scholarly journals Adverse Childhood Experiences and Substance Use: The Mediating Role of Perceptions of Harm and Peer and Parental Attitudes

2021 ◽  
Vol 8 (1) ◽  
pp. 1-14
Author(s):  
Jérémie Richard ◽  
Loredana Marchica ◽  
Anthony Sciola ◽  
William Ivoska ◽  
Jeffrey Derevensky
Keyword(s):  
Substance Use ◽  
Binge Drinking ◽  
Adverse Childhood Experiences ◽  
Parental Attitudes ◽  
Age And Gender ◽  
Childhood Experiences ◽  
Peer Attitudes ◽  
Adverse Childhood ◽  
And Gender ◽  
The Relationship

Objectives: Adverse childhood experiences (ACEs) are related to the development of a range of mental health problems and risky behaviors. Generally, adolescents who experienced a greater number of ACEs have been found to be at increased risk of substance use behaviors. This study investigated the association between ACEs and substance use (i.e., cigarette smoking, binge drinking, and cannabis use) as mediated by perceptions of harm and perceived peer and parental attitudes towards each substance. Methods: A survey was completed by 6,304 students aged 12 to 18 (M = 14.75, SD = 1.76) in Wood County, Ohio, assessing ACEs, substance use behaviors, perceptions of harm and perceived peer and parental attitudes towards each substance. Mediation models controlling for age and gender were conducted for each substance use behavior including perceptions of harm and perceived peer and parental attitudes specific to each substance. Results: Controlling for age and gender, perceptions of harm and peer attitudes towards binge drinking partially mediated the relationship between ACEs and past month binge-drinking. For past month cannabis and cigarette smoking, peer and parental attitudes, but not perceptions of harm, partially mediated the relationship between ACEs and past month engagement in these substances. Implications: Greater perceptions of harm and negative attitudes by parents or peers may be protective against substance use behaviors among youth that have experienced ACEs. Early interventions focusing on increasing perceptions of harm along with promoting negative parental and peer attitudes towards substance use could decrease rates of use among those who experienced ACEs.

scholarly journals Identifying Targets for Substance Use Prevention in Young People Exposed to Childhood Adversity: Protocol for a Systematic Review (Preprint)

2020 ◽  
Author(s):  
Lucinda Rachel Grummitt ◽  
Erin Veronica Kelly ◽  
Emma Louise Barrett ◽  
Katherine M Keyes ◽  
Nicola Clare Newton
Keyword(s):  
Substance Use ◽  
Young People ◽  
Adverse Childhood Experiences ◽  
Meta Analysis ◽  
Childhood Adversity ◽  
Substance Use Prevention ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Quantitative Synthesis ◽  
The Relationship

BACKGROUND Adverse childhood experiences are prevalent robust risk factors for the development of substance use problems. However, less is known about the causal mechanisms that explain these relationships. While directly preventing adverse childhood experiences is ideal, it is not always possible. In such cases, the mechanisms themselves may be amenable to intervention, allowing for the effective prevention of problematic substance use among children exposed to adversity. Identifying such mechanisms is therefore a critical step for efforts aiming to reduce the high individual and societal burdens associated with substance use globally. OBJECTIVE This study aims to systematically identify and synthesize evidence on the modifiable mediators and moderators of the relationship between adverse childhood experiences and substance use outcomes in young people (age 10-24 years). METHODS A systematic review will be conducted using PubMed, MEDLINE, PsycINFO, Web of Science, and CINAHL databases to determine the modifiable mediators and moderators of the relationship between adverse childhood experiences and substance use in young people. Data from the review will be qualitatively synthesized, unless we identify a sufficient number of studies (at least five) that examine the same type of adversity (eg, physical or sexual abuse) and the same mediator/moderator, in which case a quantitative synthesis (meta-analysis) will be conducted. If a quantitative synthesis is warranted, standardized effect estimates of the indirect (mediated) effect between adverse childhood experiences and substance use outcomes will be combined using a random-effects meta-analysis. Mediators/moderators will be grouped according to a socioecological perspective, using the four levels of individual, interpersonal, community, and public policy/culture. RESULTS Electronic searches were completed in August 2019. A total of 4004 studies were included for screening after removing duplicates. After evaluating titles and abstracts against eligibility criteria, a further 3590 studies were excluded, leaving 415 studies for full-text screening. The results of the review are expected to be available by December 2020. CONCLUSIONS The mechanisms linking adverse childhood experiences and substance use outcomes in young people are vital targets for substance use prevention efforts. This review will provide evidence to inform the development of prevention strategies in order to interrupt the negative life trajectory that can begin with childhood adversity. CLINICALTRIAL PROSPERO International Prospective Register of Systematic Reviews CRD42020148773; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020148773 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/22368

