scholarly journals Drug Utilization Evaluation of Anticancer Drugs in a Tertiary Care Teaching Hospital: a Descriptive Observational Study

Author(s):  
Vinodkumar Mugada ◽  
Aswinichand Paruchuri ◽  
Mounika Munagala
Author(s):  
Sunil Kardani ◽  
Rajesh Hadia ◽  
Jay Patel ◽  
Jeel Patel ◽  
Trupal Rathod ◽  
...  

Background: Antiepileptic drugs (AEDs) are the mainstay of the therapy for epilepsy, despite the development in recent years of new therapeutic options, such as brain stimulation or Surgery. Objective: To understand the pattern of drug utilization and medication adherence of anti-epileptic drugs (AEDs) among epileptic patients at a tertiary care teaching hospital. Methodology: A cross-sectional observational study of a total of 120 subjects receiving anti-epileptics was done. All the patients with epilepsy were prescribed with anti-epileptic drug who visited, admitted, or referred to the Department of Neurology. All inpatients and outpatients of epilepsy were screened for the study. Results: A total of 120 patients were included in our study into which (38.33%) were inpatients and (61.67%) were outpatient. The male (56%) patients were more as compared to female (44%) patients. A maximum number of patients were from the age group of 21-40 (41%) year. The majority of the patient were suffered from focal epilepsy (63%), remaining were having a generalized seizure. The highest comorbidities were found to be HTN and diabetes mellitus. Monotherapy was highly prescribed as compare to polytherapy. Among single AED, the maximum prescribed drug was Carbamazepine [30% (N=17)] followed by 25% (N=14) of phenytoin and levetiracetam 21% (N=12). In two AED Combinations, the most prescribed drugs were clobazam + Levetiracetam and Midazolam + phenytoin 12% (N=5) followed by sodium valproate + clobazam 10% (N=4). Highest combination of three AEDs that were prescribed the highest were carbamazepine + Levetiracetam + clobazam and phenytoin + phenobarbitone + sodium Valproate 20% (N=2) The highest medication adherence was found in patients who were on single AEDs and the lowest adherence was found in the patients who were on more than two AEDs. Conclusion: Antiepileptic drug monotherapy was highly prescribed as compare to polytherapy. Phenytoin was the most commonly prescribed AEDs followed by carbamazepine and highly prescribed single AEDs were found to be carbamazepine. The patients who were on single epileptic drugs showed the highest adherence as compared to the patients with more than two AEDs.


2021 ◽  
Vol 23 (11) ◽  
pp. 930-950
Author(s):  
Dr Baharul Islam H ◽  
◽  
Dr Amirhossein Abedini ◽  
Dr Suvijin C ◽  
Dr Shinad AV ◽  
...  

INTRODUCTION: A study on antihypertensive usage in a tertiary care teaching hospital necessary to realize that drugs inappropriate use represents a potential hazard to the patient and unnecessary expenses. This necessitates a periodic review of the pattern of drug utilization to ensure safe and effective treatment. The ultimate goal is to focus on the factors related to the prescribing, dispensing, administering and taking medication. AIM: To analyse the drug utilization evaluation of antihypertensives in a tertiary care teaching hospital. METHODOLOGY: A prospective, observational and analytical study was carried out for six months from November 2019 to April 2020 in the inpatient from different departments of a tertiary care teaching hospital in Mysore district with the aim of drug utilization evaluation antihypertensives. RESULT: A total of 332 patients were taken into the study. 32% (103) of the patient were in the age group of 41-50 years, and this was found to be higher in a male population, 57%. During the study, 51.6% of the patients were stage 1 hypertension, followed by prehypertension and stage 2 hypertension. The most common class of drugs prescribed in the study was ACE inhibitors, 31.1%, followed by CCB 21.4%, and the most prescribed medication in the study were captopril 21.7% and nifedipine 14.3%. Diabetes mellitus was the most common comorbid condition, 35.7% associated with hypertension, followed by hyperthyroidism 14.5%. CONCLUSION: This study concluded that by providing insight into the prescription pattern of antihypertensive medication concerning various comorbidities control, it helps the prescriber pay more attention to specific factors that affect the outcome of various comorbidities.


2016 ◽  
Vol 9 (4) ◽  
pp. 231-235
Author(s):  
Vijeesh Tholur Subrahmanian ◽  
Kannan Gopal ◽  
Murugan Sundaram ◽  
Purnima Ashok ◽  
Satya Sai Minnikanti Venkata

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