scholarly journals Chaotic global parameters correlation with heart rate variability in obese children

2014 ◽  
Vol 24 (1) ◽  
pp. 24 ◽  
Author(s):  
Franciele M. Vanderlei ◽  
Luiz Carlos M. Vanderlei ◽  
David M. Garner

The aim of the study is to analyze heart rate dynamics in obese children by measures of HRV. HRV is a simple and non-invasive measure of autonomic impulses. 94 children of mixed gender aged eight to twelve years were divided into two equal groups based on body mass index: obese and normal weight range. HRV was monitored in the dorsal decubitus position for 20 minutes. After tests of normality, Kruskal Wallis was applied for the statistical analysis, with the level of significance set at (p < 0.05). Regarding the application of Principal Component Analysis the first two components represent 99.4% of total variance. The obese children exhibited in heart frequency dynamics associated to an increase in the Chaos Forward Parameter. The Chaos Forward Parameter which applies all three chaotic global parameters is suggested to be the most robust algorithm. Obesity in children can be termed a dynamical condition but it increases the chaotic response.

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Aline Fernanda Barbosa Bernardo ◽  
Luiz Carlos M. Vanderlei ◽  
David M. Garner

This study’s aim is to analyze heart rate dynamics in subjects with chronic obstructive pulmonary disease (COPD) by measures of heart rate variability (HRV). HRV is a simple and noninvasive measure of autonomic impulses. 38 adults were divided into two equal groups based on respiratory function: COPD and normal. HRV was monitored in the supine position for 30 minutes. After tests of normality, Kruskal-Wallis was used for the statistical analysis, with the level of significance set at P<0.05. Principal component analysis identified two components representing 99.5% of total variance. Furthermore, it is suggested that the chaos forward parameter (CFP) which applies all three “chaotic globals” is the most influential, although others are statistically more significant. The COPD subjects exhibited a decrease in the CFP. COPD can be termed a dynamical condition, decreasing the chaotic response. The perceived benefits of such analysis include quantitative assessment and suitable pharmacological intervention in the respiratory condition, especially of other related dynamical diseases such as cardiac failure.


2012 ◽  
Vol 12 (04) ◽  
pp. 1240017 ◽  
Author(s):  
SUMEET DUA ◽  
XIAN DU ◽  
S. VINITHA SREE ◽  
THAJUDIN AHAMED V. I.

Coronary artery disease (CAD) is a leading cause of death worldwide. Heart rate variability (HRV) has been proven to be a non-invasive marker of the autonomic modulation of the heart. Nonlinear analyses of HRV signals have shown that the HRV is reduced significantly in patients with CAD. Therefore, in this work, we extracted nonlinear features from the HRV signals using the following techniques: recurrence plots (RP), Poincare plots, and detrended fluctuation analysis (DFA). We also extracted three types of entropy, namely, Shannon entropy (ShanEn), approximation entropy (ApEn), and sample entropy (SampEn). These features were subjected to principal component analysis (PCA). The significant principal components were evaluated using eight classification techniques, and the performances of these techniques were evaluated to determine which presented the highest accuracy in classifying normal and CAD classes. We observed that the multilayer perceptron (MLP) method resulted in the highest classification accuracy (89.5%) using our proposed technique.


Fractals ◽  
2009 ◽  
Vol 17 (04) ◽  
pp. 385-394 ◽  
Author(s):  
AKIHIKO KIKUCHI ◽  
NOBUYA UNNO

Multifractal analysis has recently been validaded as an excellent method by which to analyze heart rate variability and in distinguishing healthy subjects from patients with various types of the cardiac nervous system dysfunction. Our objective was to improve the understanding of the multifractal properties of fetal heart rate (FHR) variability in healthy normal fetuses according to gestational age, and to determine whether the heart rate dynamics in growth-restricted fetuses is different from normal fetuses by multifractal analysis. One hundred nineteen FHR recordings obtained from healthy normal fetuses and 68 recordings obtained from small-for-gestational-age (SGA) fetuses were analyzed to examine gestational and pathologic changes of the degree of multifractality. A significant decrease was observed in the degree of multifractality of healthy normal fetuses according to gestational age. The degree of multifractality of SGA fetuses was significantly higher than that of healthy normal fetuses. Moreover, the degree of multifractality of complicated SGA fetuses who ultimately showed nonreassuring FHR patterns was significantly higher than that of uncomplicated SGA fetuses. And the latter was significantly higher than that of healthy normal fetuses. The degree of multifractality appears to be a sensitive probe for detecting subtle, and possibly important, changes that occur in fetuses with intrauterine growth restriction (IUGR), and may be helpful in the early and non-invasive detection of placental insufficiency or incipient IUGR. The mechanisms underlying FHR regulation in IUGR fetuses seem to be different from those of cardiac pathology in adults.