scholarly journals Identifying Targets for Substance Use Prevention in Young People Exposed to Childhood Adversity: Protocol for a Systematic Review

10.2196/22368 ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. e22368
Author(s):  
Lucinda Rachel Grummitt ◽  
Erin Veronica Kelly ◽  
Emma Louise Barrett ◽  
Katherine M Keyes ◽  
Nicola Clare Newton
Keyword(s):  
Substance Use ◽  
Young People ◽  
Adverse Childhood Experiences ◽  
Meta Analysis ◽  
Childhood Adversity ◽  
Substance Use Prevention ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Quantitative Synthesis ◽  
The Relationship

Background Adverse childhood experiences are prevalent robust risk factors for the development of substance use problems. However, less is known about the causal mechanisms that explain these relationships. While directly preventing adverse childhood experiences is ideal, it is not always possible. In such cases, the mechanisms themselves may be amenable to intervention, allowing for the effective prevention of problematic substance use among children exposed to adversity. Identifying such mechanisms is therefore a critical step for efforts aiming to reduce the high individual and societal burdens associated with substance use globally. Objective This study aims to systematically identify and synthesize evidence on the modifiable mediators and moderators of the relationship between adverse childhood experiences and substance use outcomes in young people (age 10-24 years). Methods A systematic review will be conducted using PubMed, MEDLINE, PsycINFO, Web of Science, and CINAHL databases to determine the modifiable mediators and moderators of the relationship between adverse childhood experiences and substance use in young people. Data from the review will be qualitatively synthesized, unless we identify a sufficient number of studies (at least five) that examine the same type of adversity (eg, physical or sexual abuse) and the same mediator/moderator, in which case a quantitative synthesis (meta-analysis) will be conducted. If a quantitative synthesis is warranted, standardized effect estimates of the indirect (mediated) effect between adverse childhood experiences and substance use outcomes will be combined using a random-effects meta-analysis. Mediators/moderators will be grouped according to a socioecological perspective, using the four levels of individual, interpersonal, community, and public policy/culture. Results Electronic searches were completed in August 2019. A total of 4004 studies were included for screening after removing duplicates. After evaluating titles and abstracts against eligibility criteria, a further 3590 studies were excluded, leaving 415 studies for full-text screening. The results of the review are expected to be available by December 2020. Conclusions The mechanisms linking adverse childhood experiences and substance use outcomes in young people are vital targets for substance use prevention efforts. This review will provide evidence to inform the development of prevention strategies in order to interrupt the negative life trajectory that can begin with childhood adversity. Trial Registration PROSPERO International Prospective Register of Systematic Reviews CRD42020148773; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020148773 International Registered Report Identifier (IRRID) DERR1-10.2196/22368

scholarly journals Adverse Childhood Experiences are Associated with High-Intensity Binge Drinking Behavior in Adulthood and Mediated by Psychiatric Disorders

2020 ◽  
Vol 55 (2) ◽  
pp. 204-214 ◽  
Author(s):  
Jeesun Jung ◽  
Daniel B Rosoff ◽  
Christine Muench ◽  
Audrey Luo ◽  
Martha Longley ◽  
...  
Keyword(s):  
Binge Drinking ◽  
Psychiatric Disorders ◽  
High Intensity ◽  
Adverse Childhood Experiences ◽  
Clinical Sample ◽  
Drinking Behavior ◽  
Stress Disorders ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
The Relationship

