scholarly journals The Australian science gateways ecosystem

2016 ◽  
Author(s):  
Michelle Barker
Keyword(s):  
Research Collaboration ◽  
Research Community ◽  
Endocrine Disorders ◽  
Australian Government ◽  
Software Infrastructure ◽  
Data Movement ◽  
Research Software ◽  
Science Gateways ◽  
Virtual Laboratories ◽  
Successes And Challenges

This talk examines Australian government initiatives to facilitate the development of science gateways, and identifies the successes and challenges in this approach. Since 2011 the Australian Government has funded the development of science gateways through the National eResearch Collaborative Tools and Resources ( NeCTAR ) program (www.nectar.org.au). NeCTAR has funded the development of twelve science gateways in diverse disciplines that provide highly collaborative, research-domain oriented, integrative research software infrastructure to meet researcher-defined needs. The virtual laboratories enable over 10,000 users to access data, models, analytical and workflow tools through a single online platform. NeCTAR also funds the Research Cloud , which provides computing infrastructure, software and services to enable Australia’s research community to store, access, and run data, remotely, rapidly and autonomously. NeCTAR Cloud’s self-service structure allows over 7,500 users to access their own data at any time and collaborate with others from their desktop in a fast and efficient way. NeCTAR aims to enhance research collaboration through the development of eResearch infrastructure. This paper explores the structure of the NeCTAR Virtual Laboratory program, its successes and challenges, and future plans. Key features of the program include creation of platforms where tools, models and data meeting, enabling automating and sharing of research methodologies and democratisation of access. As such, the Virtual Laboratories deliver transformative research impacts and are exemplars for sector adoption of capability. Virtual Laboratories exist in disciplines including climate and weather science, genomics, characterisation, biodiversity and climate change, astronomy, human communication science, marine studies, geophysics, endocrine disorders, and cultural studies. Some of the enabling factors include governance structures that emphasise ownership of the Virtual Laboratories by the research community, strong user engagement in development and a support program that assists in enabling issues across the Virtual Laboratories. This has run project in areas such as provenance, authentication, security, data movement and user support. Challenges exist in sustaining a strategic approach to research software infrastructure, particularly strengthening the focus on shared research software services, improving research software quality, reliability and sustainability, and building capability within the research communities. This paper will also provide opportunities for comparison and identification of potential alignment with other national/regional/disciplinary programs. Europe and USA have both initiated funding programs that have some similarities to the NeCTAR Virtual Laboratories program; however, these also take some different approaches on some issues.

scholarly journals The Australian science gateways ecosystem

2016 ◽  
Author(s):  
Michelle Barker
Keyword(s):  
Research Collaboration ◽  
Research Community ◽  
Endocrine Disorders ◽  
Australian Government ◽  
Software Infrastructure ◽  
Data Movement ◽  
Research Software ◽  
Science Gateways ◽  
Virtual Laboratories ◽  
Successes And Challenges

This talk examines Australian government initiatives to facilitate the development of science gateways, and identifies the successes and challenges in this approach. Since 2011 the Australian Government has funded the development of science gateways through the National eResearch Collaborative Tools and Resources ( NeCTAR ) program (www.nectar.org.au). NeCTAR has funded the development of twelve science gateways in diverse disciplines that provide highly collaborative, research-domain oriented, integrative research software infrastructure to meet researcher-defined needs. The virtual laboratories enable over 10,000 users to access data, models, analytical and workflow tools through a single online platform. NeCTAR also funds the Research Cloud , which provides computing infrastructure, software and services to enable Australia’s research community to store, access, and run data, remotely, rapidly and autonomously. NeCTAR Cloud’s self-service structure allows over 7,500 users to access their own data at any time and collaborate with others from their desktop in a fast and efficient way. NeCTAR aims to enhance research collaboration through the development of eResearch infrastructure. This paper explores the structure of the NeCTAR Virtual Laboratory program, its successes and challenges, and future plans. Key features of the program include creation of platforms where tools, models and data meeting, enabling automating and sharing of research methodologies and democratisation of access. As such, the Virtual Laboratories deliver transformative research impacts and are exemplars for sector adoption of capability. Virtual Laboratories exist in disciplines including climate and weather science, genomics, characterisation, biodiversity and climate change, astronomy, human communication science, marine studies, geophysics, endocrine disorders, and cultural studies. Some of the enabling factors include governance structures that emphasise ownership of the Virtual Laboratories by the research community, strong user engagement in development and a support program that assists in enabling issues across the Virtual Laboratories. This has run project in areas such as provenance, authentication, security, data movement and user support. Challenges exist in sustaining a strategic approach to research software infrastructure, particularly strengthening the focus on shared research software services, improving research software quality, reliability and sustainability, and building capability within the research communities. This paper will also provide opportunities for comparison and identification of potential alignment with other national/regional/disciplinary programs. Europe and USA have both initiated funding programs that have some similarities to the NeCTAR Virtual Laboratories program; however, these also take some different approaches on some issues.