2009 ◽  
Vol 12 (1) ◽  
pp. E10-E16 ◽  
Author(s):  
Jus Ksela ◽  
Piotr Suwalski ◽  
Jurij Matija Kalisnik ◽  
Viktor Avbelj ◽  
Grzegorz Suwalski ◽  
...  

2020 ◽  
Vol 16 (1) ◽  
pp. 47-53
Author(s):  
Vicente Benavides-Córdoba ◽  
Mauricio Palacios Gómez

Introduction: Animal models have been used to understand the pathophysiology of pulmonary hypertension, to describe the mechanisms of action and to evaluate promising active ingredients. The monocrotaline-induced pulmonary hypertension model is the most used animal model. In this model, invasive and non-invasive hemodynamic variables that resemble human measurements have been used. Aim: To define if non-invasive variables can predict hemodynamic measures in the monocrotaline-induced pulmonary hypertension model. Materials and Methods: Twenty 6-week old male Wistar rats weighing between 250-300g from the bioterium of the Universidad del Valle (Cali - Colombia) were used in order to establish that the relationships between invasive and non-invasive variables are sustained in different conditions (healthy, hypertrophy and treated). The animals were organized into three groups, a control group who was given 0.9% saline solution subcutaneously (sc), a group with pulmonary hypertension induced with a single subcutaneous dose of Monocrotaline 30 mg/kg, and a group with pulmonary hypertension with 30 mg/kg of monocrotaline treated with Sildenafil. Right ventricle ejection fraction, heart rate, right ventricle systolic pressure and the extent of hypertrophy were measured. The functional relation between any two variables was evaluated by the Pearson correlation coefficient. Results: It was found that all correlations were statistically significant (p <0.01). The strongest correlation was the inverse one between the RVEF and the Fulton index (r = -0.82). The Fulton index also had a strong correlation with the RVSP (r = 0.79). The Pearson correlation coefficient between the RVEF and the RVSP was -0.81, meaning that the higher the systolic pressure in the right ventricle, the lower the ejection fraction value. Heart rate was significantly correlated to the other three variables studied, although with relatively low correlation. Conclusion: The correlations obtained in this study indicate that the parameters evaluated in the research related to experimental pulmonary hypertension correlate adequately and that the measurements that are currently made are adequate and consistent with each other, that is, they have good predictive capacity.


1992 ◽  
Vol 19 (3) ◽  
pp. 453-459 ◽  
Author(s):  
Alan Garfinkel ◽  
Sheryl L. Raetz ◽  
Ronald M. Harper

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Elisa Mejía-Mejía ◽  
James M. May ◽  
Mohamed Elgendi ◽  
Panayiotis A. Kyriacou

AbstractHeart rate variability (HRV) utilizes the electrocardiogram (ECG) and has been widely studied as a non-invasive indicator of cardiac autonomic activity. Pulse rate variability (PRV) utilizes photoplethysmography (PPG) and recently has been used as a surrogate for HRV. Several studies have found that PRV is not entirely valid as an estimation of HRV and that several physiological factors, including the pulse transit time (PTT) and blood pressure (BP) changes, may affect PRV differently than HRV. This study aimed to assess the relationship between PRV and HRV under different BP states: hypotension, normotension, and hypertension. Using the MIMIC III database, 5 min segments of PPG and ECG signals were used to extract PRV and HRV, respectively. Several time-domain, frequency-domain, and nonlinear indices were obtained from these signals. Bland–Altman analysis, correlation analysis, and Friedman rank sum tests were used to compare HRV and PRV in each state, and PRV and HRV indices were compared among BP states using Kruskal–Wallis tests. The findings indicated that there were differences between PRV and HRV, especially in short-term and nonlinear indices, and although PRV and HRV were altered in a similar manner when there was a change in BP, PRV seemed to be more sensitive to these changes.


