scholarly journals Antimicrobial activities of mycoleptodiscin B isolated from endophytic fungus Mycoleptodiscus sp. of Calamus thwaitesii Becc.

2016 ◽  
pp. 001-006 ◽  
Author(s):  
Ranga Dissanayake ◽  
Pamoda Ratnaweera ◽  
David Williams ◽  
C. Wijayarathne ◽  
Ravi Wijesundera ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Antimicrobial Activities ◽  
Calamus Thwaitesii

Chemistry and weak antimicrobial activities of phomopsins produced by mangrove endophytic fungus Phomopsis sp. ZSU-H76

2008 ◽  
Vol 69 (7) ◽  
pp. 1604-1608 ◽  
Author(s):  
Zhongjing Huang ◽  
Xiaoling Cai ◽  
Changlun Shao ◽  
Zhigang She ◽  
Xuekui Xia ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Antimicrobial Activities ◽  
Mangrove Endophytic Fungus

Lactones from a Brown Alga Endophytic Fungus (No. ZZF36) from the South China Sea and Their Antimicrobial Activities.

ChemInform ◽  
2006 ◽  
Vol 37 (51) ◽  
Author(s):  
Rui-yun Yang ◽  
Chun-yuan Li ◽  
Yong-cheng Lin ◽  
Guang-tian Peng ◽  
Zhi-gang She ◽  
...  
Keyword(s):  
South China Sea ◽  
South China ◽  
Endophytic Fungus ◽  
Brown Alga ◽  
Antimicrobial Activities ◽  
The South China Sea ◽  
The South ◽  
China Sea

A new fusicoccane diterpene and a new polyene from the plant endophytic fungus Talaromyces pinophilus and their antimicrobial activities

2019 ◽  
Vol 35 (1) ◽  
pp. 124-130 ◽  
Author(s):  
Wen-Ting Zhao ◽  
Xiong Shi ◽  
Peng-Jie Xian ◽  
Zhang Feng ◽  
Jian Yang ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Antimicrobial Activities ◽  
Talaromyces Pinophilus

Two new glycosidal metabolites of endophytic fungus Penicillium sp. (NO.4) from Tapiscia sinensis

2016 ◽  
Vol 71 (4) ◽  
pp. 283-286 ◽  
Author(s):  
Qiao Wan ◽  
Ziwei Feng ◽  
Xueshuang Li ◽  
Mengmeng Lv ◽  
Zhiyong Guo ◽  
...  
Keyword(s):  
Methyl Ester ◽  
Cell Lines ◽  
Cancer Cell ◽  
Endophytic Fungus ◽  
Cancer Cell Line ◽  
2D Nmr ◽  
Cancer Cell Lines ◽  
Antimicrobial Activities ◽  
Cytotoxic Activities ◽  
A549 Cancer Cell Line

AbstractTwo new glycosides, 8-O-β-d-glucopyranosyl-6-methyl-1-carboxylate methyl ester xanthone (1) and 4′-O-β-d-galactopyranosyl djalonensone (2), together with four known compounds, 8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate methyl ester (3), cassionllin (4), djalonensone (5) and alternariol (6), were isolated from the endophytic fungus Penicillium sp. (NO.4) of Tapiscia sinensis Oliv. The structures of compounds 1–6 were elucidated by the analysis of 1D and 2D NMR and HRMS. The cytotoxic activities of these compounds were evaluated against four cancer cell lines, as well as antimicrobial activities against two plant-pathogenic microbes. Compounds 1–6 showed moderate cytotoxicity against the A549 cancer cell line with IC50 values ranging from 6.8 to 35.8 μg mL−1 and were found to be inactive against three other cancer cell lines MCF-7, Caski and Hep G-2.

scholarly journals Prenylated Diphenyl Ethers from the Marine Algal-Derived Endophytic Fungus Aspergillus tennesseensis

Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2368 ◽  
Author(s):  
Zhao-Xia Li ◽  
Xiu-Fang Wang ◽  
Guang-Wei Ren ◽  
Xiao-Long Yuan ◽  
Ning Deng ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Diphenyl Ether ◽  
Antimicrobial Activities ◽  
Cytotoxic Activities ◽  
Ic50 Value ◽  
Diphenyl Ethers ◽  
Marine Algal ◽  
Spectroscopy Studies ◽  
New Compounds