scholarly journals The ABCs of Collaboration in Academia

2019 ◽  
Vol 24 (2) ◽  
pp. 39-53
Author(s):  
Diana Amundsen ◽  
Nadine Ballam ◽  
Marg Cosgriff
Keyword(s):  
Lived Experiences ◽  
Research Collaboration ◽  
Academic Research ◽  
Research Community ◽  
Community Research ◽  
Research Partnerships

The occurrence of research collaboration among multiple researchers is becoming more widespread within the academic research community. Research collaboration endeavours offer many benefits yet are not without challenges. This think piece draws on our lived experiences as educators and university researchers to evaluate a research collaboration journey. The process prompted us to deeply question and critically reflect on what enables and supports research collaboration in academic research partnerships. We undertook a critical reflective-in-action study collecting and analysing data for a period of 15 months. We uncovered three elements we propose are integral to supporting effective research collaboration practice and outcomes in academia. These are Acknowledging the Affective, Becoming Bolder, and Cultivating Creativity in what we term, the ‘ABCs of collaboration in academia.

scholarly journals Pediatric Cancer Data Commons: Federating and Democratizing Data for Childhood Cancer Research

2021 ◽  
pp. 1034-1043
Author(s):  
Alejandro Plana ◽  
Brian Furner ◽  
Monica Palese ◽  
Nicole Dussault ◽  
Suzi Birz ◽  
...  
Keyword(s):  
Pediatric Oncology ◽  
Pediatric Cancer ◽  
Research Collaboration ◽  
The United States ◽  
Research Community ◽  
Essential Information ◽  
Cancer Data ◽  
Large Patient ◽  
Patient Consent ◽  
Data Commons

The international pediatric oncology community has a long history of research collaboration. In the United States, the 2019 launch of the Children's Cancer Data Initiative puts the focus on developing a rich and robust data ecosystem for pediatric oncology. In this spirit, we present here our experience in constructing the Pediatric Cancer Data Commons (PCDC) to highlight the significance of this effort in fighting pediatric cancer and improving outcomes and to provide essential information to those creating resources in other disease areas. The University of Chicago's PCDC team has worked with the international research community since 2015 to build data commons for children's cancers. We identified six critical features of successful data commons design and implementation: (1) establish the need for a data commons, (2) develop and deploy the technical infrastructure, (3) establish and implement governance, (4) make the data commons platform easy and intuitive for researchers, (5) socialize the data commons and create working knowledge and expertise in the research community, and (6) plan for longevity and sustainability. Data commons are critical to conducting research on large patient cohorts that will ultimately lead to improved outcomes for children with cancer. There is value in connecting high-quality clinical and phenotype data to external sources of data such as genomic, proteomics, and imaging data. Next steps for the PCDC include creating an informed and invested data-sharing culture, developing sustainable methods of data collection and sharing, standardizing genetic biomarker reporting, incorporating radiologic and molecular analysis data, and building models for electronic patient consent. The methods and processes described here can be extended to any clinical area and provide a blueprint for others wishing to develop similar resources.

scholarly journals An evidence base to optimise methods for involving patient and public contributors in clinical trials: a mixed-methods study

