scholarly journals Comparison of antifungal activity of medicinal plant Tylophora indica Merr. with its in vitro raised plant and callus

2012 ◽  
Vol 7 (9) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Mini Dhiman ◽  
Rajashri R. Parab ◽  
Sreedharannair L. Manju ◽  
Dattatraya C. Desai ◽  
Girish B. Mahajan

The antimicrobial efficacy of two phenanthroindolizidine alkaloids, tylophorinidine hydrochloride (TdnH) and tylophorinine hydrochloride (TnnH), isolated from the plant Tylophora indica (local name, Antamul) was evaluated. These were screened for in vitro antifungal and antibacterial activities. Both compounds exhibited potent antifungal activity displaying minimum inhibitory concentrations (MIC) in the range of 2-4 μg/mL for TdnH and 0.6-2.5 μg/mL for TnnH against Candida species.


2005 ◽  
Vol 40 (1-2) ◽  
pp. 43-54 ◽  
Author(s):  
K. Yamunarani ◽  
R. Jaganathan ◽  
R. Bhaskaran ◽  
P. Govindaraju ◽  
R. Velazhahan

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