽  
Author(s):  
J. Marshall Devall ◽  
Katherine M. Frush ◽  
Lori Steiner
Keyword(s):  
Genetic Testing ◽  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Definitive Diagnosis ◽  
Cell Tumor ◽  
Round Cell ◽  
Tissue Mass ◽  
Case Presentation ◽  
Poorly Differentiated ◽  
Round Cell Tumors

Small blue round cell tumors of childhood rarely present in the foot or ankle. The following is a case presentation of an 18-year-old male with a large soft-tissue mass of the foot with associated lung metastasis. A definitive diagnosis could not be fully made, even with immunohistochemical and genetic testing. Diagnosis favored poorly differentiated synovial sarcoma. (J Am Podiatr Med Assoc 101(4): 363–369, 2011)

Metastatic Prostate Cancer Presenting as Lower Extremity Soft Tissue Mass: A Rare Case Presentation

Urology ◽  
2017 ◽  
Vol 99 ◽  
pp. e27-e28
Author(s):  
Paulette Cutruzzula ◽  
Daniel C. Edwards ◽  
David Cahn ◽  
Carmen Tong ◽  
Dana Kivlin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Soft Tissue ◽  
Lower Extremity ◽  
Rare Case ◽  
Metastatic Prostate Cancer ◽  
Soft Tissue Mass ◽  
Tissue Mass ◽  
Case Presentation

Poorly Differentiated Chordomas Showing Loss of INI1/SMARCB1: A Report of 2 Rare Cases With Diagnostic Implications

2018 ◽  
Vol 26 (7) ◽  
pp. 637-643 ◽  
Author(s):  
Bharat Rekhi ◽  
Kemal Kosemehmetoglu ◽  
Swapnil Rane ◽  
Figen Soylemezoglu ◽  
Elif Bulut
Keyword(s):  
Soft Tissue ◽  
Tumor Cells ◽  
Soft Tissue Mass ◽  
Head Movements ◽  
Cervical Region ◽  
Tissue Mass ◽  
First Case ◽  
Radiologic Imaging ◽  
Poorly Differentiated ◽  
Mitotic Figures

Poorly differentiated chordomas are rare musculoskeletal tumors. Case 1. A 42-year-old lady presented with quadriparesis of 2 months’ duration. Radiologic imaging disclosed a soft tissue mass in her left prevertebral- and paravertebral cervical region. Case 2. A 4-year-old male child presented with neck pain and restricted head movements of 1-year duration. Radiologic imaging revealed a contrast enhancing, paraspinal soft tissue mass in his cervical region. Microscopic examination in both the cases revealed a cellular malignant tumor composed of moderate to markedly pleomorphic cells with interspersed mitotic figures, along with focal myxoid change and necrosis. By immunohistochemistry, tumor cells in both cases were diffusely positive for pan cytokeratin (AE1/AE3) and brachyury, whereas these were negative for INI1/SMARCB1. Tumor cells in the second case were also positive for glypican3. The first case developed pulmonary metastasis, while the second case developed recurrence. Poorly differentiated chordomas are uncommon tumors, invariably characterized by loss of INI1. These tumors can be rarely seen in adults and need to be differentiated from their diagnostic mimics, in view of treatment implications and their relatively aggressive clinical outcomes.

scholarly journals Lifethreatening tracheal obstruction in a child caused by nodular fasciitis: case presentation

2022 ◽  
Vol 16 (1) ◽  
Author(s):  
Yusuf Shieba ◽  
Mahmoud Khairy ◽  
Mohamed Elzouk ◽  
Albaraa Ali Mansour
Keyword(s):  
Soft Tissue ◽  
Early Detection ◽  
Airway Obstruction ◽  
Head And Neck ◽  
Soft Tissue Mass ◽  
Nodular Fasciitis ◽  
Tissue Mass ◽  
Case Presentation ◽  
Tracheal Obstruction ◽  
Life Threatening

Abstract Background Nodular fasciitis (NF) is a rare non-neoplastic inflammatory tumor and usually presents as a painless, rapidly growing subcutaneous soft tissue mass. The head and neck are relatively common locations for nodular fasciitis, particularly in children. NF in the trachea is rare and may evolve to a fatal condition, especially due to its rapidly growing nature that can cause life-threatening tracheal obstruction. Case presentation We report the case of a 5-year-old child with NF in the trachea and subtotal tracheal obstruction. Bronchoscopy and biopsy proved the diagnosis, and bronchoscopic excision of the tumor was performed. Conclusions NF is a rare airway tumor, occurring mostly in adults, and may presenting with pneumonia-like symptoms. Early detection of the lesion is essential to avoid life-threatening airway obstruction.

Schwannoma with Psammoma Body

2021 ◽  
Vol 111 (1) ◽  
Author(s):  
Lindsay M. Hummel ◽  
Susan Gamble ◽  
Robert Krouse ◽  
Darshana Jhala ◽  
Sharvari Dalal ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Carney Complex ◽  
Psammoma Body ◽  
Psammoma Bodies ◽  
Tissue Mass ◽  
Pathologic Evaluation ◽  
History Of ◽  
Male Veteran

We present a case of a 59-year-old male veteran with a chronic history of right foot soft-tissue mass that was causing pain in his shoes, but not functional or neurologic symptoms. Excision of the mass and pathologic evaluation resulted in multidisciplinary involvement and evaluation. In this example, the mass was found to be either an unusual schwannoma that happens to be psammoma body–rich or an unusual psammomatous melanocytic schwannoma that deviates from conventional examples, as a diagnostic consensus was unable to be reached. Schwannomas are an uncommon finding in the foot, and even more uncommon are those that contain psammoma bodies. Although rare, these tumors can be concerning for more systemic, life-altering diseases such as Carney complex, for which our patient refused genetic testing.

