From the modern viewpoint and by the geometric method, this paper provides a concise foundation for the quantum theory of massless spin-3/2 field in Minkowski spacetime, which includes both the one-particle's quantum mechanics and the many-particle's quantum field theory. The explicit result presented here is useful for the investigation of spin-3/2 field in various circumstances such as supergravity, twistor programme, Casimir effect, and quantum inequality.