2021 ◽  
Vol 73 (1) ◽  
Author(s):  
Juraj Jug ◽  
Lada Bradić ◽  
Rea Levicki ◽  
Martina Lovrić Benčić

Abstract Background Syncope, as the most frequent consciousness disorder, is very common in young individuals. The aim of this study was to analyze ECG parameters and clinical properties obtained during tilt-up testing in 12 to 30-year-old subjects. We enrolled a total of 142 patients from our outpatient clinic (39 males, 103 females) with a true positive tilt-up test and analyzed ECG records obtained during tilt-testing. Data were stratified according to the age, gender, and type of syncope. Results PR interval shortening preceding syncope was found in all syncope types, irrespective of the gender. All types of syncope were more frequent in women (72.5%). Mixed syncope type was found to be the most common (47.18%). Male and female subjects differed in initial heart rate (71.56 vs 76.23/min, p=0.05), as well as heart rate dynamics during tilt-up testing. A gender difference was also found in systolic blood pressure (116.92 vs 110.44 mmHg, p<0.01), time to syncope onset (20.77 vs. 16.44 min, p=0.03), and the total number of syncopal episodes in patient history (2.79 vs. 4.62, p<0.05). Subjects with cardioinhibitory syncope had the longest PR interval (average 154.3 ms). PR interval prolongation and loss of variability during tilt-up testing positively correlated with aging (r=0.22, p<0.05). Nodal rhythm was found in 8 patients. Conclusion PR interval shortening on ECG tracings during a tilt-up test can be found in all subtypes of vasovagal syncope, thereby contrasting previous reports that these changes are a hallmark of the cardioinhibitory type of syncope. PR shortening, if observed during ECG monitoring, could be a potential predictor of syncope.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Alberto Sánchez ◽  
José Tuñón ◽  
Manuel Montejo ◽  
Pilar Amate ◽  
Bautista Ceprián ◽  
...  

AbstractThis paper discusses results obtained from in situ analysis of the tesserae of the Roman mosaic of Los Amores (Cástulo site, Linares, Spain) dating back to the turn of the 1st to the 2nd century AD. Specifically, it focuses on the scene The Judgment of Paris. In view of the exceptional state of preservation of the mosaic, from which very few tesserae had fallen off, non-invasive methods with portable Micro Raman Spectroscopy (MRS) and hand-held X-ray fluorescence (hXRF) and data assessment by use of principal component analysis and binary representations were selected. The results obtained allow to evaluate both the analytical method and the portable equipment used, as well as to classify the raw materials, the colouring agents and the opacifiers used. MRS analysis proved crucial for the identification of stone tesserae (ironstones, carbonate and siliciclastic rocks) and for the identification of the type of glasses used (soda-lime-silicate and lead type glasses) based on the analysis of two detached tesserae. hXRF analysis of the glass tesserae identified both colouring agents (Co, Cu, Pb, Zn) and opacifiers (calcium antimonate). The data obtained lend themselves to an assessment of the degradation process that threaten the integrity of the mosaic. The identification of tessera made of specific stone materials (especially ironstone) and of lead glass tesserae suggest the existence of a mosaic workshop in the Upper Guadalquivir (Eastern Andalusia, Spain).


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ky Young Cho

Abstract Background The association between the gut microbiota and pediatric obesity was analyzed in a cross-sectional study. A prospective study of obese children was conducted to assess the gut microbial alterations after a weight change. We collected fecal samples from obese children before and after a 2-month weight reduction program that consisted of individual counseling for nutritional education and physical activity, and we performed 16S rRNA gene amplicon sequencing using an Illumina MiSeq platform. Results Thirty-six participants, aged 7 to 18 years, were classified into the fat loss (n = 17) and the fat gain (n = 19) groups according to the change in total body fat (%) after the intervention. The baseline analysis of the gut microbiota in the preintervention stages showed dysbiotic features of both groups compared with those of normal-weight children. In the fat loss group, significantly decreased proportions of Bacteroidetes phylum, Bacteroidia class, Bacteroidales order, Bacteroidaceae family, and Bacteroides genus, along with increased proportions of Firmicutes phylum, Clostridia class, and Clostridiales order, were observed after intervention. The microbial richness was significantly reduced, without a change in beta diversity in the fat loss group. The fat gain group showed significantly deceased proportions of Firmicutes phylum, Clostridia class, Clostridiales order, Lachnospiraceae family, and Eubacterium hallii group genus, without a change in diversity after the intervention. According to the functional metabolic analysis by the Phylogenetic Investigation of Communities by Reconstruction of Unobserved States 2, the “Nitrate Reduction VI” and “Aspartate Superpathway” pathways were predicted to increase significantly in the fat loss group. The cooccurring networks of genera were constructed and showed the different microbes that drove the changes between the pre- and postintervention stages in the fat loss and fat gain groups. Conclusions This study demonstrated that lifestyle modifications can impact the composition, richness, and predicted functional profiles of the gut microbiota in obese children after weight changes. Trial registration ClinicalTrials.govNCT03812497, registration date January 23, 2019, retrospectively registered.


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