Recurrent Giant-Cell Tumor Presenting as a Soft-Tissue Mass. A Report of Four Cases*

1999 ◽  
Vol 81 (5) ◽  
pp. 703-7 ◽  
Author(s):  
FRANCIS YOUNG-IN LEE ◽  
MARK MONTGOMERY ◽  
ERIC J. HAZAN ◽  
SUZANNE B. KEEL ◽  
HENRY J. MANKIN ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Soft Tissue Mass ◽  
Cell Tumor ◽  
Tissue Mass ◽  
Recurrent Giant Cell Tumor

scholarly journals Pleomorphic Hyalinizing Angiectatic Tumor (PHAT): Review of the Literature with Case Presentation

2021 ◽  
Vol 8 (2) ◽  
pp. 97-102
Author(s):  
Gerardo Cazzato ◽  
Anna Colagrande ◽  
Antonietta Cimmino ◽  
Teresa Lettini ◽  
Maria Teresa Savino ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Subcutaneous Tissue ◽  
World Health ◽  
Tissue Mass ◽  
Case Presentation ◽  
Pleomorphic Hyalinizing Angiectatic Tumor ◽  
Health Organization ◽  
The Right ◽  
Upper Third

Pleomorphic hyalinizing angiectatic tumor (PHAT) is a very rare entity of soft tissue considered a “neoplasm of uncertain behaviour of connective or other soft tissue” by the World Health Organization (2020). It develops in subcutaneous tissue of the lower extremities, more frequently in the region of the ankle and foot, and rarely as a deep-seated soft tissue mass in locations such as the perineum, buttock, arms, head and neck, and viscera. Although inconsistent cytogenetic data have been reported on PHAT so far, there are potential morphological and genetic overlaps with hemosiderotic fibrolipomatous tumor (HFLT) and myxoinflammatory fibroblastic sarcoma (MIFS). Here we report a case of PHAT at the level of the upper third of the right thigh in a 48-year-old patient and we also focus on the differential diagnoses of these entities and conduct a literature review of reported cases.

scholarly journals Magnetic Resonance Imaging Features of Extradural Spinal Neoplasia in 60 Dogs and Seven Cats

2021 ◽  
Vol 7 ◽  
Author(s):  
Mylène Auger ◽  
Silke Hecht ◽  
Cary M. Springer
Keyword(s):  
Soft Tissue ◽  
Contrast Enhancement ◽  
Soft Tissue Mass ◽  
Differential Diagnoses ◽  
Benign Tumors ◽  
Imaging Features ◽  
Round Cell ◽  
Tissue Mass ◽  
Combined Features ◽  
Vertebral Shape

This retrospective study describes the MRI features of extradural spinal neoplasia in 60 dogs and seven cats to identify potential distinguishing features between tumor classes and individual tumor types within each class. In dogs, mesenchymal tumors were most common (48%), with undifferentiated sarcomas being the predominant tumor type. Round cell neoplasms were second most common (35%), with lymphoma and multiple myeloma/plasma cell tumor comprising the majority of cases. Only two benign tumors were identified. In cats, lymphoma was most common (5/7), with one case of mesenchymal neoplasia and one case of metastatic carcinoma. Despite some overlap, certain imaging features were able to help prioritize differential diagnoses. The combined features that predicted round cell neoplasia (84%) included the preservation of vertebral shape, homogeneous contrast enhancement, and lesion centering on bone. The combined features that predicted mesenchymal neoplasia (73%) included altered vertebral shape, heterogeneous contrast enhancement, and lesion centering on paraspinal soft tissues. Round cell neoplasms were more likely to have cortical sparing, preservation of overall shape, lesion centering on bone, small soft tissue tumor size, and homogeneous contrast enhancement. Both epithelial and mesenchymal neoplasms were more likely to have cortical lysis, a cavitary component to the soft tissue mass and medium to large soft tissue mass size. The findings of this study can aid in prioritizing differential diagnoses in cases of extradural spinal neoplasia in cats and dogs, which can impact case management, but tissue sampling remains the gold standard for definitive diagnosis.

Giant cell tumor with secondary aneurysmal bone cyst: A unique presentation with an ossified extraosseous soft tissue mass

2013 ◽  
Vol 42 (11) ◽  
pp. 1605-1610 ◽  
Author(s):  
Won Sun Hong ◽  
Mi Sook Sung ◽  
Jo-Heon Kim ◽  
Hyoung-Min Kim ◽  
Tae Kwan Kim ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Aneurysmal Bone Cyst ◽  
Soft Tissue Mass ◽  
Bone Cyst ◽  
Cell Tumor ◽  
Tissue Mass ◽  
Secondary Aneurysmal Bone Cyst

Soft tissue mass of the thigh: presentation

2007 ◽  
Vol 36 (12) ◽  
pp. 1177-1177 ◽  
Author(s):  
Tomoya Sakabe ◽  
Hiroaki Murata ◽  
Yukiko Tokumoto ◽  
Kazutaka Koto ◽  
Takaaki Matsui ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Tissue Mass
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