THE USE OF RESPONSE SURFACE METHODOLOGY IN OPTIMIZATION PROCESS FOR BACTERIOCIN PRODUCTION

2011 ◽  
Vol 2 (11) ◽  
Author(s):  
Arokiyamary A. ◽  
Sivakumaar P.K.
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Bacteriocin Production ◽  
Optimization Process

Application of Response Surface Methodology in the Optimization of Magneto-Hydrodynamic Flow Around and Through a Porous Circular Cylinder

2018 ◽  
Vol 34 (5) ◽  
pp. 695-710 ◽  
Author(s):  
S. M. Vahedi ◽  
A. Zare Ghadi ◽  
M. S. Valipour
Keyword(s):  
Response Surface Methodology ◽  
Nusselt Number ◽  
Drag Coefficient ◽  
Response Surface ◽  
Mhd Flow ◽  
Reynolds Numbers ◽  
Darcy Number ◽  
Optimization Process ◽  
Staggered Grid ◽  
Polar Coordinate

AbstractIn this study MHD flow around and through porous cylinder is numerically investigated. The governing equations are developed in polar coordinate arrangement in both porous and non-porous media on the basis of single-domain technique. The equations are solved numerically based on finite volume method over staggered grid structure. Nusselt number and drag coefficient are selected as two key parameters describing performance of this system. By applying response surface methodology the sensitivity of these parameters to main factors of the problem, including Stuart number, Darcy number and Reynolds number are quantified. RSM is also utilized to perform an optimization process to find the best condition in which the lowest drag force and highest heat transfer rate occur simultaneously. The CFD analysis is carried out for variant Reynolds numbers (10 ≤ Re ≤ 40), Darcy numbers (10-6 ≤ Da ≤ 10-2) and Stuart numbers (2 ≤ N ≤ 10). Streamlines and isotherms are presented to indicate the impacts of such parameters on heat and fluid flow. It can be seen that, Drag coefficient and Nusselt number increase by augmenting magnetic field strength. Beside, Darcy number and Reynolds numbers have a direct and inverse effect on Nuave and Cd, respectively. Results of optimization process show that Nuave and Cd are more sensitive to Reynolds and Stuart numbers, respectively, while they less sensitive to Darcy number. Moreover, it is revealed that the optimum condition occurs at Da = 10-2, Re = 38.1 and N = 4.49.

scholarly journals Enzymatic Phorbol Esters Degradation using the Germinated Jatropha Curcas Seed Lipase as Biocatalyst: Optimization Process Conditions by Response Surface Methodology

2016 ◽  
Vol 11 (3) ◽  
pp. 346 ◽  
Author(s):  
Avita Kusuma Wardhani ◽  
Chusnul Hidayat ◽  
Pudji Hastuti
Keyword(s):  
Response Surface Methodology ◽  
Reaction Time ◽  
Response Surface ◽  
Jatropha Curcas ◽  
Phorbol Esters ◽  
Optimization Process ◽  
Process Conditions ◽  
Seed Cake ◽  
Heat Stable ◽  
Jatropha Seeds

<p>Utilization of Jatropha curcas seed cake is limited by the presence of phorbol esters (PE), which are the main toxic compound and heat stable. The objective of this research was to optimize the reaction conditions of the enzymatic PE degradation of the defatted Jatropha curcas seed cake (DJSC) using the acetone-dried lipase from the germinated Jatropha curcas seeds as a biocatalyst. Response Surface Methodology (RSM) using three-factors-three-levels Box-Behnken design was used to evaluate the effects of the reaction time, the ratio of buffer volume to DJSC, and the ratio of enzyme to DJSC on PE degradation. The results showed that the optimum conditions of PE degradation were 29.33 h, 51.11 : 6 (mL/g), and 30.10 : 5 (U/g cake) for the reaction time, the ratio of buffer volume to DJSC, and the ratio of enzyme to DJSC, respectively. The predicted degradation of PE was 98.96% and not significantly different with the validated data of PE degradation. PE content was 0.035 mg/g, in which it was lower than PE in non-toxic Jatropha seeds. The results indicated that enzymatic degradation of PE might be a promising method for degradation of PE.  Copyright © 2016 BCREC GROUP. All rights reserved</p><p><em>Received: 22<sup>nd</sup> December 2015; Revised: 1<sup>st</sup> April 2016; Accepted: 14<sup>th</sup> April 2016</em></p><p><strong>How to Cite:</strong> Wardhani, A.K., Hidayat, C., Hastuti, P. (2016). Enzymatic Phorbol Esters Degradation using the Germinated Jatropha Curcas Seed Lipase as Biocatalyst: Optimization Process Conditions by Response Surface Methodology. <em>Bulletin of Chemical Reaction Engineering &amp; Catalysis</em>, 11 (3): 346-353 (doi:10.9767/bcrec.11.3.574.346-353)</p><p><strong>Permalink/DOI:</strong> <a href="http://doi.org/10.9767/bcrec.11.3.574.346-353">http://doi.org/10.9767/bcrec.11.3.574.346-353</a></p>

