scholarly journals Papular mucinosis (papular lichen myxedematosus): Clinical and histopathological evaluation

2021 ◽  
Vol 12 (2) ◽  
pp. 113-119
Author(s):  
Khalifa Sharquie ◽  
Raed I Jabbar

Background: Papular mucinosis is a variety of mucinosis characterized by excessive production of mucin by fibroblasts and deposition in the dermis. It manifests itself with fleshy papules or plaques in different sites of the body and taking different clinical morphological cutaneous features. Objective: The objective is to report and evaluate the different clinical and histopathological features of the disease in Iraqi patients. Patients and Methods: This is a case series and a clinical descriptive study in which ten patients with papular mucinosis were reported during the period from 2012 through 2019. The age ranged from 4 to 56 years, with seven females and three males. Clinical evaluation regarding histories of the disease and examination was carried out. General investigation was done and skin biopsy for histopathological assessment was conducted. Results: Nine patients were adults, with their age ranging from 20 to 56 years, a mean of around 35 years, and only one 4-year-old child. It is a disease with a female predominance, as observed in 7 (70%) females. The common sites of involvement were the face but the rash may extend to affect the neck and upper arms. The rash appeared in the form of skin-colored or red fleshy papules and plaques or in diffuse erythematous orange peel-like forms. The rash was asymptomatic in most patients. The pathology of the disease clarified the diffuse deposition of mucin in the dermis, as was demonstrated with H&E staining. Conclusion: Papular mucinosis is a rare disease characterized by mucin deposition in the skin affecting mostly adult females. The face is commonly involved together with other areas such as the neck and upper arms, but the trunk and lower limbs are spared. It manifests itself with different clinical morphological cutaneous features. Papular granuloma annulare must be considered as an important differential diagnosis in all cases of papular mucinosis.

PEDIATRICS ◽  
1970 ◽  
Vol 45 (4) ◽  
pp. 588-588
Author(s):  
T. E. C.

Both Rosén von Rosenstein (1706-1773)1 and François Boissier de Sauvages (1706-1767)2 came close to differentiating varicella from variola. But, it was left to William Heberden3 to give the first detailed description of chickenpox as a disease sui generis in 1767 as follows: These pocks break out on many without any illness or previous sign: in others they are preceded by a little degree of chillness, lassitude, cough, broken sleep, wandering pains, loss of appetite and feverishness for three days. In some patients I have observed them to make their first appearance on the back, but this perhaps is not constant. Most of them are of the common size of the smallpox but some are less. I never saw them confluent nor very numerous. The greatest number which I ever observed was about twelve in the face, and two hundred over the rest of the body. On the first day of the eruption they are reddish: on the second day there is at the top of most of them a very small bladder about the size of a millet seed. This is sometimes full of a watery and colourless, sometimes of a yellowish, liquor contained between the cuticle and the skin. On the second or at the farthest on the third day from the beginning of the eruption as many of the pocks as are not broken seem arrived at their full maturity, and those which are fullest of that yellow liquor very much resemble what the genuine smallpox are on the fifth or sixth day especially where there happens to be a larger space than ordinary occupied by the extravasated serum.


2020 ◽  
Vol 3 (2) ◽  
pp. 45-54
Author(s):  
John Ogunkoya ◽  
Afolashade Oluwole ◽  
Ezuduemoih Daniel ◽  
Osaze Ehioghae ◽  
Oyebimpe Ajiboye

Background: Pulmonary thromboembolism is total or partial obstruction of one or more divisions of pulmonary arterial vasculature. It is a common disease presentation that is well studied and documented in the United States of America and Western Europe. It is often the result of part of a thrombotic lesion in deep veins (Deep Vein Thrombosis) elsewhere in the body most commonly the lower limbs and the pelvic region. There are few documented cases in Nigeria and sub-Saharan Africa as a result of poorly equipped hospitals and poorly trained health care personnel. Case presentation: Twenty-Nine (29) cases were seen in a Private Tertiary institution in Ogun State, Nigeria. Computerized Tomography with Pulmonary Angiography had helped to confirm these cases, with prompt intervention thereby reducing morbidity and mortality significantly. Only 3(three) mortality was recorded out of 29 cases seen between July 2016 and June 2020. Discussion and conclusion: Pulmonary thromboembolism is not uncommon in Nigerians and black Africans as available data previously suggested. All hands must be on deck to identify potential cases and investigate at-risk individuals who have clinical symptoms that are often misdiagnosed as other disease entities.