Considerable attention has been paid to marine derived endophytic fungi, owing to their capacity to produce novel secondary metabolites with potent bioactivities. In this study, two new compounds with a prenylated diphenyl ether structure—diorcinol L (1) and (R)-diorcinol B (2)—were isolated from the marine algal-derived endophytic fungus Aspergillus tennesseensis, along with seven known compounds: (S)-diorcinol B (3), 9-acetyldiorcinol B (4), diorcinol C (5), diorcinol D (6), diorcinol E (7), diorcinol J (8), and a dihydrobenzofuran derivative 9. Their structures were elucidated by extensive NMR spectroscopy studies. Compound 2 represents the first example of an R-configuration in the prenylated moiety. All these isolated compounds were examined for antimicrobial and cytotoxic activities. Compounds 1–9 exhibited antimicrobial activities against some human- and plant-pathogenic microbes with MIC values ranging from 2 to 64 μg/mL. Moreover, compound 9 displayed considerable inhibitory activity against the THP-1 cell line in vitro, with an IC50 value of 7.0 μg/mL.

ChemInform Abstract: Chemistry and Weak Antimicrobial Activities of Phomopsins Produced by Mangrove Endophytic Fungus Phomopsis sp. ZSU-H76.

ChemInform ◽  
2008 ◽  
Vol 39 (41) ◽  
Author(s):  
Zhongjing Huang ◽  
Xiaoling Cai ◽  
Changlun Shao ◽  
Zhigang She ◽  
Xuekui Xia ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Antimicrobial Activities ◽  
Mangrove Endophytic Fungus

scholarly journals Antimicrobial Meroterpenoids and Erythritol Derivatives Isolated from the Marine-Algal-Derived Endophytic Fungus Penicillium chrysogenum XNM-12

Marine Drugs ◽  
2020 ◽  
Vol 18 (11) ◽  
pp. 578
Author(s):  
Kuo Xu ◽  
Xu-Lun Wei ◽  
Lin Xue ◽  
Zhong-Feng Zhang ◽  
Peng Zhang
Keyword(s):  
Plant Pathogen ◽  
Endophytic Fungus ◽  
Penicillium Chrysogenum ◽  
2D Nmr ◽  
Antimicrobial Activities ◽  
Penicillium Species ◽  
Pyrone Ring ◽  
Planar Structures ◽  
Marine Algal ◽  
Optical Rotations

One new meroterpenoid-type alkaloid, oxalicine C (1), and two new erythritol derivatives, penicierythritols A (6) and B (7), together with four known meroterpenoids (2–5), were isolated from the marine algal-derived endophytic fungus Penicillium chrysogenum XNM-12. Their planar structures were determined by means of spectroscopic analyses, including UV, 1D and 2D NMR, and HRESIMS spectra. Their stereochemical configurations were established by comparing the experimental and calculated electronic circular dichroism (ECD) spectra for compound 1, as well as by comparison of the optical rotations with literature data for compounds 6 and 7. Notably, oxalicine C (1) represents the first example of an oxalicine alkaloid with a cleaved α-pyrone ring, whereas penicierythritols A (6) and B (7) are the first reported from the Penicillium species. The antimicrobial activities of compounds 1–7 were evaluated. Compounds 1 and 6 exhibited moderate antibacterial effects against the plant pathogen Ralstonia solanacearum with minimum inhibitory concentration (MIC) values of 8 and 4 μg/mL, respectively. Compound 6 also possesses moderate antifungal properties against the plant pathogen Alternaria alternata with a MIC value of 8 μg/mL.

scholarly journals Perylene Derivatives Produced by Alternaria alternata, an Endophytic Fungus Isolated from Laurencia Species

2009 ◽  
Vol 4 (11) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Shu-Shan Gao ◽  
Xiao-Ming Li ◽  
Bin-Gui Wang
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Aspergillus Niger ◽  
Alternaria Alternata ◽  
Endophytic Fungus ◽  
Spectroscopic Analysis ◽  
Algal Species ◽  
Antimicrobial Activities ◽  
Perylene Derivatives

Two new perylene derivatives, 7-epi-8-hydroxyaltertoxin I (1) and 6-epi-stemphytriol (2), along with two known compounds stemphyperylenol (3) and altertoxin I (4) were isolated from Alternaria alternata, a marine endophytic fungus derived from an unidentified algal species of the genus Laurencia. Structures of compounds 1-4 were determined on the basis of detailed spectroscopic analysis, as well as by comparison with literature reports. The antimicrobial activities of compounds 1 and 3 against Staphylococcus aureus, Escherichia coli, and Aspergillus niger were evaluated; neither showed obvious activity.

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