UV/H2O2 Process for Removal of Total Organic Carbon from Refinery Effluent: Screening of Influence Factors Using Response Surface Methodology

2014 ◽  
Vol 917 ◽  
pp. 168-177 ◽  
Author(s):  
Sabtanti Harimurti ◽  
Anisa Ur Rahmah ◽  
Abdul Aziz Omar ◽  
Thanapalan Murugesan
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Influence Factors ◽  
Process Condition ◽  
Degradation Process ◽  
Optimization Process ◽  
Fenton Reagent ◽  
High Concentration ◽  
Refinery Effluent ◽  
Wide Range

Effluent containing high concentration of alkanolamine from a sweetening process of natural gas plant is commonly generated during maintaining, cleaning and scheduled inspection of the absorption and desorption column. The effluent is not readily biodegradable and cannot be treated in the conventional biological treatment. Advanced oxidation processes (AOPs) is a promising method for the treatment of recalcitrant organic contaminant. Most methods used are Fenton reagent, UV/Ozone and UV/H2O2. Based on the advantages of the UV/H2O2such as no formation of sludge during the treatment, high ability in production of hydroxyl radical and applicable in the wide range of pH, the UV/H2O2has been chosen to treat the effluent from refinery plant, which has high concentration of methyldietnaolamine (MDEA). The factors influencing in the degradation of refinery wastewater that contain MDEA were screened using response surface methodology (RSM). It was found that degradation process of the refinery effluent was highly dependent on oxidant concentration (H2O2) and initial pH. Temperature of oxidation process was found oppositely. Since the temperature gave insignificant effect on the TOC removal process, hence the independent factor temperature will be eliminated during the further optimization process condition of degradation. Thus, the optimization process condition of degradation will be more effective and simpler.

scholarly journals Trans-Esterification Optimization Process for Biodiesel Production from Palm Kernel Oil using Response Surface Methodology

2021 ◽  
Vol 6 (2) ◽  
pp. 7-15
Author(s):  
T.O. Rabiu ◽  
N.A. Folami ◽  
N.A. Badiru ◽  
N.A. Kinghsley ◽  
B.T. Dare ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Reaction Time ◽  
Sodium Hydroxide ◽  
Response Surface ◽  
Catalyst Concentration ◽  
Palm Kernel ◽  
Biodiesel Production ◽  
Optimization Process ◽  
Palm Kernel Oil ◽  
Kernel Oil

The ever-growing concern for the safety of lives and the environment as well as the depletion in fossil fuels reserves across the globe has led to the keen interests of many researchers in the field of renewable energy. This study was therefore undertaken to investigate the trans-esterification optimization process for biodiesel production from palm kernel using response surface methodology. The materials for the trans-esterification processes were palm kernel oil, Methanol and sodium hydroxide. The effects of reaction temperature (oC), catalyst concentration (wt%) and reaction time (min) on the yield were evaluated. The properties of the biodiesel produced showed that it met the ASTM standard for biodiesel. A quadratic polynomial model, Yield (%) = 78.60–3.12A–.62B + 0.00C -0.75AB – 3.50AC + 1.50BC + 2.82A2– 0.18B2 + 1.08C2, was developed that can be used to predict yield of biodiesel at any value of the different parameters investigated. The ANOVA for the model of the biodiesel yield obtained indicates that the models fit well in describing the relationship between the predictor (biodiesel yield) and the factors (methanol to oil ratio, catalyst concentration and reaction time). The optimal trans-esterification conditions were found to be 60°C for temperature, 60minutes for reaction time, 0.878w% of oil as Sodium hydroxide (catalyst) concentration and methanol/oil ratio of 1:6. At these optimal conditions, the biodiesel yield was fond to be 89.32% The generated biodiesel had high cetane number, better engine ignitability and poses lesser pollution problems than petroleum diesel.

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