1800 ◽  
Vol 90 ◽  
pp. 98-105 ◽  

Dear Sir, The Maucauco you have been so obliging as to give me for the purpose of dissection, has proved a subject of considerable interest. This animal, the Lemur tardigradus of Linnæus, was injected, with a view to exhibit the course of the arteries; and they present a very unusual deviation from the ordinary arrange­ment of this class of blood-vessels in animals generally. Before I had leisure to inquire further into this peculiarity, I presented a drawing of the appearances to my friend Dr. Shaw, of the British Museum, for the purpose of being made public in his work of natural history, now in the press. Since that time, I have, through Dr. Shaw’s assistance, been enabled to investi­gate this subject somewhat farther; and, if you consider the following account in any degree worthy the attention of the Royal Society, I shall receive an additional honour by its pro­ceeding through your hands. The Lemur tardigradus , in its injected state, accompanies this paper; and, for the kind of preparation, the vessels are filled with more than ordinary success. The arteries alone are injected; and the peculiarity of their arrangement is to be observed in the axillary arteries, and in the iliacs. These vessels, at their entrance into the upper and lower limbs, are suddenly divided into a number of equal-sized cylinders, which occasionally anastomose with each other. They are exclusively distributed on the muscles; whilst the arteries sent to all the parts of the body, excepting the limbs, divide in the usual arborescent form; and, even those arteries of the limbs which are employed upon substances not muscular, branch off like the common blood-­vessels. I counted twenty-three of these cylinders, parallel to each other, about the middle of the upper arm; and seventeen in the inguinal fasciculus.


2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Zara Sheikh ◽  
Sadasivam Selvakumar ◽  
Patrick Goon

Abstract Aneurysmal disease can occur in any vessel in the body and occur most commonly the aorta, cerebral and popliteal arteries; however, aneurysms of the digital artery remain a rare presentation. They form an important differential diagnosis in any patient presenting with a mass in the hand. This report presents the case of a 64-year-old man with a true aneurysm of the common palmar digital artery who underwent successful repair, following excision and end to end anastomosis. Only 21 cases of true digital artery aneurysm have been reported; we review the literature pertaining to the diagnosis and management of digital artery aneurysms since they were first described by Baruch et al in 1977.


2020 ◽  
Vol 7 (3) ◽  
pp. 1-6
Author(s):  
Teodor Angelov ◽  
Valeri Malev ◽  
Georgi Tchernev

Epidermal cysts are the most common scalp cysts in clinical practice. They are most commonly located in the region of the face, neck, and trunk, and have been reported in many other topographic areas of the body. Clinically, they are present as free-moving nodules located below the skin, ranging in size from a few millimeters to a few centimeters in diameter. Histopathologically, they are defined as benign tumor formations with a very low risk of malignancy. The differential diagnosis includes: lipoma, neurofibroma, salivary gland adenoma, vascular lesion and fibroid, and Trichilemmal cyst. The most common treatment for epidermal cysts is surgical excision with removal of all contents without compromising the integrity of the capsule. In this publication, we present five clinical cases of patients with epidermal cysts in different topographic regions of the body. The patients were treated surgically by elliptical excision and complete removal of epidermal cysts without rupture. The defects were closed with single discontinued skin sutures and the sutures were removed on an 8- / 14-postoperative day. No recurrence was observed in the postoperative period.


2013 ◽  
Vol 19 (3) ◽  
pp. 124-129
Author(s):  
P. Gavrilidou ◽  
D.M. Iliescu ◽  
Baz R. ◽  
L.M. Rusali ◽  
P. Bordei

Abstract the methods of dissection and analysis of angioCT’s. Each of the details was analyzed comparatively on both sides of the body assessing: the origin of the superior thyroid artery in relation to the carotid bifurcation, the face of the external carotid artery that gives origin and the traject of the artery from the origin to the glandular parenchyma. The origin of the superior thyroid artery was evaluated on a number of 64 cases, most frequently having its origin from the external carotid artery, an aspect met 53.125 % of cases, at a distance that was between 1-18 mm. In 28.125 % of cases the superior thyroid artery had its origin in the common carotid trunk at a distance of 1-10 mm caudal to the terminal bifurcation of the common carotid. In 18.75 % of cases, the thyroid artery originated from the carotid bifurcation, which thus ends up by trifurcation. The side of the vessel that emerges the superior thyroid artery was assessed on 42 cases; most commonly the superior thyroid artery having its origin on the medial face, an aspect found in 66.67 % of cases; in 23.81 % of cases originated from the posterior medial and only two cases (4.76 % of cases), both on the left side(8.70 % of cases on the left), the origin of the superior thyroid artery was located on the anterior, respectively faces of the common carotid artery. The traject of the superior thyroid artery was followed on 53 cases, in most cases the artery showing initially a horizontal traject (transverse) towards medially for 1-4 cm, then became obliquely downward, an aspect met in 28.30 % of cases and in 22.64 % of cases, the artery was obliquely downward from its origin. In 11.32 % of cases the traject was obliquely ascending and in 9.43 % of cases the artery was initially obliquely upward for 2-3 cm, after which became transverse. For the remaining 28.30 % of the cases we have met a number of other 5 different patterns of traject but in a small percentage for each of them (5.66% of cases).


