scholarly journals IN-VITRO ANTHELMINTIC ACTIVITY OF AERIAL ROOTS OF FICUS BENGHALENSIS

2011 ◽  
Vol 1 (1) ◽  
Author(s):  
Trupti Tuse ◽  
A.A. Bidkar ◽  
S.A. Bhale ◽  
R.D. Patankar
Keyword(s):  
Anthelmintic Activity ◽  
Ficus Benghalensis ◽  
Aerial Roots

scholarly journals INVESTIGATION OF PHARMACOGNOSTICAL, PHYTOCHEMICAL, AND PHARMACOLOGICAL ACTIVITY OF AERIAL ROOTS OF FICUS BENGHALENSIS LINN

2018 ◽  
Vol 11 (10) ◽  
pp. 279
Author(s):  
Kamalika Mazumder ◽  
Himangshu S Maji ◽  
Nripendra N Bala
Keyword(s):  
Antioxidant Activity ◽  
Ethyl Acetate ◽  
Analgesic Activity ◽  
Ethyl Acetate Extract ◽  
Microscopic Investigation ◽  
Tail Flick ◽  
Ficus Benghalensis ◽  
Aerial Roots

Objective: Ficus benghalensis Linn. (Moraceae family) is commonly known as banyan tree in English, which is used traditionally in India. The literature survey showed that the aerial roots of this plant are yet to be explored. Our main interest is to evaluate its pharmacognostic and phytochemical character by the standard monograph and to explore its in vitro antioxidant and in vivo analgesic activity study with ethyl acetate extract.Methods: Pharmacognostic evaluation and phytochemical screening have been done using standard monograph. An in vitro antioxidant activity using ethyl acetate extract has been done using four different methods. In vivo analgesic activity of the ethyl acetate extract has been evaluated by acetic acid-induced writhing test in mice and tail flick method.Results: Aerial roots of F. benghalensis have been found the rich source of steroidal glycosides, cardiac glycosides, flavonoids, tri-terpenoids, and phenols. The presence of phellem, phellogen, xylem, and phloem has been found after microscopic investigation. All the pharmacognostic parameters proved its purity. Results showed the absence of heavy metals. The ethyl acetate extract has shown potent antioxidant activity at 100 μg/ml concentration and higher analgesic activity at the concentration of 400 mg/kg than 200 mg/kg.Conclusion: Pharmacognostic characteristics and phytochemical properties revealed in this study could be used for the pharmacopoeial standard. Ethyl acetate extract showed potent antioxidant and analgesic activity.

scholarly journals Formulation and Evaluation of Ficus Benghalensis Emulgel for its Anti- Rheumatoid Arthritis Effect

2021 ◽  
pp. 31-36
Author(s):  
Sonali ◽  
Mohd. Aqil Siddiqui ◽  
Amresh Gupta ◽  
Arpita Singh ◽  
Nitish Kumar
Keyword(s):  
Petroleum Ether Extract ◽  
Ethanolic Extract ◽  
Moisture Loss ◽  
Ficus Benghalensis ◽  
Aerial Roots ◽  
Carbopol 940 ◽  
First Pass ◽  
Release Method

The current study focuses on the development and characterization of ficus benghalensis powdered aerial roots emulgel to avoid the first-pass effect and strengthen bioavailability while reducing dosage intervals and dose-related deleterious reactions. three formulations with the same concentration and different polymers were formulated. Ethanolic and petroleum ether extract of dried aerial roots of ficus benghalensis were prepared by using different gelling agents like  Carbopol 934, Carbopol 940, and Xanthane gum was formulated. The prepared formulations were evaluated for their qualitative as well as quantitative tests, physical appearance, pH, viscosity, spreadability, consistency, homogeneity, moisture loss, and finally in vitro anti-arthritic activity. Depending on the outcomes, it was observed that to all the formulation, F1 formulation containing Carbopol 940 with 4.6% moisture loss, 3780.3±5.0 viscosity and 6.1±0.1 PH and 43.7±1.53 spreadability shows better activity then all the other. Herbal emulgel of ethanolic extract of dried aerial roots of ficus benghalensis line, when compared with diclofenac emulgel, confirms the anti-arthritic activity through invitro release method.

