scholarly journals The relationship between trough concentration of vancomycin and effect on methicillin-resistant Staphylococcus aureus in critically ill patients

2012 ◽  
Vol 102 (7) ◽  
pp. 616 ◽  
Author(s):  
J Y Cheong ◽  
M Makmor-Bakry ◽  
C L Lau ◽  
R Abdul Rahman
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Nicholas Raush ◽  
Kevin D Betthauser ◽  
Karen Shen ◽  
Tamara Krekel ◽  
Marin H Kollef

Abstract We carried out a prospective de-escalation study based on methicillin-resistant Staphylococcus aureus (MRSA) nasal cultures in intensive care unit patients with suspected pneumonia. Days of anti-MRSA therapy was significantly reduced in the intervention group (2 [0–3] days vs 1 [0–2] day; P < .01). Time to MRSA de-escalation was also shortened in the intervention group.


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