Current Assessment of Endovascular Therapy for Infrainguinal Arterial Occlusive Disease in Patients with Diabetes

2010 ◽  
Vol 100 (5) ◽  
pp. 424-428 ◽  
Author(s):  
Daniel M. Ihnat ◽  
Joseph L. Mills
Keyword(s):  
Endovascular Therapy ◽  
Limb Ischemia ◽  
Arterial Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Data Limitations ◽  
Patients With Diabetes ◽  
Current Assessment ◽  
Peripheral Arterial

Endovascular therapy has increasingly become the initial clinical option for the treatment of lower-extremity peripheral arterial occlusive disease not only for patients with claudication but also for those with critical limb ischemia. Despite this major clinical practice paradigm shift, the outcomes of endovascular therapy for peripheral arterial disease are difficult to evaluate and compare with established surgical benchmarks because of the lack of prospective randomized trials, incomplete characterization of indications for intervention, mixing of arterial segments and extent of disease treated, the multiplicity of endovascular therapy techniques used, the exclusion of early treatment failures, crossover to open bypass during follow-up, and the frequent lack of intermediate and long-term patency and limb salvage rates in life-table format. These data limitations are especially problematic when one tries to assess the outcomes of endovascular therapy in patients with diabetes. The purpose of the present article is to succinctly review and objectively analyze available data regarding the results of endovascular therapy in patients with diabetes. (J Am Podiatr Med Assoc 100(5): 424–428, 2010)

scholarly journals Clinical study of peripheral arterial occlusive disease of lower extremities

2018 ◽  
Vol 5 (4) ◽  
pp. 1388
Author(s):  
Prasad C. ◽  
Santosh Nayak K.
Keyword(s):  
Peripheral Arterial Disease ◽  
Peripheral Arterial Occlusive Disease ◽  
Lower Extremities ◽  
Limb Ischemia ◽  
Arterial Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Age Group ◽  
History Of ◽  
Peripheral Arterial

Background: Peripheral arterial occlusive disease or commonly known as peripheral arterial disease (PAD) comprises those entities which result in obstruction to blood flow in the arteries, exclusive of the coronary and intracranial vessels and the term is usually applied to disease involving the arteries of lower extremity. Peripheral arterial disease is an important manifestation of atherosclerosis involving the arteries of legs. Vascular surgeons continue to encounter complications of atherosclerosis as their most common clinical challenge. Objective of this study was to know the various etiologies and different clinical presentation of Peripheral arterial occlusive disease.Methods: This was a cross sectional observational study of 50 cases diagnosed with Peripheral Arterial disease of the lower extremities, done during the period from January 2013 to June 2014 among the Patients with Peripheral Arterial disease of the lower extremities admitted to surgical wards of SCBMCH, Cuttack.Results: All the cases in the present study fall under the category of chronic lower limb ischemia and no cases of acute limb ischemia. Majority of the cases in atherosclerosis were above the age of 50 years, while in the TAO group majority belong to the age group between 31 to 50 years. TAO was usually limited to the distal part of the limb. All patients with TAO had a history of smoking and 61% of atherosclerotic patients gave history of smoking.Conclusions: TAO and Atherosclerosis are the etiologies for ischemia in these cases, with atherosclerosis being more common of the two. TAO presented at a younger age group whereas atherosclerosis presented in the older age group.

scholarly journals Gender-related differences in critical limb ischemia due to peripheral arterial occlusive disease

2013 ◽  
Vol 12 (4) ◽  
pp. 278-283 ◽  
Author(s):  
Vanessa Prado dos Santos ◽  
Carlos Alberto Silveira Alves ◽  
Cicero Fidelis Lopes ◽  
Jose Siqueira de Araujo Filho
Keyword(s):  
Risk Factors ◽  
Critical Limb Ischemia ◽  
Peripheral Arterial Occlusive Disease ◽  
Clinical Characteristics ◽  
Limb Ischemia ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Male And Female ◽  
Female Patients ◽  
Peripheral Arterial

BACKGROUND: Mortality from cardiovascular disease has declined among men and increased among North American women. Recent studies have revealed differences between genders in the epidemiology of atherosclerotic disease. OBJECTIVE: To study possible differences between male and female patients with critical limb ischemia (CLI) according to risk factors of atherosclerosis and clinical characteristics of lower limbs with peripheral arterial occlusive disease (PAOD). METHODS: The study included 171 male and female patients treated for CLI due to infrainguinal PAOD and compared clinical characteristics (Rutherford category and PAOD territory), risk factors for atherosclerosis (diabetes, age, smoking and hypertension) and number of opacified arteries on digital angiograms of the leg. The EPI-INFO software was used for statistical analysis, and the level of significance was set at p<0.05. RESULTS: Mean age was 70 years, and 88 patients were men (52%). For most patients (both genders), Rutherford category was 5 (82 % of men and 70% of women; p=0.16). The group of women had higher mean age (73 vs. 67 years; p=0.0002) and greater prevalence of diabetes (66% vs. 45%; p=0.003) and hypertension (90% vs. 56%; p=0.0000001). Among men, the prevalence of smoking was higher (76% vs. 53%; p=0.0008). The analysis of digital angiograms revealed that opacification of only one artery in the leg was found for 74% of women (vs. 50% of men). CONCLUSION: The prevalence of risk factors for atherosclerosis and the characteristics of PAOD are different between male and female patients with CLI.

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