scholarly journals Use of Aerial Roots of Ficus benghalensis for Green Synthesis of Silver Nanoparticles with Enhanced Antibacterial Activity

2021 ◽  
pp. 257-267
Author(s):  
Tarannum Rashid Patave ◽  
Aquil-Ur Rahim Siddiqui
Keyword(s):  
Staphylococcus Aureus ◽  
Silver Nanoparticles ◽  
High Resolution ◽  
High Speed ◽  
Bacterial Infections ◽  
Research Work ◽  
Silver Ions ◽  
Ficus Benghalensis ◽  
Aerial Roots

Basically, nanosubstances are developed by a variety of chemical methods which are not environmentally providential. Aim: The present research work deals with the synthesis of silver nanoparticles using the aerial root of Ficus benghalensis extract. The absolute reduction of silver ions was observed after 48 h of reaction when extact combine with aqueous solution of Silver nitrate. The visual colour changes were observed during the reduction of silver ion into the silver nanoparticles in the reaction mixture allows producing dark brown colour. The formed silver nanoparticles was purified by high speed centrifugation, collected and stored for further characterization. Methodology: The formation of silver nanoparticles was confirmed by UV-Visible spectroscopy, and characterised by X-Ray Diffraction (XRD) pattern, FTIR, High Resolution Transmission Electron Microscopy (HRTEM), Zeta potentiometry, ICP-AES. Results: The results showed that UV peak at 437.5 nm, the silver content estimation by ICP-AES was found to be 413.06 µg/mL and images were recorded by using High resolution TEM. Synthesized AgNPs were found to be effective against micro-organisms responsible for bacterial infections like Staphylococcus aureus, Pseudomonas aeruginosa, E. coli and Methicillin resistant Staphylococcus Aureus (MRSA). Further In-vitro cytocompatibility studies showed lack of toxicity at even higher concentration.  Conclusion: Still, these Silver Nanoparticles are cytotoxic in nature and could serve as a good green method for synthesis of silver nanoparticle by using plant extract. 

In vitro anthelmintic activity of Pimienta dioica and Origanum vulgare essential oils on gastrointestinal nematodes from sheep and cattle

2021 ◽  
Author(s):  
Gerardo Jiménez-Penago ◽  
Roberto González-Garduño ◽  
Luciano Martínez-Bolaños ◽  
Ema Maldonado-Siman ◽  
Alvar A. Cruz-Tamayo ◽  
...  
Keyword(s):  
Essential Oils ◽  
Anthelmintic Activity ◽  
Gastrointestinal Nematodes ◽  
Origanum Vulgare

Chemical characterization and in vitro anthelmintic activity of Citrus bergamia Risso and Citrus X paradisii Macfad essential oil against Haemonchus contortus Kirby isolate

Acta Tropica ◽  
2021 ◽  
Vol 217 ◽  
pp. 105869
Author(s):  
Vivien Patricia Garbin ◽  
Beatriz Munguía ◽  
Jenny Carolina Saldaña ◽  
Cícero Deschamps ◽  
Roger Raupp Cipriano ◽  
...  
Keyword(s):  
Essential Oil ◽  
Haemonchus Contortus ◽  
Chemical Characterization ◽  
Anthelmintic Activity ◽  
Citrus Bergamia

In vitro anthelmintic activity of Dennettia tripetala G. Baker (Annonaceae) Fruits against Haemonchus contortus

2021 ◽  
Author(s):  
Rachel A. Nwosu ◽  
Mohammed M. Suleiman ◽  
Hussaina J. Makun ◽  
Matthew P. Ameh ◽  
Manji A. Shetshak ◽  
...  
Keyword(s):  
Haemonchus Contortus ◽  
Anthelmintic Activity ◽  
Dennettia Tripetala

In Vitro Nematocidal Effect and Anthelmintic Activity of Artemisia cina Against Haemonchus contortus in Gerbils and Relative Expression of Hc29 Gene in Transitional Larvae (L3–L4)

