Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke

2018 ◽  
Vol 168 (5) ◽  
pp. 335 ◽  
Author(s):  
Rahman Shah ◽  
Mannu Nayyar ◽  
Ion S. Jovin ◽  
Abdul Rashid ◽  
Beatrix R. Bondy ◽  
...  
2020 ◽  
Vol 22 (Supplement_M) ◽  
pp. M43-M50
Author(s):  
Iris Parrini ◽  
Enrico Cecchi ◽  
Davide Forno ◽  
Alexander R Lyon ◽  
Riccardo Asteggiano

Abstract Patent foramen ovale (PFO) and cryptogenic stroke (CS) both have a high prevalence. The optimal treatment to reduce stroke recurrence after CS remains controversial. Results from clinical trials, meta-analyses, and position papers, support percutaneous PFO device closure and medical therapy compared to medical therapy alone. However, the procedure may be associated with cardiac complications including an increased incidence of new atrial fibrillation. The benefit/risk balance should be determined on a case-by-case basis with the greatest benefit of PFO closure in patients with atrial septal aneurysm and PFO with large shunts. Future studies should address unsolved questions such as the choice of medical therapy in patients not undergoing closure, the duration of antiplatelet therapy, and the role of PFO closure in patients over 60 years old.


2013 ◽  
Vol 6 (12) ◽  
pp. 1316-1323 ◽  
Author(s):  
Abdur R. Khan ◽  
Aref A. Bin Abdulhak ◽  
Mujeeb A. Sheikh ◽  
Sobia Khan ◽  
Patricia J. Erwin ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document