Abstract Aim High-intensity binge drinking (HIBD), defined as two or more times the gender-specific binge threshold, is rapidly increasing in the USA; however, the underlying contributing factors are poorly understood. This study investigated the relationship of adverse childhood experiences (ACEs) and HIBD. Methods Two independent, cross-sectional samples were analysed: (a) past 12-month drinkers in the National Epidemiological Survey on Alcohol and Related Conditions-III (NESARC-III; n = 25,552) and (b) the National Institute on Alcohol Abuse and Alcoholism (NIAAA) clinical sample (n = 1303). Multinomial logistic regressions were utilized to estimate adjusted odds ratios (AORs) of ACEs on HIBD. Mediation analysis was performed to examine the relationship between the past 12-month psychiatric disorders, ACEs, and HIBD. Results In the NESARC-III sample, prevalence of ACEs increased across all binge levels with the highest prevalence in extreme HIBD; ACEs were associated with higher odds for HIBD (level II, odds ratio (OR) = 1.2–1.4; P = 0.03–0.001; level III, OR = 1.3–1.9; P < 0.001). Prevalence of DSM-5 diagnoses also increased across all binge levels. Substance use disorders (SUD), mood, personality and post-traumatic stress disorders (PTSD) conferred the highest odds with extreme HIBD (SUD: OR = 21.32; mood: 1.73; personality: 2.84; PTSD: 1.97; all Ps < 0.001). Mediation analyses showed that the association between ACEs and HIBD was fully mediated through SUD (proportion mediated: 70–90%) and partially through other psychiatric disorders (20–80%). In the NIAAA sample, ACEs were 2–5 times more prevalent in extreme HIBD with higher odds (ORs = 3–8, P < 0.001) compared with non-bingers. Conclusion ACEs were associated with significantly increased odds of HIBD and the relationship may be mediated by psychiatric disorders.

scholarly journals Relationship between Adverse Childhood Experiences and substance use in youth offenders in Singapore

2021 ◽  
Vol 117 ◽  
pp. 105072
Author(s):  
Adam Oei ◽  
Chi Meng Chu ◽  
Dongdong Li ◽  
Nyx Ng ◽  
Carl Yeo ◽  
...  
Keyword(s):  
Substance Use ◽  
Adverse Childhood Experiences ◽  
Youth Offenders ◽  
Childhood Experiences ◽  
Adverse Childhood

scholarly journals The Relationship between Adverse Childhood Experiences and Sleep Problems among Adolescent Students: Mediation by Depression or Anxiety

2020 ◽  
Vol 18 (1) ◽  
pp. 236
Author(s):  
E-Jin Park ◽  
Shin-Young Kim ◽  
Yeeun Kim ◽  
Dajung Sung ◽  
Bora Kim ◽  
...  
Keyword(s):  
Adverse Childhood Experiences ◽  
Sleep Problems ◽  
Short Form ◽  
Community Sample ◽  
Mediating Effect ◽  
Self Report ◽  
Depression And Anxiety ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
The Relationship

Adverse childhood experiences (ACEs) are known to be closely related to depression, anxiety and sleep problems. However, it remains unclear whether adolescents with ACEs have sleep problems regardless of depression or anxiety or under a mediating effect from depression or anxiety. Therefore, our aim was to examine whether depression or anxiety mediates the relationship between ACEs and sleep problems in adolescents by using a community sample. The Early Trauma Inventory Self Report–Short Form (ETISR-SF) and List of Threatening Experiences Questionnaire (LTE-Q) were used to assess traumatic ACEs. Ultimately, data from 737 students (M = 448, F = 289, 15.1 ± 1.4 years old) were included in the statistical analysis. A total of 576 (78.1%) participants reported that they had experienced one or more ACEs. Adolescents with ACEs had higher levels of depression, anxiety and sleep problems than did adolescents without ACEs, and boys tended to experience more trauma than girls. Depression and anxiety partially mediated the relationship between ACEs and sleep problems. The results of this study suggest the need for depression and anxiety interventions for adolescents with ACEs to reduce the long-term consequences, including sleep problems and physical health problems.

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