2021 ◽  
Author(s):  
Rosa Isabel Higuera-Piedrahita ◽  
Mariana Dolores-Hernández ◽  
Luis Gerardo Jiménez-Pérez ◽  
Brígida C. Camacho-Enríquez ◽  
Alejandro Zamilpa ◽  
...  
Keyword(s):  
Haemonchus Contortus ◽  
Anthelmintic Activity ◽  
Relative Expression

Anthelmintic activity in vitro of Citrus sinensis and Melaleuca quinquenervia essential oil from Cuba on Haemonchus contortus

2015 ◽  
Vol 76 ◽  
pp. 647-652 ◽  
Author(s):  
Yousmel Aleman Gaínza ◽  
Luciana Ferreira Domingues ◽  
Oriela Pino Perez ◽  
Márcio Dias Rabelo ◽  
Eugenio Roque López ◽  
...  
Keyword(s):  
Essential Oil ◽  
Haemonchus Contortus ◽  
Citrus Sinensis ◽  
Anthelmintic Activity ◽  
Melaleuca Quinquenervia

scholarly journals The effects of flubendazole and its metabolites on the larval development of Haemonchus contortus (Nematoda: Trichostrongylidae): an in vitro study

2010 ◽  
Vol 47 (4) ◽  
pp. 269-272 ◽  
Author(s):  
H. Bártíková ◽  
L. Skálová ◽  
J. Lamka ◽  
B. Szotáková ◽  
M. Várady
Keyword(s):  
Larval Development ◽  
Haemonchus Contortus ◽  
Anthelmintic Activity ◽  
In Vitro Study ◽  
Lethal Concentration ◽  
Resistant Isolate ◽  
Susceptible Isolate ◽  
Marked Resistance ◽  
Larval Development Test

AbstractThe anthelmintic effects of flubendazole (FLU), its two main metabolites reduced flubendazole (FLU-R) and hydrolyzed flubendazole (FLU-H), and thiabendazole (TBZ) were compared using an in vitro larval development test in two isolates of Haemonchus contortus, a fully susceptible isolate (HCS) and a multi-resistant isolate (HCR). Results were quantified as 50 % lethal concentration (LC50), 99 % lethal concentration (LC99), efficacy factor (EF), and resistance factor (RF). For HCS, both LC50 and LC99 of FLU were lower than those of the reference TBZ. The anthelmintic activity of FLU-R in HCS and HCR was 13 and 6 times lower than the activity of FLU, respectively. The anthelmintic activity of FLU-H was negligible (approximately 363–853 times lower) compared to that of FLU. Although a marked resistance of the HCR isolate to TBZ was confirmed, only a low tolerance to FLU-R and slightly higher tolerance to FLU were found.

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME NEWER BENZIMIDAZOLE DERIVATIVES BY MANNICH REACTION

INDIAN DRUGS ◽  
2019 ◽  
Vol 56 (07) ◽  
pp. 16-22
Author(s):  
N. Kumar ◽  
D Pathak ◽  
Keyword(s):  
Salicylic Acid ◽  
Elemental Analysis ◽  
Mannich Reaction ◽  
Anthelmintic Activity ◽  
Biological Evaluation ◽  
Benzimidazole Derivatives ◽  
Good Activity ◽  
Mass Spectral Data ◽  
Mass Spectral

O-phenylenediamine and salicylic acid were used for the synthesis of 2-(1-(substituted phenylamino) methyl-1H benzo[d] imidazol-2-yl) phenol (2a-2h) derivatives by using various substituted aniline. In the first step, reaction of o-phenylenediamine and salicylic acid yielded 2-(1H-benzo[d]imidazol-2-yl) phenol (1), which on Mannich reaction with substituted aniline gave compounds (2a-2h). The structures of these compounds were characterized by IR, 1H NMR, mass spectral data and elemental analysis. Each analogue was tested in vitro for various types of pharmacological activity of this class of drugs including antibacterial, antifungal and anthelmintic activity. Among the synthesized compounds 2a act as vermifuge and no compound was found to be a vermicide. The compound 2c was found to be most active against E.coli and P. aeurigenosa and 2e be most active against B.subtilis and S.aureus. The derivative 2h shows good activity against C.albicans and A.niger.

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