Evaluation of the efficacy of a combination – measles, mumps and rubella vaccine in the treatment of plantar warts

Nagat Sobhy Mohamad; Fayrouz Badran; Esraa Yakout

doi:10.7241/ourd.20134.118

Evaluation of the efficacy of a combination – measles, mumps and rubella vaccine in the treatment of plantar warts

Our Dermatology Online ◽

10.7241/ourd.20134.118 ◽

2013 ◽

Vol 4 (4) ◽

pp. 463-467 ◽

Cited By ~ 2

Author(s):

Nagat Sobhy Mohamad ◽

Fayrouz Badran ◽

Esraa Yakout

Keyword(s):

Rubella Vaccine ◽

Plantar Warts

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Intralesional injection of Candida albicans antigen versus measles, mumps, and rubella vaccine for treatment of plantar warts

Acta Dermatovenerologica Alpina Pannonica et Adriatica ◽

10.15570/actaapa.2021.1 ◽

2021 ◽

Vol 30 (1) ◽

Author(s):

Rania Mahmoud Rageh ◽

El-Sayed Shaaban Hewedy ◽

Doaa Salah Hegab

Keyword(s):

Candida Albicans ◽

Intralesional Injection ◽

Rubella Vaccine ◽

Plantar Warts

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Intralesional Vitamin D Injection May Be an Effective Treatment Option for Warts

Journal of Cutaneous Medicine and Surgery ◽

10.1177/1203475415602841 ◽

2015 ◽

Vol 20 (2) ◽

pp. 118-122 ◽

Cited By ~ 20

Author(s):

Habibullah Aktaş ◽

Can Ergin ◽

Betül Demir ◽

Özlem Ekiz

Keyword(s):

Vitamin D ◽

Candida Albicans ◽

Adverse Effects ◽

Effective Treatment ◽

Treatment Option ◽

Complete Resolution ◽

Efficacy And Safety ◽

Effective Treatment Option ◽

Rubella Vaccine ◽

Plantar Warts

Background: Plantar warts are typically resistant to treatment. In recent years, treatments have included administration of intralesional tuberculin; measles, mumps, rubella vaccine; and Candida albicans antigen immunotherapy. To the best of our knowledge, there are no reports of intralesional vitamin D administration for the treatment of warts. Aim: To evaluate the efficacy and safety of intralesional vitamin D treatment for plantar warts. Methods: Twenty patients with single or multiple plantar warts were included in this study. Vitamin D3 (0.2 mL, 7.5 mg/mL) was injected into the base of the warts after prilocaine (0.1 mL, 20 mg/mL) injection. A maximum of 5 warts were treated in 1 session, with at maximum 2 injections performed at 4-week intervals. Results: In total, 16 of 20 patients (80%) showed complete resolution of warts, and 1 patient showed partial resolution. Three patients failed to show any response. No recurrence or serious adverse effects were observed. Conclusion: Intralesional vitamin D3 may be an effective treatment option for warts.

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Intralesional Measles, Mumps, and Rubella Vaccine Versus Intralesional Candida Antigen in the Treatment of Common and Plantar Warts

Journal of Cutaneous Medicine and Surgery ◽

10.1177/1203475421991130 ◽

2021 ◽

pp. 120347542199113

Author(s):

Ahmad Nofal ◽

Reda Ezz El-arab ◽

Mohamed Nasr ◽

Rania Alakad

Keyword(s):

Therapeutic Response ◽

Comparable Efficacy ◽

Efficacy And Safety ◽

Mmr Vaccine ◽

Rubella Vaccine ◽

Complete Clearance ◽

Common Warts ◽

The Difference ◽

Plantar Warts

Background Intralesional immunotherapy has been effectively used in the treatment of warts; however, comparative studies between different antigens are limited. Objective To evaluate the efficacy and safety of intralesional measles, mumps, and rubella (MMR) vaccine compared with intralesional Candida antigen for the treatment of multiple common and plantar warts. Methods Sixty-eight adult patients with multiple common and plantar warts were randomly assigned into two groups, each containing 34 patients. The first group received intralesional MMR vaccine, while the second group received intralesional Candida antigen. Each treatment was injected into the largest wart at 2-week intervals until complete clearance or for a maximum of 5 sessions. Results The overall therapeutic response was higher in the Candida antigen group (73.5%) compared with the MMR group (67.7%); however, the difference was not statistically significant. Complete clearance of common warts was higher in the Candida antigen group, while that of plantar warts was higher in the MMR group. Adverse effects were transient and well tolerated in both groups. No recurrence was detected during the 6-month follow-up period. Conclusion Intralesional MMR and intralesional Candida antigen showed comparable efficacy and safety in the treatment of common and plantar warts.

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