2015 ◽  
Vol 3 (39) ◽  
pp. 1-142 ◽  
Author(s):  
Carrol Gamble ◽  
Louise Dudley ◽  
Alison Allam ◽  
Philip Bell ◽  
Deborah Buck ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Mixed Methods ◽  
Public Involvement ◽  
Research Collaboration ◽  
Research Programme ◽  
Evidence Base ◽  
Research Community ◽  
Future Research ◽  
Randomised Trials ◽  
Managerial Roles

BackgroundIn comparison with other study designs, randomised trials are regarded as particularly likely to benefit from patient and public involvement (PPI). Using mixed-methods research we investigated PPI from the perspectives of researchers and PPI contributors.MethodsRandomised trials in receipt of funding from the Health Technology Assessment (HTA) programme between 2006 and 2010 were identified. Funding applications and board and referee comments were obtained and data relevant to PPI extracted. Chief investigators (CIs), PPI contributors and UK Clinical Research Collaboration Registered Clinical Trials Units (RCTUs) were surveyed. Interviews were conducted with researchers and PPI contributors.ResultsA total of 111 trials were included. Text relevant to PPI was identified in half of the trials for which the first-stage applications were available, but only one-quarter described PPI within their development. In the second stage of the application, the majority provided some text relevant to PPI, with over half having PPI in their development. Fewer than half of referees commented on PPI, and funding boards rarely provided comments in relation to PPI. Seventy-three per cent (81 of 111) of CIs responded to the survey and 98% (79 of 81) included PPI at some stage in their trial. CIs considered high impact from PPI contributors to occur more frequently in trial setup, with low or no impact being more common during trial conduct, analysis and dissemination. Only one-third of CIs provided PPI contributor contact details but all contributors contacted completed the survey. The majority of contributors felt engaged and valued by the research team. Interviews were conducted with researchers and/or PPI contributors for 28 trials identifying two main influences on perception of PPI impact: whether or not CIs expressed personal goals and plans for PPI; and the quality of their relationship with the PPI contributors. The importance of early engagement was identified, with opportunity for input thereafter limited. Three PPI roles were identified: oversight, managerial and responsive. Oversight roles, as required by funders, were associated with low impact in comparison with responsive or managerial roles. Most researchers could see some value in PPI training for researchers, although those that had received such training themselves expressed concerns about its purpose and evidence base. Training for PPI contributors was considered unnecessary, with conversational approaches preferred, although this did not appear to provide an opportunity for role negotiation. The RCTU survey response rate was 85% (39 of 46). The majority (37 of 39) reported PPI within trials co-ordinated by their unit. Trial characteristics were used by half to determine the approach to PPI. Two-thirds reported recent developments or changes in implementing plans for PPI (21 of 33). Support to PPI contributors was commonly offered through members of staff at the unit.ConclusionsPPI is occurring in the majority of trials funded by the HTA programme, but uncertainty remains about how it is assessed and valued. Early involvement, building a relationship between researchers and contributors, responsive or managerial roles, and having defined goals for PPI were associated with impact. Efficiency could be gained by utilising the RCTU network to identify and tackle challenges, and develop a risk-based approach utilising trial characteristics. Recommendations are made to trial funders and the research community. Given the difficulties for some informants in recalling PPI contributions, future research using a prospective approach would be valuable. Ethnographic research that combines observation and multi-informant interviews is likely to be informative in identifying impact. The research community needs to give further consideration to processes for selecting PPI contributors and models of implementing PPI.FundingThe National Institute for Health Research Health Services and Delivery Research programme and INVOLVE.

scholarly journals Supply Chain Innovation in Scientific Research Collaboration

2019 ◽  
Vol 11 (3) ◽  
pp. 753 ◽  
Author(s):  
Chih-Hung Yuan ◽  
Yenchun Wu ◽  
Kune-muh Tsai
Keyword(s):  
United States ◽  
Supply Chain ◽  
Research Collaboration ◽  
The United States ◽  
Research Community ◽  
Future Research ◽  
Collaborative Network ◽  
Collaboration Networks ◽  
Research Papers ◽  
The United Kingdom

