scholarly journals A Gauge model-based analysis of: Reduction(s) in osmolyte infusion interval and its effects on the aggregate measure of systemic failure for a unicellular system

2015 ◽  
Author(s):  
Imadol V Jeff-Eke
Keyword(s):  
Biological Systems ◽  
Theoretical Problem ◽  
Gauge Model ◽  
Intracellular Space ◽  
Limited Availability ◽  
Model Based ◽  
Model Based Analysis ◽  
Aggregate Measure

This is a companion to A Gauge model for analysis of Biological systems. Here we reconcile the gauge model with a “real” system, which in this case is a unicellular system. We address effects of infusion of free osmolytes into an intracellular space of interest, and how changes to the frequency of infusion affects the aggregate measure of systemic failure. We also describe limitations to the functionality of the system that may stem from a limited availability of resources. We end by introducing a theoretical problem related to how well the system can tolerate random and extreme changes to the frequency of osmolytes presented via infusion.

scholarly journals A Gauge model-based analysis of: Reduction(s) in osmolyte infusion interval and its effects on the aggregate measure of systemic failure for a unicellular system

2015 ◽  
Author(s):  
Imadol V Jeff-Eke
Keyword(s):  
Biological Systems ◽  
Theoretical Problem ◽  
Gauge Model ◽  
Intracellular Space ◽  
Limited Availability ◽  
Model Based ◽  
Model Based Analysis ◽  
Aggregate Measure

This is a companion to A Gauge model for analysis of Biological systems. Here we reconcile the gauge model with a “real” system, which in this case is a unicellular system. We address effects of infusion of free osmolytes into an intracellular space of interest, and how changes to the frequency of infusion affects the aggregate measure of systemic failure. We also describe limitations to the functionality of the system that may stem from a limited availability of resources. We end by introducing a theoretical problem related to how well the system can tolerate random and extreme changes to the frequency of osmolytes presented via infusion.

scholarly journals Reduction(s) in osmolyte infusion interval and its effect on the aggregate measure of systemic failure: for a unicellular system

2015 ◽  
Author(s):  
Imadol V Jeff-Eke
Keyword(s):  
Biological Systems ◽  
Theoretical Problem ◽  
Gauge Model ◽  
Limited Availability ◽  
Aggregate Measure

This is a companion to A Gauge model for analysis of Biological systems. Here we reconcile the gauge model with a “real” system, which in this case is a unicellular system. We address effects of changes to the frequency of osmolyte infusion, on the aggregate measure of systemic failure. We also describe limitations to the functionality of the system that may stem from limited availability of resources. We end by introducing a theoretical problem related to how well the system can tolerate random changes to the frequency of osmolytes infusion.

scholarly journals A proposed solution to the problem posed by reduction(s) in osmolyte infusion interval: A theory on the origins of stimulus-functional response pairs in biological systems

2015 ◽  
Author(s):  
Imadol V Jeff-Eke
Keyword(s):  
Functional Response ◽  
Biological Systems ◽  
Cellular System ◽  
Intracellular Space ◽  
Stimulus Response ◽  
Aggregate Measure

This work follows as a response to a problem posed in a previous work: Effects of Osmolyte Infusion Interval Reductions on the Aggregate Measure of Systemic Failure: for a unicellular system. Here we propose and explore a probable solution to the posed problem of how well a cellular system can tolerate random changes to the frequency of osmolytes infused into an intracellular space of interest. The proposed solution involves the ability of biological systems to anticipate occurrences of imminent challenge stimuli, and by so doing, initiate the required functional response(s) against their [stimuli] effects. By stating anticipatory roles in biological systems, we are suggesting a possible origin for the stimulus-response pairing noted in these systems.

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