scholarly journals Quick tips to perform a metabolomics study

2016 ◽  
Author(s):  
Biswapriya B Misra
Keyword(s):  
Metabolic Regulation ◽  
Strain Improvement ◽  
Basic Research ◽  
Industrial Applications ◽  
Early Career ◽  
Early Career Researchers ◽  
Research Areas ◽  
Metabolomics Study ◽  
And Behavior ◽  
Potential Use

Nascent, burgeoning, youngest, ‘connecting link between genotype and phenotype’ are just some of the phrases associated with this ‘omics’ where small molecules (metabolites with molecular weight < 2000 Daltons) are studied in biological systems, i.e., metabolomics. Currently, due to recent advances in the field, metabolomics has demanded large attention from scientists as it has shown tremendous potential in basic research such as the study interaction of ‘omes’ and the discovery of new biochemical pathways. Other areas of impact include metabolic regulation, disease biomarker identification, personalized medicine, clinical trials, toxicology, nutrigenomics, medicine diagnosis, and agriculture. Also included are industrial applications such as metabolic engineering in strain improvement in microbes. Here, the attempt is to get the scientific community interested and excited about the potential use of metabolomics in their existing research areas, by widening its dimensions to another level of data-oriented science leading to better interpretation and understanding of the function and behavior of organisms. Nonetheless, while excellent pioneering reviews and extremely successful studies exist in metabolomics, a summary and/or overview of this area is lacking at this moment. Thus, the target audience are not only researchers who are venturing into metabolomics, but also early career researchers, investigators, students, and individuals interested in implementing metabolomics in their current research and field. Typically, study design to publication can span from months to years in some cases, but without a general grasp of how beneficial and easy to implement metabolomics can be, further inquiry into the field may be mistakenly overlooked. I attempt to summarize and encapsulate the ‘usual’ trends in such efforts, identifying the critical steps to make the trends all fit into these quick tips. The objective of this article is to provide a bird’s eye view of metabolomics research that can be enjoyed over a mug of coffee while simultaneously providing an outline for a variety of audiences interested in incorporating this fascinating field in their work.

scholarly journals Quick tips to perform a metabolomics study

2016 ◽  
Author(s):  
Biswapriya B Misra
Keyword(s):  
Metabolic Regulation ◽  
Strain Improvement ◽  
Basic Research ◽  
Industrial Applications ◽  
Early Career ◽  
Early Career Researchers ◽  
Research Areas ◽  
Metabolomics Study ◽  
And Behavior ◽  
Potential Use

Nascent, burgeoning, youngest, ‘connecting link between genotype and phenotype’ are just some of the phrases associated with this ‘omics’ where small molecules (metabolites with molecular weight < 2000 Daltons) are studied in biological systems, i.e., metabolomics. Currently, due to recent advances in the field, metabolomics has demanded large attention from scientists as it has shown tremendous potential in basic research such as the study interaction of ‘omes’ and the discovery of new biochemical pathways. Other areas of impact include metabolic regulation, disease biomarker identification, personalized medicine, clinical trials, toxicology, nutrigenomics, medicine diagnosis, and agriculture. Also included are industrial applications such as metabolic engineering in strain improvement in microbes. Here, the attempt is to get the scientific community interested and excited about the potential use of metabolomics in their existing research areas, by widening its dimensions to another level of data-oriented science leading to better interpretation and understanding of the function and behavior of organisms. Nonetheless, while excellent pioneering reviews and extremely successful studies exist in metabolomics, a summary and/or overview of this area is lacking at this moment. Thus, the target audience are not only researchers who are venturing into metabolomics, but also early career researchers, investigators, students, and individuals interested in implementing metabolomics in their current research and field. Typically, study design to publication can span from months to years in some cases, but without a general grasp of how beneficial and easy to implement metabolomics can be, further inquiry into the field may be mistakenly overlooked. I attempt to summarize and encapsulate the ‘usual’ trends in such efforts, identifying the critical steps to make the trends all fit into these quick tips. The objective of this article is to provide a bird’s eye view of metabolomics research that can be enjoyed over a mug of coffee while simultaneously providing an outline for a variety of audiences interested in incorporating this fascinating field in their work.

Support early-career researchers for post-pandemic prospects

Nature ◽  
2020 ◽  
Vol 580 (7802) ◽  
pp. 185-185 ◽  
Author(s):  
Arild Husby ◽  
Gemma Modinos
Keyword(s):  
Early Career ◽  
Early Career Researchers

Future Physiology 2019: Uniting early career researchers

2019 ◽  
pp. 25-25
Author(s):  
Katie Hesketh ◽  
Mark Viggars
Keyword(s):  
Early Career ◽  
Early Career Researchers

Temporal Focus

2020 ◽  
Author(s):  
Abbie J. Shipp
Keyword(s):  
Well Being ◽  
Psychology Research ◽  
The Past ◽  
Research Areas ◽  
The Future ◽  
Behavior Based ◽  
The Individual ◽  
And Behavior ◽  
Temporal Focus

Temporal focus is the individual tendency to characteristically think more or less about the past, present, and future. Although originally rooted in early work from psychology, research on temporal focus has been steadily growing in a number of research areas, particularly since Zimbardo and Boyd’s (1999) influential article on the topic. This chapter will review temporal focus research from the past to the present, including how temporal focus has been conceptualized and measured, and which correlates and outcomes have been tested in terms of well-being and behavior. Based on this review, an agenda for research is created to direct temporal focus research in the future.

scholarly journals Positioning for success: building capacity in academic competencies for early-career researchers in sub-Saharan Africa

2019 ◽  
Vol 6 ◽  
Author(s):  
C. Merritt ◽  
H. Jack ◽  
W. Mangezi ◽  
D. Chibanda ◽  
M. Abas
Keyword(s):  
Mental Health ◽  
Capacity Building ◽  
Low Cost ◽  
Early Career ◽  
Sub Saharan Africa ◽  
Training Experience ◽  
African Countries ◽  
Early Career Researchers ◽  
Academic Competencies ◽  
Sub Saharan

Background. Capacity building is essential in low- and middle-income countries (LMICs) to address the gap in skills to conduct and implement research. Capacity building must not only include scientific and technical knowledge, but also broader competencies, such as writing, disseminating research and achieving work–life balance. These skills are thought to promote long-term career success for researchers in high-income countries (HICs) but the availability of such training is limited in LMICs. Methods. This paper presents the contextualisation and implementation of the Academic Competencies Series (ACES). ACES is an early-career researcher development programme adapted from a UK university. Through consultation between HIC and LMIC partners, an innovative series of 10 workshops was designed covering themes of self-development, engagement and writing skills. ACES formed part of the African Mental Health Research Initiative (AMARI), a multi-national LMIC-led consortium to recruit, train, support and network early-career mental health researchers from four sub-Saharan African countries. Results. Of the 10 ACES modules, three were HIC-LMIC co-led, four led by HIC facilitators with LMIC training experience and three led by external consultants from HICs. Six workshops were delivered face to face and four by webinar. Course attendance was over 90% and the delivery cost was approximately US$4500 per researcher trained. Challenges of adaptation, attendance and technical issues are described for the first round of workshops. Conclusions. This paper indicates that a skills development series for early-career researchers can be contextualised and implemented in LMIC settings, and is feasible for co-delivery with local partners at relatively low cost.

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