Innovations in supply chains and logistics, which help businesses reduce their costs and meet customer needs, have become increasingly vital. In this study, we first conducted a content analysis followed by a social network analysis to systematically review 104 research papers on supply chain innovation (SCI) that were published between 1987 and 2018. The results suggest that SCI research was originally concentrated in the United States and did not receive much attention in Europe and Asia, until more recently. An analysis of collaboration networks indicates that an SCI research community has just started to form, with the United Kingdom at the center of the international collaborative network. Implications of the study and directions for future research are summarized in detail, based on the systematic literature review.

scholarly journals Deletion Mutants, Archived Transposon Library, and Tagged Protein Constructs of the Model Sulfate-Reducing Bacterium Desulfovibrio vulgaris Hildenborough

2021 ◽  
Vol 10 (11) ◽  
Author(s):  
Judy D. Wall ◽  
Grant M. Zane ◽  
Thomas R. Juba ◽  
Jennifer V. Kuehl ◽  
Jayashree Ray ◽  
...  
Keyword(s):  
Research Collaboration ◽  
Research Community ◽  
Desulfovibrio Vulgaris ◽  
Deletion Mutants ◽  
Content Type ◽  
Sulfate Reducing ◽  
Desulfovibrio Vulgaris Hildenborough ◽  
Genetic Constructs ◽  
Protein Constructs

ABSTRACT The dissimilatory sulfate-reducing deltaproteobacterium Desulfovibrio vulgaris Hildenborough (ATCC 29579) was chosen by the research collaboration ENIGMA to explore tools and protocols for bringing this anaerobe to model status. Here, we describe a collection of genetic constructs generated by ENIGMA that are available to the research community.

scholarly journals Building Tools to Facilitate Data Reuse

2017 ◽  
Vol 11 (2) ◽  
pp. 1-12
Author(s):  
Stefanie Kethers ◽  
Andrew Treloar ◽  
Mingfang Wu
Keyword(s):  
Lessons Learned ◽  
Data Reuse ◽  
Data Service ◽  
Research Institutions ◽  
Australian Government ◽  
National Data ◽  
Software Infrastructure

The Australian National Data Service (ANDS) has been funded by the Australian Government since 2009, with a goal to increase the value of data to researchers, research institutions and the nation. To achieve this goal, ANDS has funded more than 200 projects under seven programs. This paper provides an overview of one of these programs, the Applications Program, which focused on funding software infrastructure to enable data reuse to demonstrate the value of making data available to researchers. The paper also presents some representative projects, a summary of what the program has achieved, and lessons learned. 

scholarly journals Integrated Biodiversity Infrastructure for Decision Making 

2019 ◽  
Vol 3 ◽  
Author(s):  
Hamish Holewa
Keyword(s):  
Cultural Change ◽  
Decision Makers ◽  
Collaborative Partnership ◽  
Australian Government ◽  
Biodiversity Data ◽  
Virtual Laboratories ◽  
Data Stewardship ◽  
Industry Engagement ◽  
Analytical Services ◽  
Biodiversity Information

The Atlas of Living Australia (ALA) is an Australian Government supported collaborative partnership of organisations that have stewardship of Australian biodiversity data. The ALA (www.ala.org.au) provides research infrastructure that enables delivery of biodiversity information to over 45,000 unique users in research, industry and government per annum. It delivers impact and enables research excellence in fields such as biodiversity, environmental management, ecology and genetic sciences. Integrated and consistent infrastructure and processes are fundamental to increasing value of collections and associated data. The Atlas of Living Australia has a mature industry engagement program that provides data standardisation, quality and analytical services to decision makers in all tiers of Australian government (local, state and federal). This program is built on formal partnerships between data providers (collection institutions) and analytical services (such as Virtual Laboratories and Research and Science Clouds www.ecocloud.org.au). The provision of high quality, authoritative data is critical to utilisation and uptake of these services and sector sustainability. This presentation will showcase data service and analytical methods for decision makers within the Australian context. It will also explore how international efforts such as DiSSCo assist in data stewardship, cultural change and system enhancement.

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