Routine Iron Supplementation and Screening for Iron Deficiency Anemia in Pregnancy: A Systematic Review for the U.S. Preventive Services Task Force

2015 ◽  
Vol 162 (8) ◽  
pp. 566 ◽  
Author(s):  
Amy G. Cantor ◽  
Christina Bougatsos ◽  
Tracy Dana ◽  
Ian Blazina ◽  
Marian McDonagh
Keyword(s):  
Systematic Review ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
Task Force ◽  
Preventive Services ◽  
Deficiency Anemia ◽  
Anemia In Pregnancy ◽  
The U.S ◽  
In Pregnancy

Treatment of Iron Deficiency Anemia in Pregnancy with Intravenous versus Oral Iron: Systematic Review and Meta-Analysis

2018 ◽  
Vol 36 (04) ◽  
pp. 366-376 ◽  
Author(s):  
Richard Burwick ◽  
Shravya Govindappagari
Keyword(s):  
Systematic Review ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Meta Analysis ◽  
Oral Iron ◽  
Sensitivity Analyses ◽  
Deficiency Anemia ◽  
Iv Iron ◽  
Anemia In Pregnancy ◽  
In Pregnancy

Objective To perform a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the benefits of intravenous (IV) iron in pregnancy. Study Design Systematic review was registered with PROSPERO and performed using PRISMA guidelines. PubMed, MEDLINE, Web of Science, ClinicalTrials.gov, Cochrane Library, and Google Scholar were searched. Eleven RCTs, comparing IV to oral iron for treatment of iron-deficiency anemia in pregnancy, were included. Meta-analyses were performed with Stata software (College Station, TX), utilizing random effects model and method of DerSimonian and Laird. Outcomes were assessed by pooled odds ratios (OR) or pooled weighted mean difference (WMD). Sensitivity analyses were performed for heterogeneity. Results We found that pregnant women receiving IV iron, compared with oral iron, had the following benefits: (1) Achieved target hemoglobin more often, pooled OR 2.66 (95% confidence interval [CI]: 1.71–4.15), p < 0.001; (2) Increased hemoglobin level after 4 weeks, pooled WMD 0.84 g/dL (95% CI: 0.59–1.09), p < 0.001; (3) Decreased adverse reactions, pooled OR 0.35 (95% CI: 0.18–0.67), p = 0.001. Results were unchanged following sensitivity analyses. Conclusion In this meta-analysis, IV iron is superior to oral iron for treatment of iron-deficiency anemia in pregnancy. Women receiving IV iron more often achieve desired hemoglobin targets, faster and with fewer side effects.

scholarly journals Iron deficiency anemia in pregnancy: controversies in iron supplementation

2015 ◽  
Vol 48 (4) ◽  
pp. 401
Author(s):  
Maria Teresa C. F. Modott ◽  
Cauê C. Modott ◽  
Mônica Y. Marcelino ◽  
Taís B. de Oliva ◽  
Daniel S. Dias ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
Deficiency Anemia ◽  
Anemia In Pregnancy ◽  
In Pregnancy

O período gestacional está associado a uma série de alterações fisiológicas e anatômicas, tais como mudanças no sistema hematológico, respiratório e cardiovascular. Além das alterações funcionais, a anemia por deficiência de ferro (anemia ferropriva) destaca-se como uma das complicações mais comuns de uma gravidez e dependendo da gravidade, pode acarretar prejuízo para mãe e/ou feto. A administração de ferro para as gestantes, com ou sem diagnóstico prévio de anemia, é uma prática comum na área de obstetrícia. Embora não existam evidências concretas a respeito dos beneficios da suplementa- ção profilática de ferro para as gestantes, esta conduta apresenta-se como um procedimento adequado, visto que reduz a prevalência de anemia ferropriva na gestante e após o parto. Entretanto, há uma série de relatos na literatura que descrevem os aspectos deletérios da reposição indiscriminada de ferro durante a gestação. Neste contexto, pretende-se com essa revisão da literatura apresentar os principais aspectos das alterações hematológicas decorrentes da gravidez, em especial a anemia por deficiência de ferro, mostrar as ventagens e desvantagens da suplementação com ferro, bem como orientar o obstetra em realizar um diagnóstico mais preciso de anemia ferropriva durante a gestação e propor uma alternativa coerente de reposição de ferro para as gestantes, minimizando os riscos indesejáveis do excesso ou deficiência dessa suplementação.

Intravenous compared with oral iron for the treatment of iron-deficiency anemia in pregnancy: a systematic review and meta-analysis

2019 ◽  
Vol 39 (4) ◽  
pp. 519-532 ◽  
Author(s):  
Adam K. Lewkowitz ◽  
Anjlie Gupta ◽  
Laura Simon ◽  
Bethany A. Sabol ◽  
Carrie Stoll ◽  
...  
Keyword(s):  
Systematic Review ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Meta Analysis ◽  
Oral Iron ◽  
Deficiency Anemia ◽  
Anemia In Pregnancy ◽  
In Pregnancy

scholarly journals Three-Month Iron Supplementation as Treatment for Microcytic Hypochromic Anemia in Pregnancy

2021 ◽  
Vol 53 (2) ◽  
Author(s):  
Donel Donel ◽  
Dhini Aiyulie Novri ◽  
Ruza Prima Rustam ◽  
Maya Savira
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
Hypochromic Anemia ◽  
Primary Data ◽  
Deficiency Anemia ◽  
Quasi Experimental ◽  
Anemia In Pregnancy ◽  
In Pregnancy

In pregnant women there is a twofold increase in iron requirements due to increased blood volume without the expansion of plasma volume. Pregnant women are very prone to suffering from iron deficiency anemia. Iron deficiency anemia generally has an erythrocyte index which represents hypochromic microcytic. This study aimed to determine the effect of three-month iron tablet supplementation as a therapy against microcytic hypochromic anemia in pregnancy. This was a quantitative quasi-experimental study using pre-test and post-test design. The study was conducted in May-September 2020 at the Arifin Achmad Regional General Hospital, Riau Province, Indonesia. Subjects were 30 pregnant women with microcytic hypochromic anemia. Primary data were analyzed using statistical paired sample t-tests. Results showed that there was an increase in hemoglobin levels after the supplementation of iron tablet from an average of 9.1 ± 1.2 gr/dl to 11.8 ± 1.0 g/dl. This change was significant based on the results of the T-test (p-0.003) Thus, iron supplementation for three month significantly increases hemoglobin levels in pregnant women.

Sign in / Sign up

Export Citation Format

Share Document