2021 ◽  
Vol 24 (2) ◽  
pp. 145-150
Author(s):  
Vladislav N. Grebenyuk ◽  
Igor V. Popov ◽  
Vera L. Isaeva ◽  
Natalya F. Zatorskaya

Microbial eczema among the various clinical forms of eczema in the structure of incidence ranks is on the second position after the true one. Adults get sick more often than children. The pathogenesis of microbial eczema is based on misfunctions in the immune status and microbial sensitization of the body Due to bacterial background, as well as dysbiosis in the microbiome. The clinical picture of the disease is characterized by asymmetric localization of rashes on the limbs in the form of single plaques. The affected skin is reddish, squamous, slightly infiltrated. Outside the main foci, papulovesicular and pustular lesions, crusts are observed. Rash is not not always accompanied by itching. Microbial eczema was of a limited nature, manifested by coin-shaped foci, dot weeping, crusts. We observed a patient of 15 years before admission to the hospital was ill for 8 months. At the same time, during the last three months, the pathological process on her skin existed acutely without any dynamics. The occurrence of a rash is not associated with anything. Multiple efflorescence were located throughout the skin, on the scalp, ears, in the ear region, on the face, neck, torso, upper and lower limbs, buttocks, accompanied by severe itching. The inflammatory pathological process was represented by excoriations, wet spots, erosions, crusts and erythematous-squamous foci of various shapes and sizes. Dermographism pink. Repeated outpatient treatment brought temporary improvement. Due to the lack of therapeutic effect in the last 3 months, the patient was hospitalized in the branch Kolomensky. A comprehensive clinical and laboratory examination diagnosed disseminated subacute microbial eczema. Against the background of adequate therapy, the anti-inflammatory pathological process was completely resolved. Recommendations are given to maintain the achieved therapeutic effect.


2020 ◽  
Vol 9 (2) ◽  
pp. 1-5
Author(s):  
Ravi Singh Dogra ◽  
Arjun Singh ◽  
Vinay Bhardwaj ◽  
Poonam ◽  
Srijan Pandey ◽  
...  

Tuberculosis is a highly prevalent disease in developing countries, the majority of cases are pulmonary and rest are extra-pulmonary. Cervical LN tuberculosis is one of the most common types of extra-pulmonary tuberculosis. Isolated cervical tubercular Lymphadenitis without accompanying pulmonary tuberculosis or another form of tuberculosis in the body is rare and, when present, requires thorough clinical examination and investigation. In the investigation of such patients, FNAC plays a major role, and aspirate should be tested for AFB through ZN stain and CBNAAT (PCR). Cervical tubercular Lymphadenitis is mainly a disease of young with a female predominance. All patients of cervical tubercular Lymphadenitis must receive antitubercular therapy with strict follow up for compliance and possible side effects from treatment.


2021 ◽  
Vol 14 (1) ◽  
pp. 7-12
Author(s):  
Iffat Islam Khan ◽  
Md. Mahbubul Islam ◽  
Redoy Ranjan ◽  
Mohammad Tariqul Islam ◽  
Asit Baran Adhikary

This article has no abstract. The first 100 words appear below: A 60-year-old male presented with weakness of the left side of the body followed by a sudden fall on the ground while working in the field, with difficulty in speech for 03 months. Weakness was sudden in onset which involved left upper and lower limbs with the inability to move the left side of the body and difficulty in walking. The patient also noticed that there was a deviation of the face towards the right side associated with dribbling of food with difficulty in speech but can follow the command with difficulty. There was also urinary incontinence for the same duration, but the bowel movement was normal.


2020 ◽  
Vol 5 (3 And 4) ◽  
pp. 155-160
Author(s):  
Mohsen Aghapoor ◽  
◽  
Babak Alijani Alijani ◽  
Mahsa Pakseresht-Mogharab ◽  
◽  
...  

Background and Importance: Spondylodiscitis is an inflammatory disease of the body of one or more vertebrae and intervertebral disc. The fungal etiology of this disease is rare, particularly in patients without immunodeficiency. Delay in diagnosis and treatment of this disease can lead to complications and even death. Case Presentation: A 63-year-old diabetic female patient, who had a history of spinal surgery and complaining radicular lumbar pain in both lower limbs with a probable diagnosis of spondylodiscitis, underwent partial L2 and complete L3 and L4 corpectomy and fusion. As a result of pathology from tissue biopsy specimen, Aspergillus fungi were observed. There was no evidence of immunodeficiency in the patient. The patient was treated with Itraconazole 100 mg twice a day for two months. Pain, neurological symptom, and laboratory tests improved. Conclusion: The debridement surgery coupled with antifungal drugs can lead to the best therapeutic results.


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